Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Shining a light on tiny polymer shapes: Visiting graduate student studies high-throughput manufacturing of precisely shaped microparticles

Shown here are examples of micro shapes polymerized by ultraviolet light in polyethylene glycol diacrylate (PEG-DA).
Image courtesy of Ryan Oliver/Mechanosynthesis Group
Shown here are examples of micro shapes polymerized by ultraviolet light in polyethylene glycol diacrylate (PEG-DA).

Image courtesy of Ryan Oliver/Mechanosynthesis Group

Abstract:
Ryan Oliver, a visiting graduate student in the lab of associate professor of mechanical engineering A. John Hart, is developing a technique called maskless fluidic lithography that creates unique shapes in a liquid polymer by exposing it to patterned ultraviolet light, a process known as photopolymerization.

Shining a light on tiny polymer shapes: Visiting graduate student studies high-throughput manufacturing of precisely shaped microparticles

Cambridge, MA | Posted on February 11th, 2014

For example, Oliver uses a projector to pattern shapes in polyethylene glycol diacrylate (PEG-DA), a common biocompatible polymer. Unlike semiconductor processing, which uses wafer masks produced as single-use items, the integrated projection system allows for rapid change of the pattern.

Key to the system is a Texas Instruments digital micromirror device (DMD) that can turn micromirrors on and off 32,552 times a second. "Because the mirrors are so fast, we can make decisions very quickly, which is hard to do with a masked system," Oliver says. "You would spend several days ordering or fabricating a mask rather than milliseconds if you needed a new pattern." By controlling how long each mirror is switched on during a single second, the system varies the intensity of the projection to form two-dimensional or three-dimensional structures. Oliver likens the process to layer-by-layer assembly in a single step.

Ryan and Hart chose the stop-flow lithography approach, inspired by research from Professor Patrick Doyle's group at MIT, while they were at the University of Michigan as a platform for studying the manufacture of large quantities of custom microparticles. Their vision is to use particles that are designed to work together and act as a sensitive biosensor. To realize the vision, Ryan has a goal to produce microparticles from about 250 nanometers to about 100 microns in a library of shapes such as diamonds, triangles, squares, and octagons. "We're exploring methods of taking them down to the nanoscale, but the current system produces microparticles," Oliver says. "What sets this method apart is, one, high throughput; two, flexibility using the DMD chip; and three, the fact that you can control the shape as well as the size of the particles, and possibly the chemistry."

Oliver is studying how to manipulate a collection of polymer particles on a liquid surface in order to assemble them in specific ways. "We needed a platform in order to synthesize microparticles that we could perform self-assembly experiments on, because that promises to allow us to build sensors that we can't build now, that are too complex — they're made out of too many types of materials to fabricate using traditional manufacturing methods," Oliver says. "A lot of applications may require control over the shape, the surface finish, the chemistry, and the size of microparticles, so we've been exploring this as a method toward that end, as well as understanding how to improve the shape accuracy while increasing throughput."

Such templated polymers can be used for a range of processes, from drug delivery to cell culture assays to casting molds. Researchers in Hart's Mechanosynthesis Lab also adapted the ultraviolet-light-based polymerization to a roll-to-roll system in addition to the microfluidic system.

One drawback with PEG, which is a hydrogel, is that it readily absorbs water, so it can swell or change shape in wet environments.

"Beyond the manufacturing process, we are interested in secondary means to assemble the particles into complex, hierarchical structures, such as those including cells," Oliver says. "These assemblies could be very useful for performing high-throughput bioassays or building novel tissue-like structures."

Oliver followed Hart to MIT from the University of Michigan. He led work on the Robofurnace project, an automated bench-top chemical vapor deposition system for growing carbon nanotubes and other nanomaterials. He hopes to finish his PhD through Michigan in August. His dissertation will focus on a suite of tools for high-throughput polymer micromanufacturing and manipulation, including the direct-write fluidic lithography method. Oliver presented his work on polymers at a Materials Research Society meeting and at the Enabling Nanofabrication for Rapid Innovation workshop in 2013.

Denis Paiste
Materials Processing Center

####

For more information, please click here

Copyright © Massachusetts Institute of Technology

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Oxford Instruments’ Triton Cryofree dilution refrigerator selected by Oxford University for developing scalable quantum nanodevices September 2nd, 2015

JEOL Introduces New Best-in-Class Field Emission SEM September 2nd, 2015

TCL and QD Vision Demonstrate the Future of Wide Color Gamut Television at IFA: Color IQ Based Display is the First Commercially-Branded Television to Present Over 90% of ITU Rec. 2020 Color Gamut September 2nd, 2015

Atomic Force Microscopes from Asylum Research Guide the Development of Thin Film Deposition and Etch Processes September 2nd, 2015

Microfluidics/Nanofluidics

Smart hydrogel coating creates 'stick-slip' control of capillary action July 27th, 2015

Miniature Technology, Large-Scale Impact: Winner of the 2015 Lindros Award for translational medicine, Kjeld Janssen is pushing the boundaries of the emerging lab-on-a-chip technology July 7th, 2015

Lehigh University researchers unveil engineering innovations at TechConnect 2015: TechConnect is the world's largest accelerator for industry-vetted emerging-technologies ready for commercialization June 11th, 2015

How to cut a vortex into slices: A group of physicists, lead by Olga Vinogradova, professor at the Lomonosov Moscow State University, came up with a way to stir up a liquid in the microchannel June 3rd, 2015

Academic/Education

Sustainable nanotechnology center September 1st, 2015

National Science Foundation Selects SUNY Poly CNSE for Expanded $2.1M Northeast Advanced Technological Education Center: NSF Center Locates to NanoCollege in Support of Flourishing Tech Industry in NYS September 1st, 2015

Announcing Oxford Instruments and School of Physics signing a Memorandum of Understanding August 26th, 2015

Kwansei Gakuin University in Hyogo, Japan, uses Raman microscopy to study crystallographic defects in silicon carbide wafers August 25th, 2015

Self Assembly

Using DNA origami to build nanodevices of the future September 1st, 2015

Louisiana Tech University researchers discover synthesis of a new nanomaterial: Interdisciplinary team creates biocomposite for first time using physiological conditions August 24th, 2015

Novel nanostructures for efficient long-range energy transport August 21st, 2015

Biophysics: Formation of swarms in nanosystems August 18th, 2015

Materials/Metamaterials

Sustainable nanotechnology center September 1st, 2015

Using ultrathin sheets to discover new class of wrapped shapes: UMass Amherst materials researchers describe a new regime of wrapped shapes August 31st, 2015

An engineered surface unsticks sticky water droplets August 31st, 2015

New material science research may advance tech tools August 31st, 2015

Announcements

For 2-D boron, it's all about that base: Rice University theorists show flat boron form would depend on metal substrates September 2nd, 2015

Silk bio-ink could help advance tissue engineering with 3-D printers September 2nd, 2015

Phagraphene, a 'relative' of graphene, discovered September 2nd, 2015

A marine creature's magic trick explained: Crystal structures on the sea sapphire's back appear differently depending on the angle of reflection September 2nd, 2015

Tools

Oxford Instruments’ Triton Cryofree dilution refrigerator selected by Oxford University for developing scalable quantum nanodevices September 2nd, 2015

JEOL Introduces New Best-in-Class Field Emission SEM September 2nd, 2015

Atomic Force Microscopes from Asylum Research Guide the Development of Thin Film Deposition and Etch Processes September 2nd, 2015

Nanolab Technologies LEAPS Forward with High-Performance Analysis Services to the World: Nanolab Orders Advanced Local Electrode Atom Probe (LEAP®) Microscope from CAMECA Unit of AMETEK Materials Analysis Division August 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic