Home > News > Dose-Dense Chemotherapy Plus Bevacizumab Followed by Nab-Paclitaxel Appears Cardiac Safe in Early-Stage Breast Cancer: Presented at SABCS
December 16th, 2008
Dose-Dense Chemotherapy Plus Bevacizumab Followed by Nab-Paclitaxel Appears Cardiac Safe in Early-Stage Breast Cancer: Presented at SABCS
Abstract:
A dose-dense anthracycline-based therapy that includes bevacizumab followed by nanoparticle albumin-bound paclitaxel (nab-paclitaxel) appears to avoid serious cardiac toxicity in its role as adjuvant treatment for early-stage breast cancer, researchers reported at the 31st Annual San Antonio Breast Cancer Symposium (SABCS).
Heather McArthur, MD, Memorial Sloan-Kettering Cancer Center, New York, New York and colleagues enrolled 80 women with early-stage breast cancer into a trial in which patients were treated with bevacizumab 10 mg/kg administered intravenously every 2 weeks for 8 cycles, concurrently with doxorubicin 60 mg/m2 and cyclophosphamide 600 mg/m2 every 2 weeks for 4 cycles, and then nab-paclitaxel 260 mg/m2 every 2 weeks for 4 cycles. After 8 cycles, for the rest of 1 year, bevacizumab was administered at a dose of 15 mg/kg every 3 weeks. Pegfilgrastim was administered on day 2 of each chemotherapy cycle.
Source:
docguide.com
Bookmark:
| Related News Press |
News and information
Quantum computer improves AI predictions April 17th, 2026
Flexible sensor gains sensitivity under pressure April 17th, 2026
A reusable chip for particulate matter sensing April 17th, 2026
Detecting vibrational quantum beating in the predissociation dynamics of SF6 using time-resolved photoelectron spectroscopy April 17th, 2026
Nanomedicine
A fundamentally new therapeutic approach to cystic fibrosis: Nanobody repairs cellular defect April 17th, 2026
New molecular technology targets tumors and simultaneously silences two ‘undruggable’ cancer genes August 8th, 2025
New imaging approach transforms study of bacterial biofilms August 8th, 2025
Electrifying results shed light on graphene foam as a potential material for lab grown cartilage June 6th, 2025
Announcements
A fundamentally new therapeutic approach to cystic fibrosis: Nanobody repairs cellular defect April 17th, 2026
UC Irvine physicists discover method to reverse ‘quantum scrambling’ : The work addresses the problem of information loss in quantum computing system April 17th, 2026
Events/Classes
Institute for Nanoscience hosts annual proposal planning meeting May 16th, 2025
A New Blue: Mysterious origin of the ribbontail ray’s electric blue spots revealed July 5th, 2024
Researchers demonstrate co-propagation of quantum and classical signals: Study shows that quantum encryption can be implemented in existing fiber networks January 20th, 2023
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||