Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Tiny 'lab-on-a-chip' detects pollutants, disease and biological weapons

This is Yosi Shacham-Diamand of Tel Aviv University.

Credit: AFTAU
This is Yosi Shacham-Diamand of Tel Aviv University.
Credit: AFTAU

Abstract:
Tel Aviv University scientists develop highly accurate nano-scale biomonitoring solution

Tiny 'lab-on-a-chip' detects pollutants, disease and biological weapons

New York, NY and Tel Aviv, Israel | Posted on March 1st, 2009

For centuries, animals have been our first line of defense against toxins. A canary in a coalmine served as a living monitor for poisonous gases. Scientists used fish to test for contaminants in our water. Even with modern advances, though, it can take days to detect a fatal chemical or organism.

Until now. Working in the miniaturized world of nanotechnology, Tel Aviv University researchers have made an enormous -- and humane -- leap forward in the detection of pollutants.

A team led by Prof. Yosi Shacham-Diamand, vice-dean of TAU's Faculty of Engineering, has developed a nano-sized laboratory, complete with a microscopic workbench, to measure water quality in real time. Their "lab on a chip" is a breakthrough in the effort to keep water safe from pollution and bioterrorist threats, pairing biology with the cutting-edge capabilities of nanotechnology.

"We've developed a platform -- essentially a micro-sized, quarter-inch square 'lab' -- employing genetically engineered bacteria that light up when presented with a stressor in water," says Prof. Shacham-Diamand. Equipment on the little chip can work to help detect very tiny light levels produced by the bacteria.

Instead of using animals to help detect threats to a water supply, Prof. Shacham-Diamand says "Our system is based on a plastic chip that is more humane, much faster, more sensitive and much cheaper."

Tiny Lab-on-Chip Boosts Accuracy

"Basically, ours is an innovative advance in the 'lab on a chip' system," says Prof. Shacham-Diamand. "It's an ingenious nano-scale platform designed to get information out of biological events. Our solution can monitor water with never-before-achieved levels of accuracy. But as a platform, it can also be used for unlimited purposes, such as investigating stem cell therapies or treating cancer."

According to published literature, Tel Aviv University is one of the top five universities in the world pioneering the "lab on a chip" concept. The nanolabs can be used to evaluate several biological processes with practical applications, such as microbes in water, stem cells, or breast cancer development. Prof. Shacham-Diamand's active lab group publishes a major paper about once a month in this field, most recently in the journal Nano Letters.

Environmental, Medical and Defense Uses for "Mini-Labs"

Partnering with other Israeli scientists, Tel Aviv University is currently building and commercializing its water-testing mini-labs to measure and monitor how genetically engineered bacteria respond to pollution such as E. coli in water. Cities across Israel have expressed interest in the technology, as has the state of Hawaii.

But other uses are being explored as well. Funded by a $3 million grant from the United States Department of Defense Projects Agency (DARPA), the new lab-on-a-chip could become a defensive weapon that protects America from biological warfare. His system, Prof. Shacham-Diamand says, can be also modified to react to chemical threats and pollution. With some tweaking here and there, it can be updated as new threats are detected.

Prof. Shacham-Diamond's research has also attracted the interest of cancer researchers around the world. He recently addressed 400 physicians at a World Cancer Conference who are seeking new devices to measure and monitor cancer and pharmaceuticals. "They need sensors like Tel Aviv University's lab on a chip. It's a hot topic now," says Prof. Shacham-Diamond.

####

About American Friends of Tel Aviv University
American Friends of Tel Aviv University (www.aftau.org) supports Israel's leading and most comprehensive center of higher learning. In independent rankings, TAU's innovations and discoveries are cited more often by the global scientific community than all but 20 other universities worldwide.

Internationally recognized for the scope and groundbreaking nature of its research programs, Tel Aviv University consistently produces work with profound implications for the future.

For more information, please click here

Contacts:
George Hunka

212-742-9070

Copyright © American Friends of Tel Aviv University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Quantum states in a nano-object manipulated using a mechanical system August 3rd, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Announcements

Quantum states in a nano-object manipulated using a mechanical system August 3rd, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Homeland Security

Nanopaper as an optical sensing platform July 23rd, 2015

Iranian Scientists Design Nano Device to Detect Cyanogen Toxic Gas June 23rd, 2015

New sensing tech could help detect diseases, fraudulent art, chemical weapons June 1st, 2015

UCLA nanoscientists are first to model atomic structures of three bacterial nanomachines: Cryo electron microscope enables scientists to explore the frontiers of targeted antibiotics April 21st, 2015

Military

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Take a trip through the brain July 30th, 2015

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Reshaping the solar spectrum to turn light to electricity: UC Riverside researchers find a way to use the infrared region of the sun's spectrum to make solar cells more efficient July 27th, 2015

Environment

March 2016; 6th Int'l Conference on Nanostructures in Iran July 29th, 2015

Laboratorial Performance of Nanocomposite Membrane Improved in Water Purification July 28th, 2015

Nanosorbents Reduce Amount of Heavy Metals in Petrochemical Wastewater July 23rd, 2015

Nanopaper as an optical sensing platform July 23rd, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project