Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Tiny 'lab-on-a-chip' detects pollutants, disease and biological weapons

This is Yosi Shacham-Diamand of Tel Aviv University.

Credit: AFTAU
This is Yosi Shacham-Diamand of Tel Aviv University.
Credit: AFTAU

Abstract:
Tel Aviv University scientists develop highly accurate nano-scale biomonitoring solution

Tiny 'lab-on-a-chip' detects pollutants, disease and biological weapons

New York, NY and Tel Aviv, Israel | Posted on March 1st, 2009

For centuries, animals have been our first line of defense against toxins. A canary in a coalmine served as a living monitor for poisonous gases. Scientists used fish to test for contaminants in our water. Even with modern advances, though, it can take days to detect a fatal chemical or organism.

Until now. Working in the miniaturized world of nanotechnology, Tel Aviv University researchers have made an enormous -- and humane -- leap forward in the detection of pollutants.

A team led by Prof. Yosi Shacham-Diamand, vice-dean of TAU's Faculty of Engineering, has developed a nano-sized laboratory, complete with a microscopic workbench, to measure water quality in real time. Their "lab on a chip" is a breakthrough in the effort to keep water safe from pollution and bioterrorist threats, pairing biology with the cutting-edge capabilities of nanotechnology.

"We've developed a platform -- essentially a micro-sized, quarter-inch square 'lab' -- employing genetically engineered bacteria that light up when presented with a stressor in water," says Prof. Shacham-Diamand. Equipment on the little chip can work to help detect very tiny light levels produced by the bacteria.

Instead of using animals to help detect threats to a water supply, Prof. Shacham-Diamand says "Our system is based on a plastic chip that is more humane, much faster, more sensitive and much cheaper."

Tiny Lab-on-Chip Boosts Accuracy

"Basically, ours is an innovative advance in the 'lab on a chip' system," says Prof. Shacham-Diamand. "It's an ingenious nano-scale platform designed to get information out of biological events. Our solution can monitor water with never-before-achieved levels of accuracy. But as a platform, it can also be used for unlimited purposes, such as investigating stem cell therapies or treating cancer."

According to published literature, Tel Aviv University is one of the top five universities in the world pioneering the "lab on a chip" concept. The nanolabs can be used to evaluate several biological processes with practical applications, such as microbes in water, stem cells, or breast cancer development. Prof. Shacham-Diamand's active lab group publishes a major paper about once a month in this field, most recently in the journal Nano Letters.

Environmental, Medical and Defense Uses for "Mini-Labs"

Partnering with other Israeli scientists, Tel Aviv University is currently building and commercializing its water-testing mini-labs to measure and monitor how genetically engineered bacteria respond to pollution such as E. coli in water. Cities across Israel have expressed interest in the technology, as has the state of Hawaii.

But other uses are being explored as well. Funded by a $3 million grant from the United States Department of Defense Projects Agency (DARPA), the new lab-on-a-chip could become a defensive weapon that protects America from biological warfare. His system, Prof. Shacham-Diamand says, can be also modified to react to chemical threats and pollution. With some tweaking here and there, it can be updated as new threats are detected.

Prof. Shacham-Diamond's research has also attracted the interest of cancer researchers around the world. He recently addressed 400 physicians at a World Cancer Conference who are seeking new devices to measure and monitor cancer and pharmaceuticals. "They need sensors like Tel Aviv University's lab on a chip. It's a hot topic now," says Prof. Shacham-Diamond.

####

About American Friends of Tel Aviv University
American Friends of Tel Aviv University (www.aftau.org) supports Israel's leading and most comprehensive center of higher learning. In independent rankings, TAU's innovations and discoveries are cited more often by the global scientific community than all but 20 other universities worldwide.

Internationally recognized for the scope and groundbreaking nature of its research programs, Tel Aviv University consistently produces work with profound implications for the future.

For more information, please click here

Contacts:
George Hunka

212-742-9070

Copyright © American Friends of Tel Aviv University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Keeping electric car design on the right road: A closer look at the life-cycle impacts of lithium-ion batteries and proton exchange membrane fuel cells December 9th, 2016

Further improvement of qubit lifetime for quantum computers: New technique removes quasiparticles from superconducting quantum circuits December 9th, 2016

Chemical trickery corrals 'hyperactive' metal-oxide cluster December 8th, 2016

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D: Up-close, real-time, chemical-sensitive 3-D imaging offers clues for reducing cost/improving performance of catalysts for fuel-cell-powered vehicles and other applications December 8th, 2016

Announcements

Keeping electric car design on the right road: A closer look at the life-cycle impacts of lithium-ion batteries and proton exchange membrane fuel cells December 9th, 2016

Further improvement of qubit lifetime for quantum computers: New technique removes quasiparticles from superconducting quantum circuits December 9th, 2016

Researchers peer into atom-sized tunnels in hunt for better battery: May improve lithium ion for larger devices, like cars December 8th, 2016

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D: Up-close, real-time, chemical-sensitive 3-D imaging offers clues for reducing cost/improving performance of catalysts for fuel-cell-powered vehicles and other applications December 8th, 2016

Homeland Security

Nanosensors on the alert for terrorist threats: Scientists interested in the prospects of gas sensors based on binary metal oxide nanocomposites November 5th, 2016

Nanobionic spinach plants can detect explosives: After sensing dangerous chemicals, the carbon-nanotube-enhanced plants send an alert November 2nd, 2016

Notre Dame researchers find transition point in semiconductor nanomaterials September 6th, 2016

Down to the wire: ONR researchers and new bacteria August 18th, 2016

Military

Exotic insulator may hold clue to key mystery of modern physics: Johns Hopkins-led research shows material living between classical and quantum worlds December 8th, 2016

ANU invention to inspire new night-vision specs December 7th, 2016

Infrared instrumentation leader secures exclusive use of Vantablack coating December 5th, 2016

Quantum obstacle course changes material from superconductor to insulator December 1st, 2016

Environment

Keeping electric car design on the right road: A closer look at the life-cycle impacts of lithium-ion batteries and proton exchange membrane fuel cells December 9th, 2016

Semiconductor-free microelectronics are now possible, thanks to metamaterials November 9th, 2016

First time physicists observed and quantified tiny nanoparticle crossing lipid membrane November 7th, 2016

Nanosensors on the alert for terrorist threats: Scientists interested in the prospects of gas sensors based on binary metal oxide nanocomposites November 5th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project