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Home > Press > How green tea could help improve MRIs

Compounds from green tea could boost the quality of biomedical imaging. 
Credit: pullia/iStock/Thinkstock
Compounds from green tea could boost the quality of biomedical imaging.

Credit: pullia/iStock/Thinkstock

Abstract:
Green tea's popularity has grown quickly in recent years. Its fans can drink it, enjoy its flavor in their ice cream and slather it on their skin with lotions infused with it. Now, the tea could have a new, unexpected role — to improve the image quality of MRIs. Scientists report in the journal ACS Applied Materials & Interfaces that they successfully used compounds from green tea to help image cancer tumors in mice.

How green tea could help improve MRIs

Washington, DC | Posted on March 21st, 2015

Sanjay Mathur and colleagues note that recent research has revealed the potential usefulness of nanoparticles — iron oxide in particular — to make biomedical imaging better. But the nanoparticles have their disadvantages. They tend to cluster together easily and need help getting to their destinations in the body. To address these issues, researchers have recently tried attaching natural nutrients to the nanoparticles. Mathur's team wanted to see if compounds from green tea, which research suggests has anticancer and anti-inflammatory properties, could play this role.

Using a simple, one-step process, the researchers coated iron-oxide nanoparticles with green-tea compounds called catechins and administered them to mice with cancer. MRIs demonstrated that the novel imaging agents gathered in tumor cells and showed a strong contrast from surrounding non-tumor cells. The researchers conclude that the catechin-coated nanoparticles are promising candidates for use in MRIs and related applications.

The authors acknowledge funding from the University of Cologne and the EU Project Nanommune.

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About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 158,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

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Contacts:
Sanjay Mathur, Ph.D.
Institute of Inorganic Chemistry
University of Cologne
Cologne
Germany


General Inquiries
Michael Bernstein

202-872-6042

Science Inquiries
Katie Cottingham, Ph.D.

301-775-8455

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