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November 21st, 2007
The changing color of gold
Abstract:
The copper ion Cu2+ is essential in biochemistry but can be toxic in high concentrations. Now, thanks to work by two chemists in the US, it can be detected with greater sensitivity ("Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles").
Cu2+ has so far proved challenging to detect using conventional fluorescent sensors due to its quenching effect on fluorophores. To overcome this problem, Juewen Liu and Yi Lu at the University of Illinois at Urbana-Champaign used a colour change that takes place in a solution of gold nanoparticles as a selective and sensitive Cu2+ sensor.
Source:
nanowerk.com
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