Home > Press > Tracking Gold Nanoparticles in the Body: Where Do They Go?
![]() |
Abstract:
Ivan M. Kempson et al. have investigated the intravenous delivery and excretion of polyethylene glycol (PEG)-coated gold nanoparticles (GNPs) in the whiskers and at the pilosebaceous unit in a mouse model. The use of X-ray fluorescence allowed visualisation of this deposition and, after 14 days, gold bands could be visualised in the hairs, the pharmacokinetic profiles of which indicated the blood concentration kinetics.
This deposition of nanoparticles was found to take place intermittently during this 14 day period, so demonstrating the prolonged mobility of these nanoparticles within the body. Furthermore, confocal microscopy was used to make a 3D reconstruction of nanoparticle distribution leading to identification of nanoparticle aggregates within the medullary canal.
These results are of interest in understanding the fate and excretion of nanoparticles from the body. Also, due to the successful elucidation of kinetic information from hair samples, this illustrates the potential for testing the nanoparticle load in the body via hair sampling as oppose to blood sampling.
####
For more information, please click here
Copyright © Wiley-VCH Materials Science Journals
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related Links |
Link to the original paper on Wiley Online Library:
Related News Press |
News and information
Flexible electronics integrated with paper-thin structure for use in space January 17th, 2025
Quantum engineers ‘squeeze’ laser frequency combs to make more sensitive gas sensors January 17th, 2025
Nanomedicine
Exosomes: A potential biomarker and therapeutic target in diabetic cardiomyopathy November 8th, 2024
Unveiling the power of hot carriers in plasmonic nanostructures August 16th, 2024
Discoveries
Quantum engineers ‘squeeze’ laser frequency combs to make more sensitive gas sensors January 17th, 2025
Announcements
Quantum engineers ‘squeeze’ laser frequency combs to make more sensitive gas sensors January 17th, 2025
The National Space Society Congratulates SpaceX on Starship’s 7th Test Flight: Latest Test of the Megarocket Hoped to Demonstrate a Number of New Technologies and Systems January 17th, 2025
Safety-Nanoparticles/Risk management
Tests find no free-standing nanotubes released from tire tread wear September 8th, 2023
Billions of nanoplastics released when microwaving baby food containers: Exposure to plastic particles kills up to 75% of cultured kidney cells July 21st, 2023
![]() |
||
![]() |
||
The latest news from around the world, FREE | ||
![]() |
![]() |
||
Premium Products | ||
![]() |
||
Only the news you want to read!
Learn More |
||
![]() |
||
Full-service, expert consulting
Learn More |
||
![]() |