Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Prize winning research could bring relief to 3.5 million denture stomatitis (oral thrush) sufferers

Abstract:
A research project undertaken at Liverpool University, which has the potential to bring relief to the estimated 3.5 million UK sufferers of oral thrush, has won the £25,000 Armourers & Brasiers Venture Prize. This will allow the project to proceed to clinical evaluation.

Prize winning research could bring relief to 3.5 million denture stomatitis (oral thrush) sufferers

London, UK | Posted on June 14th, 2009

According to the most recent adult dental survey, 28 percent of the UK population wears dentures and a quarter of these are likely to develop denture stomatitis or fungal induced stomatitis (mainly Candida albicans), commonly known as oral thrush. This is a significant problem for denture wearers and is seemingly on the increase.

The Armourers & Brasiers Venture Prize, which is awarded annually in the form of an investment, enables the winner to engage in the early commercialisation of promising research and has been won by a team of scientists from the University of Liverpool. This team is led by senior lecturer and materials scientist, Dr Rachel Williams, and senior lecturer in oral surgery, Dr Luke Dawson.

The project's idea is based on a cost effective nanoparticle silica coating which inhibits the adhesion and proliferation of cells and micro-organisms. Laboratory tests show that the nanoparticulate silica coating can inhibit the build up of virulent oral thrush (Candida albicans). Using Proof of Concept (POC) funds awarded by the University technology transfer company, Ulive, the team has developed a transparent solution containing the nanoparticles with adhesive patches on each particle which promote attachment to the denture. This solution can be used by denture wearers as part of their normal cleaning procedure and provides a renewable, tasteless nanoparticulate coating on the dentures which will prevent oral thrush infections.

"Our approach will reduce the need for sufferers of oral thrush to be treated by drug therapy. This is important as these drugs cannot be used in all patients", said Dr Williams. "Our product aims to prevent the occurrence of oral thrush and maintain a healthy mouth via continual renewal of the nanoparticle coating."

"Having proved the principle in the laboratory using the Ulive POC funding we now need to assess this product in a clinical setting," continued Dr Williams. "The prize win will go towards carrying out clinical trials and evaluation in key patient groups."

"This product is a very worthy winner," explained Professor Bill Bonfield chairman of the Armourers & Brasiers Venture Prize judging panel. "Our aim is to stimulate and encourage British based materials science development and Dr Williams and her team is, by exploiting materials technology that inhibits cell-surface interactions, using a science that will have a highly significant bearing on the development of materials and surfaces in healthcare."

Alongside Professor Bonfield on the judging panel were Cambridge based materials scientist Professor Colin Humphreys, representatives from First Ventures which invests and advises high potential technology companies and Members of the Armourers & Brasiers Company.

"We see significant potential for this product as a regular denture cleaning product," said Dr Williams. "Worldwide market opportunities are significant especially in the developed world due to an aging population leading to an increasing number of denture wearers."

The Liverpool University team comprises Dr Rachel Williams (lead; School of Clinical Sciences), Dr Luke Dawson (School of Dental Sciences), colloid scientist Dr. Mike Garvey (Department of Physics), microbiologist Dr. Heather Allison (School of Biological Sciences) and business manager Dr. Gillian Murray (Ulive Enterprises)

####

About Liverpool University
The University of Liverpool is a world leading research university. Its history dates back to 1881 and the establishment of University College Liverpool.
The Victoria Building

Liverpool is the original redbrick university. The term 'redbrick' was inspired from the iconic Victoria Building, completed in 1892.

Today, the University continues to expand its teaching and research with centres of excellence in areas such as medicine, engineering and veterinary science. It is a member of the Russell Group, the association of the UK's top 20 research-led universities.

For more information, please click here

Contacts:
Peter Scaramanga
+44 1342 316193

Copyright © Liverpool University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Ultrasonic Waves Applied in Production of Graphene Nanosheets August 20th, 2014

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Success in Intracellular Imaging of Cesium Distribution in Plants Used for Cesium Absorption August 19th, 2014

Nanomedicine

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Graphene rubber bands could stretch limits of current healthcare, new research finds August 19th, 2014

Interaction between Drug, DNA for Designing Anticancer Drugs Studied in Iran August 17th, 2014

Iranian Scientists Stabilize Protein on Highly Stable Electrode Surface August 14th, 2014

Discoveries

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Ultrasonic Waves Applied in Production of Graphene Nanosheets August 20th, 2014

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Electrical engineers take major step toward photonic circuits: Team invents non-metallic metamaterial that enables them to 'compress' and contain light August 19th, 2014

Announcements

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Ultrasonic Waves Applied in Production of Graphene Nanosheets August 20th, 2014

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Electrical engineers take major step toward photonic circuits: Team invents non-metallic metamaterial that enables them to 'compress' and contain light August 19th, 2014

Dental

New Powder Nanocomposite Miracle in Bone Recovery May 10th, 2014

Newly-Produced Bone Cement Able to Carry Medicine April 21st, 2014

Plasma tool for destroying cancer cells: Inducing biological tissue damage with an atmospheric pressure plasma source could open the door to many applications in medicine March 26th, 2014

Scientists develop world’s first light-activated antimicrobial surface that also works in the dark March 24th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE