Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > Bruker Light-Sheet Microscopes at Major Comprehensive Cancer Center: New Advanced Imaging Center Powered by Two MuVi and LCS SPIM Microscopes

MuVi SPIM Multiview light-sheet microscope for live samples.
MuVi SPIM Multiview light-sheet microscope for live samples.

Abstract:
Bruker Corporation (Nasdaq: BRKR), a leading supplier of single-plane illumination microscopy (SPIM) technology for research on live cells and cleared biological samples, today announced that two Luxendo MuVi™ and LCS SPIM™ light-sheet microscopes have been installed by Memorial Sloan Kettering Cancer Center (MSK). The funding for the two light-sheet fluorescence microscopes was supported by Cycle for Survival ( https://www.cycleforsurvival.org ). The new SPIM microscopes will help researchers visualize the cellular and tissue hallmarks of cancer and translate those findings into better cancer treatment methods.

Bruker Light-Sheet Microscopes at Major Comprehensive Cancer Center: New Advanced Imaging Center Powered by Two MuVi and LCS SPIM Microscopes

New York, NY | Posted on March 25th, 2021

“By understanding how cells mobilize to build organs, researchers can glean insights into why some cells become cancerous and lead to organ destruction,” said Dr. Anna-Katerina Hadjantonakis, MSK Chair of the Developmental Biology Program. “Instruments such as these are useful for imaging across differing length scales — from subcellular to single cells to tissue-level processes — allowing researchers to study cellular dynamics and cellular motion, processes that enable cells to metastasize.”



“Light-sheet fluorescence microscopy has emerged as a uniquely powerful method for high-resolution, cleared-sample and dynamic biological imaging,” added Dr. Lars Hufnagel, Vice President and General Manager of Bruker’s Luxendo light-sheet microscopy business. “We couldn’t be more pleased that our technology will be assisting the great MSK researchers and programs in such important work.”



About the MuVi and LCS SPIM Systems

Bruker’s SPIM systems avoid sample phototoxicity by sequentially illuminating a stack of small slices of the organism, allowing scientists to observe living organisms for extended periods of time without photodamage. In particular, MuVi SPIM allows fast 3D imaging of live cells and living objects, such as spheroids and whole specimens, without the need of sample rotation. Despite the fact that sample rotation is not necessarily needed for a non-isotropic acquisition, the MuVi SPIM system provides this degree of freedom such that isotropic resolution can be achieved.



The modular LCS SPIM for large, cleared samples has been designed to be compatible with a broad variety of clearing solutions and sample sizes. Its new sample mounting approach and innovative optical design enables unprecedented acquisition times and minimizes sample distortions while seamlessly integrating into existing clearing and sample preparation pipelines. To handle the vast amount of data produced by the light-sheet technique, Lux DATA comprehensive data processing and storage provides fast transfer and large-capacity storage and leverages multi-core- and multi-GPU-based processing.

####

About Bruker Corporation
Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high performance scientific instruments and high value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular and cell biology research, in applied and pharma applications, in microscopy and nanoanalysis, as well as in industrial applications. Bruker offers differentiated, high-value life science and diagnostics systems and solutions in preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology, functional structural and condensate biology, as well as in clinical microbiology and molecular diagnostics.

For more information, please click here

Contacts:
Investor Contact:

Miroslava Minkova

Director of Investor Relations & Corporate Development

T: +1 (978) 663-3660, ext. 1479

E:



Media Contact:

Stephen Hopkins

Content Marketing Manager

Bruker Nano Fluorescence Microscopy

T: +1 (520) 741-1044 x1022

E:

Copyright © Bruker Corporation

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Antibody binding-site conserved across COVID-19 virus variants: The structural revelation could have implications as a therapeutic target in all SARS-CoV-2 variants April 9th, 2021

Discovery could help lengthen lifespan of electronic devices: The research could lead to electronics being designed with better endurance April 9th, 2021

Graphene: Everything under control: Research team demonstrates control mechanism for quantum material April 9th, 2021

Energy transmission by gold nanoparticles coupled to DNA structures April 9th, 2021

Imaging

Oxford Instruments Asylum Research Releases Variable Magnetic Field Module accessory for Jupiter XR, Large Sample Atomic Force Microscope March 26th, 2021

Microscope that detects individual viruses could power rapid diagnostics March 19th, 2021

Targeting Cancer Detection & Identification of Microorganisms, CEA-Leti Develops Mid-Infrared, Spectral-Imaging Technique: Presentations at Photonics West 2021 Show How Early-Stage Imaging System’s Flexibility Can Be Applied Broadly in Medical Field March 18th, 2021

Engineering the boundary between 2D and 3D materials: Cutting-edge microscope helps reveal ways to control the electronic properties of atomically thin materials February 26th, 2021

Announcements

Discovery could help lengthen lifespan of electronic devices: The research could lead to electronics being designed with better endurance April 9th, 2021

Graphene: Everything under control: Research team demonstrates control mechanism for quantum material April 9th, 2021

Energy transmission by gold nanoparticles coupled to DNA structures April 9th, 2021

A new agent for the brain diseases: mRNA April 9th, 2021

Tools

Knowledge and Power: Oxford Instruments Plasma Technology and LayTec join forces to provide critical front end processing solutions for the production of compound semiconductor devices April 7th, 2021

Oxford Instruments Asylum Research Releases Variable Magnetic Field Module accessory for Jupiter XR, Large Sample Atomic Force Microscope March 26th, 2021

Izon Science launches the Exoid to transform nanoparticle measurement: The semi-automated Exoid device uses new-generation Tunable Resistive Pulse Sensing (TRPS) technology, enabling the measurement of complex nano-particle size, concentration, and charge – with unparalleled prec March 23rd, 2021

Microscope that detects individual viruses could power rapid diagnostics March 19th, 2021

New-Contracts/Sales/Customers

Arrowhead Pharmaceuticals Announces Closing of Agreement with Takeda November 27th, 2020

Veeco Announces Aledia Order of 300mm MOCVD Equipment for microLED Displays: Propel™ Platform First 300mm System with EFEM Designed for Advanced Display Applications October 20th, 2020

GREENWAVES TECHNOLOGIES Announces Next Generation GAP9 Hearables Platform Using GLOBALFOUNDRIES 22FDX Solution October 16th, 2020

Bruker Launches Advanced In-Situ Nanomechanical Test Instrument for Analyzing Materials Deformation in Electron Microscopes: Hysitron PI 89 SEM PicoIndenter Offers Unprecedented Range and Flexibility October 15th, 2020

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project