Home > Press > Performance of Polymeric Nanoparticles as Gene Carriers Studied by Iranian, Dutch Scientists
Abstract:
A research group consisting of researchers from Royan Biotechnology Research Institute, Tehran and Isfahan Universities of Medical Sciences in cooperation with their colleagues from Medical Research Institute of Utrecht University, Netherlands, studied the performance of a type of polymer as a gene carrier.
Performance of Polymeric Nanoparticles as Gene Carriers Studied by Iranian, Dutch Scientists
Tehran, Iran | Posted on October 9th, 2015The carrier is able to create nanometric particles after being added to the gene pieces and it has been studied at laboratorial scale. It also showed appropriate performance in comparison with the existing commercial samples.
This research deals with the evaluation in vitro gene delivery efficiency of poly [N-(2-aminoethyl) ethylene-imine] (PAEEI). However, the final purpose of the research is to study in vivo gene delivery properties of the polymer. The polymer had been synthesized in the previous studies, but no report is yet available about its gene delivery properties.
The application of virus gene carriers is very efficient but there are limitations in the applications due to the malfunction in their immunity after continuous consumptions. Therefore, non-virus delivery systems have been of more interest in recent years. Cationic polymers, inorganic nanoparticles, lipid nanoparticles, liposomes, and peptides are among the non-virus gene delivery systems.
The pre-cursor monomer was firstly synthesized in this research. Then, gene delivery properties and the toxicity of the monomer were studied on living cells at laboratorial scale. In the end, it was concluded that the suggested polymer is comparable to and can replace the standard sample.
Results of the research have been published in Journal of Pharmacy & Pharmaceutical Sciences, vol. 17, issue 4, 2014, pp. 461-474.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
News and information
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Nanomedicine
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Discoveries
Chemical reactions can scramble quantum information as well as black holes April 5th, 2024
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Utilizing palladium for addressing contact issues of buried oxide thin film transistors April 5th, 2024
Materials/Metamaterials/Magnetoresistance
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Focused ion beam technology: A single tool for a wide range of applications January 12th, 2024
Announcements
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Nanobiotechnology
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Research partnerships
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Researchers’ approach may protect quantum computers from attacks March 8th, 2024
'Sudden death' of quantum fluctuations defies current theories of superconductivity: Study challenges the conventional wisdom of superconducting quantum transitions January 12th, 2024
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||