Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Smart Coating Opens Door To Safer Hip, Knee and Dental Implants

Cross-sectional transmission electron microscope image of the functionally graded smart coating with nano-silver particles distributed throughout the entire thickness of the coating.
Cross-sectional transmission electron microscope image of the functionally graded smart coating with nano-silver particles distributed throughout the entire thickness of the coating.

Abstract:
Researchers at North Carolina State University have developed a "smart coating" that helps surgical implants bond more closely with bone and ward off infection.

Smart Coating Opens Door To Safer Hip, Knee and Dental Implants

Raleigh, NC | Posted on February 3rd, 2010

When patients have hip, knee or dental replacement surgery, they run the risk of having their bodies reject the implant. But the smart coating developed at NC State mitigates that risk by fostering bone growth into the implant. The coating creates a crystalline layer next to the implant, and a mostly amorphous outer layer that touches the surrounding bone. The amorphous layer dissolves over time, releasing calcium and phosphate, which encourages bone growth.

"The bone grows into the coating as the amorphous layer dissolves, resulting in improved bonding, or osseointegration," says Dr. Afsaneh Rabiei, an NC State associate professor of mechanical and aerospace engineering, associate faculty member of biomedical engineering and co-author of a paper describing the research. This bonding also makes the implant more functional, because the bonding helps ensure that the bone and the implant do a better job of sharing the load.

"We call it a smart coating because we can tailor the rate at which the amorphous layer dissolves to match the bone growth rate of each patient," Rabiei says. This is important because people have very different rates of bone growth. For example, young people's bones tend to grow far faster than the bones of older adults.

The researchers have also incorporated silver nanoparticles throughout the coating to ward off infections. Currently, implant patients are subjected to an intense regimen of antibiotics to prevent infection immediately following surgery. However, the site of the implant will always remain vulnerable to infection. But by incorporating silver into the coating, the silver particles will act as antimicrobial agents as the amorphous layer dissolves, Rabiei says. This will not only limit the amount of antibiotics patients will need following surgery, but will provide protection from infection at the implant site for the life of the implant. Moreover, the silver is released more quickly right after surgery, when there is more risk of infection, due to the faster dissolution of the amorphous layer of the coating. Silver release will slow down while the patient is healing. "That is another reason why we call it smart coating," Rabiei says.

The research was funded by the National Science Foundation, and was accomplished with assistance from the Center for Nanophase Materials Sciences and Shared Research Equipment User Facilities at Oak Ridge National Laboratory.

The research, "Functionally graded hydroxyapatite coatings doped with antibacterial components," was co-authored by Rabiei, former NC State Ph.D. student Xiao Bai, and Oak Ridge National Laboratory researchers Karren More and Christopher Rouleau. The research is published online by Acta BioMaterialia.

####

About North Carolina State University
With more than 31,000 students and nearly 8,000 faculty and staff, North Carolina State University is a comprehensive university known for its leadership in education and research, and globally recognized for its science, technology, engineering and mathematics leadership.

NC State students, faculty and staff are focused. As one of the leading land-grant institutions in the nation, NC State is committed to playing an active and vital role in improving the quality of life for the citizens of North Carolina, the nation and the world.

For more information, please click here

Contacts:
Matt Shipman
News Services
919.515.6386

Dr. Afsaneh Rabiei
919.513.2674

Copyright © North Carolina State University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

UK NANOSAFETY GROUP publishes 2nd Edition of guidance to support safe working with nanomaterials May 30th, 2016

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Govt.-Legislation/Regulation/Funding/Policy

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Doubling down on Schrödinger's cat May 27th, 2016

Harnessing solar and wind energy in one device could power the 'Internet of Things' May 26th, 2016

Thermal modification of wood and a complex study of its properties by magnetic resonance May 26th, 2016

Possible Futures

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Doubling down on Schrödinger's cat May 27th, 2016

Nanomedicine

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Supercrystals with new architecture can enhance drug synthesis May 24th, 2016

Announcements

UK NANOSAFETY GROUP publishes 2nd Edition of guidance to support safe working with nanomaterials May 30th, 2016

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Nanobiotechnology

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Supercrystals with new architecture can enhance drug synthesis May 24th, 2016

Dental

Nano-shells deliver molecules that tell bone to repair itself January 16th, 2016

The artificial materials that came in from the cold: Berkeley Lab researchers develop nature-mimicking freeze-casting technique for fabricating advanced porous materials December 14th, 2015

Graphene oxide could make stronger dental fillings: Study reveals new filling material material that is not toxic to teeth December 4th, 2015

Details from the inner life of a tooth: New X-ray method uses scattering to visualize nanostructures November 21st, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic