Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Nanoanalysis Tool Used to Evaluate Hypersensitivity Toothpaste

High magnification FESEM image of dentin treated with Clinpro 5000 after acid challenge. Mineral deposits visibly block the tubules.
(Karlinsey, et al. American Journal of Dentistry (2011) 24; 357)
High magnification FESEM image of dentin treated with Clinpro 5000 after acid challenge. Mineral deposits visibly block the tubules.

(Karlinsey, et al. American Journal of Dentistry (2011) 24; 357)

Abstract:
McCrone Associates, Inc. conducted nanoscale analysis that provided Indiana Nanotech and 3M ESPE with visual proof for patient-reported hypersensitivity benefits of its professional-strength toothpaste.

Nanoanalysis Tool Used to Evaluate Hypersensitivity Toothpaste

Westmont, IL | Posted on February 13th, 2012

Teeth hypersensitivity , is a sharp, momentary pain felt when nerves in the dentin are exposed to stimuli such as hot or cold drinks. Toothpastes that claim to relieve the pain of sensitive teeth are believed to work by blocking the tubules in the dentin that lead to the nerves.

The analysis was published in the December 2011 issue of American Journal of Dentistry by Dr. Robert Karlinsey, Indiana Nanotech's CEO. Dr. Karlinsey discovered that Clinpro toothpaste, which contains a fluoride-compatible tricalcium phosphate system he invented, was the most effective at filling the tubules in a comparison with four leading brands.

With the published findings, the dental community now has visual evidence of Clinpro's patient-reported hypersensitivity benefits.

Dr. Karlinsey's conclusion was made possible by field emission scanning electron microscopy (FESEM) imagery performed at McCrone Associates. It was there that senior research scientist and a co-author of the AJD paper, Craig Schwandt, Ph.D., analyzed demineralized dentin treated with various toothpastes to determine if Clinpro could form mineral deposits in the tubules.

"Craig delivered high quality images," said Dr. Karlinsey. "I loved working with him and I would use McCrone Associates again."

Using FESEM, Dr. Schwandt showed that Clinpro products promoted mineral deposits in the dentin tubules. The deposits were also resistant to acid, which, for instance, can take the form as an acidic beverage like coffee, or be generated as a byproduct of bacteria as it breaks down sugar in the mouth. FESEM also revealed that the other toothpastes only exhibited moderate abilities to block the tubules, and none of their deposits were acid resistant.

"Field emission SEM is an easy and fast way to inspect samples at the nanoscale," said Dr. Schwandt.

####

For more information, please click here

Contacts:
Ken Li
Phone: 312.997.2436

Copyright © McCrone Associates, Inc.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Searching for a nanotech self-organizing principle May 1st, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Imaging

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Bruker Introduces First of Its Kind Dimensional Analysis System: The Novel Contour CMM™ System Fully Integrates 3D Coordinate Measurements with Nanoscale Surface Height, Texture, Waviness and Form Characterization April 26th, 2016

Bruker Introduces Dimension FastScan Pro Industrial AFM: Providing Nanometer-Resolution at High Scan Rates for up to 300-mm Samples April 26th, 2016

Announcements

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

Tools

Exploring phosphorene, a promising new material April 29th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Chemists use DNA to build the world's tiniest thermometer April 27th, 2016

Bruker Introduces Dimension FastScan Pro Industrial AFM: Providing Nanometer-Resolution at High Scan Rates for up to 300-mm Samples April 26th, 2016

Dental

Nano-shells deliver molecules that tell bone to repair itself January 16th, 2016

The artificial materials that came in from the cold: Berkeley Lab researchers develop nature-mimicking freeze-casting technique for fabricating advanced porous materials December 14th, 2015

Graphene oxide could make stronger dental fillings: Study reveals new filling material material that is not toxic to teeth December 4th, 2015

Details from the inner life of a tooth: New X-ray method uses scattering to visualize nanostructures November 21st, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic