Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Imec and PEIRA develop platform for in-vitro study of brain tissue

Innovative slice-tilting instrument for in-vitro research on brain tissue developed by imec and Peira
Innovative slice-tilting instrument for in-vitro research on brain tissue developed by imec and Peira

Abstract:
The nanoelectronics research centre imec and Peira, a Belgium-based manufacturer of pharmaceutical and chemical research instruments, jointly developed an innovative slice-tilting instrument for in-vitro research on brain tissue. The new tool enables long-term studying of brain cultures through electronic stimulation and read-out, essential in getting insight into the functioning of the brain.

Imec and PEIRA develop platform for in-vitro study of brain tissue

Düsseldorf, Germany | Posted on November 17th, 2010

To increase knowledge on neuronal networks, on how our brain works, and on the cellular processes causing neurodegenerative diseases such as Alzheimer's disease, brain tissue slices need to be investigated for a longer time. To keep brain tissue slices alive to study long-term effects in neuronal circuits, the slices have to be cultured. They have to attach to a substrate and start growing. Such a brain tissue culturing procedure is as a very difficult and precise manipulation, and it is believed to be one of the most challenging cultures known in the medical world. Therefore, imec has developed together with Peira, a custom slice-tilting device containing up to 16 chips with stimulation and read-out electronics, especially customized to grow brain slice tissue on. The tilting device is fully incorporated in a cell growth incubator. Parameters such as tilting angle, speed and interval time can be programmed to obtain optimal growth, survival and functionality of the brain slice. The new tool ensures optimal growth of brain slices on the chips for more than a month. It enables in-vitro investigation of long-term processes in brain circuits.

"With its research into lab and preclinical instrumentation, imec aims to play an important role in developing powerful healthcare diagnostics and therapy," says Kris Verstreken, Program Director Life Sciences at imec. Imec's experience in nano- and microsystems technology is at the basis of innovative devices and instruments for the pharmaceutical industry. Imec has been developing novel techniques and protocols for brain slice culturing on multi-electrode array and microchip surfaces. Part of this innovation is the concept for a new slice tilter device for the culturing process. "This in-vitro brain tissue research instrument is an example of how our technology can support medical research into areas such as neurology, cardiology or oncology, interacting not only at the level of the individual cell but also capturing the complexity of cellular networks, tissues or organs. For the practical implementation of the slice tilter device, imec and Peira have joined forces."

"We share a believe at Peira that breakthrough research will often need novel and unique instruments to create new insights," says Hans Nicasy, founder and managing director at Peira. This brain tissue instrument is a nice illustration of how Peira solves the researcher's problem by integrating good engineering practices into an efficient and effective apparatus. The slice tilter platform was developed in close cooperation between the researchers at imec and Peira's engineers. Peira supplies scientists in academia and the biotech and pharmaceutical industries with innovative instruments and co-develops customized research platforms that help to create new insights in the pathways of neuro diseases such Alzheimer and Parkinson or help to develop new cancer diagnostics or therapy tools."

####

About imec
Imec performs world-leading research in nanoelectronics. Imec leverages its scientific knowledge with the innovative power of its global partnerships in ICT, healthcare and energy. Imec delivers industry-relevant technology solutions. In a unique high-tech environment, its international top talent is committed to providing the building blocks for a better life in a sustainable society. Imec is headquartered in Leuven, Belgium, and has offices in Belgium, the Netherlands, Taiwan, US, China and Japan. Its staff of more than 1,750 people includes over 550 industrial residents and guest researchers. In 2009, imec's revenue (P&L) was 275 million euro. Further information on imec can be found at www.imec.be.

NOTE: Imec is a registered trademark for the activities of IMEC International (a legal entity set up under Belgian law as a "stichting van openbaar nut”), imec Belgium (IMEC vzw supported by the Flemish Government), imec the Netherlands (Stichting IMEC Nederland, part of Holst Centre which is supported by the Dutch Government), imec Taiwan (IMEC Taiwan Co.) and imec China (IMEC Microelectronics (Shangai) Co. Ltd.).

About Peira
Peira is a technology provider/integrator and ‘applied science’ partner for life science groups who want to build new, innovative research or proof of principle set ups. The company has industrial experience in developing tools for pharmaceutical development activities, in vivo/ex vivo and in vitro experimental set ups and imaging automation for researchers in several therapeutic areas, such as neuroscience and oncology.

Peira is offering ‘productizing services’ for research organizations active in the field of nano electronics and nano-technology and builds customized research platforms for academia, the biotech and the pharmaceutical industry. Peira is headquartered in Beerse, Belgium. More information can be found on www.peira.be.

For more information, please click here

Contacts:
imec
Hanne Degans
Imec External Communications Officer
T: +32 16 28 17 69
M: +32 486 065 175


Barbara Kalkis
Maestro Marketing & PR, for Imec
T: +1 408 996 9975
M: +1 408 529 4210


Peira
Miranda Woestenborghs
Administration Support
T + 32 14 600 800

Copyright © imec

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Global Nano-Enabled Packaging Market For Food and Beverages Will Reach $15.0 billion in 2020 May 26th, 2015

Dr.Theivasanthi Slashes the Price of Graphene Heavily: World first & lowest price – Nano-price (30 USD / kg) of graphene by nanotechnologist May 26th, 2015

Fine-tuned molecular orientation is key to more efficient solar cells May 26th, 2015

DNA Double Helix Does Double Duty in Assembling Arrays of Nanoparticles: Synthetic pieces of biological molecule form framework and glue for making nanoparticle clusters and arrays May 25th, 2015

Nanoelectronics

One step closer to a single-molecule device: Columbia Engineering researchers first to create a single-molecule diode -- the ultimate in miniaturization for electronic devices -- with potential for real-world applications May 25th, 2015

Basel physicists develop efficient method of signal transmission from nanocomponents May 23rd, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Random nanowire configurations increase conductivity over heavily ordered configurations May 16th, 2015

Announcements

Global Nano-Enabled Packaging Market For Food and Beverages Will Reach $15.0 billion in 2020 May 26th, 2015

Dr.Theivasanthi Slashes the Price of Graphene Heavily: World first & lowest price – Nano-price (30 USD / kg) of graphene by nanotechnologist May 26th, 2015

Fine-tuned molecular orientation is key to more efficient solar cells May 26th, 2015

DNA Double Helix Does Double Duty in Assembling Arrays of Nanoparticles: Synthetic pieces of biological molecule form framework and glue for making nanoparticle clusters and arrays May 25th, 2015

Tools

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Nanometrics Announces Live Webcast of Upcoming Investor and Analyst Day May 20th, 2015

Taking control of light emission: Researchers find a way of tuning light waves by pairing 2 exotic 2-D materials May 20th, 2015

DELMIC announces a workshop hosted by Phenom World on Integrated CLEM to be held on Wednesday June 24th at the Francis Crick Institute (Lincoln Inn Fields Laboratory). May 19th, 2015

Alliances/Partnerships/Distributorships

Samtec, Global Provider of Interconnect Systems, Joins IRT Nanoelec Silicon Photonics Program May 21st, 2015

SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium: May 20th, 2015

Industrial Nanotech, Inc. Announces Official Launch of the Eagle Platinum Tile™ May 19th, 2015

DiATOME enables surface preparation for AFM and FIB May 19th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project