Home > Press > Peppermint oil and cinnamon could help treat and heal chronic wounds
Peppermint oil (above) and cinnamon are key ingredients in a new wound treatment under development. Credit: matka_Wariatka/iStock/Thinkstock |
Abstract:
Infectious colonies of bacteria called biofilms that develop on chronic wounds and medical devices can cause serious health problems and are tough to treat. But now scientists have found a way to package antimicrobial compounds from peppermint and cinnamon in tiny capsules that can both kill biofilms and actively promote healing. The researchers say the new material, reported in the journal ACS Nano, could be used as a topical antibacterial treatment and disinfectant.
Many bacteria clump together in sticky plaques in a way that makes them difficult to eliminate with traditional antibiotics. Doctors sometimes recommend cutting out infected tissues. This approach is costly, however, and because it's invasive, many patients opt out of treatment altogether. Essential oils and other natural compounds have emerged recently as alternative substances that can get rid of pathogenic bacteria, but researchers have had a hard time translating their antibacterial activity into treatments. Vincent M. Rotello and colleagues wanted to address this challenge.
The researchers packaged peppermint oil and cinnamaldehyde, the compound in cinnamon responsible for its flavor and aroma, into silica nanoparticles. The microcapsule treatment was effective against four different types of bacteria, including one antibiotic-resistant strain. It also promoted the growth of fibroblasts, a cell type that is important in wound healing.
The authors acknowledge funding from Firmenich, the National Institutes of Health and the National Science Foundation.
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About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 158,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
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Contacts:
Vincent M. Rotello, Ph.D.
Department of Chemistry
University of Massachusetts, Amherst
Amherst, MA 01003
General Inquiries:
Michael Bernstein
202-872-6042
Science Inquiries:
Katie Cottingham, Ph.D.
301-775-8455
Copyright © American Chemical Society
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