Home > Press > The role of lipid nanoparticles and its surface modification in reaching the brain: This article by Dr. Manoli Igartua et al. is published in Current Drug Delivery, Volume 15, Issue 9, 2018
 |
Abstract:
Nanomedicine refers to field of science that uses nanotechnology for clinical operations. The use of nanoparticles (NPs) has specially been successful due to their structure. For example, NPs have the ability to cross biological barriers which boosts their effectiveness towards complicated drug delivery problems. This permeability allows NPs to reach biological targets such as brain cells, which would have been impossible by conventional drugs. Due to their effectiveness in this area, NPs have now been prioritized from simply being experimental tests compounds to be used as a workable solution for neurodegenerative disease (ND). NDs, such as Alzheimer's disease and Parkinson's disease are usually correlated with neuronal death, or in other words, the continuous structural and functional neuronal loss.
The role of lipid nanoparticles and its surface modification in reaching the brain: This article by Dr. Manoli Igartua et al. is published in Current Drug Delivery, Volume 15, Issue 9, 2018
Sharjah, U.A.E. | Posted on December 14th, 2018In common ND treatment strategies, one of the hardest obstruction to overcome is low penetration of the drug through the central nervous system (CNS). One of the reasons for this problem is the Blood Brain Barrier (BBB) and Blood Cerebrospinal Fluid Barrier (BCSFB) which protect the brain from invading and unwanted substances. The barriers carry out their function with the help of multispecific transport proteins and detoxifying enzymes. Using nanoparticles opens up many possibilities to counter such obstacles in the NDs treatment as they are proven to effectively deliver drugs to the CNS. The research focuses on the modification of lipid nanoparticles for brain targeting to increase drug efficiency and ability to deliver different kinds of drugs.
In conclusion, it has been difficult to establish which lipid nanoparticle, based on previous tests, was best for ND treatment since the administration route or animal models for each test were different. For the time being, researchers suggest that additional studies and tests are needed to propel research on CNS based drug delivery towards successful brain cell targeting.
####
For more information, please click here
Contacts:
Faizan ul Haq
Copyright © Bentham Science Publishers
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Cancer
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Super-efficient laser light-induced detection of cancer cell-derived nanoparticles: Skipping ultracentrifugation, detection time reduced from hours to minutes! October 6th, 2023
Possible Futures
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
With VECSELs towards the quantum internet Fraunhofer: IAF achieves record output power with VECSEL for quantum frequency converters April 5th, 2024
Nanomedicine
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Discoveries
Chemical reactions can scramble quantum information as well as black holes April 5th, 2024
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Utilizing palladium for addressing contact issues of buried oxide thin film transistors April 5th, 2024
Announcements
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Nanobiotechnology
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||