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July 5th, 2007
Nanoparticles get a free ride
Abstract:
A breakthrough discovery in the US could see nanoparticles hitching a ride on red blood cells to become an ultimate drug delivery mechanism.
Nanoparticles have long been seen as a promising frontier for intravascular drug delivery but advances in the technology have been limited by the problem that nanoparticles are quickly removed from the blood rendering them ineffective in delivering drugs.
But researchers at the University of California, Santa Barbara, have found a solution to the problem - attaching nanoparticles to the surface of red blood cells (RBCs) dramatically increases the in vivo lifetime of the nanoparticles.
Source:
in-pharmatechnologist.com
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