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July 5th, 2013

A self-assembled periodic table

Abstract:
Efforts to rationalise other aspects of chemistry into periodic table analogues therefore come with a degree of baggage. So to a paper subtitled ‘Forging a new "table of elements"' by Chad Mirkin and his coworkers at Northwestern University in Evanston, Illinois, US.1

Mirkin has pioneered the use of DNA to guide nanoparticles into self-assembled clusters and arrays. In 1996 he showed that the base sequence of single-stranded DNA attached to gold nanoparticles can encode an assembly instruction for joining nanoparticles in specified ways via pairing with other nanoparticles bearing complementary strands, creating a versatile and selective glue for nanotechnology.2 Since then, Mirkin and colleagues have made imaginative use of DNA-guided nano-assembly for biomedical technologies, such as a simple colourimetric sequence-recognition technique where the clustering of nanoparticles brings about changes in light scattering. This work has, among other things, been recognised by Chemistry World selecting Mirkin as ‘Entrepreneur of the year' for 2013.

Source:
rsc.org

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