Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > Highly sensitive dopamine detector uses 2D materials

Schematic of a highly selective dopamine detector using two-dimensional material.

CREDIT
Derrick Butler, Penn State
Schematic of a highly selective dopamine detector using two-dimensional material. CREDIT Derrick Butler, Penn State

Abstract:
A supersensitive dopamine detector can help in the early diagnosis of several disorders that result in too much or too little dopamine, according to a group led by Penn State and including Rensselaer Polytechnic Institute and universities in China and Japan.

Highly sensitive dopamine detector uses 2D materials

University Park, PA | Posted on August 7th, 2020

Dopamine is an important neurotransmitter that can be used to diagnose disorders such as Parkinson's disease, Alzheimer's disease and schizophrenia.

"If you can develop a very sensitive, yet simple-to-use and portable, detector that can identify a wide range of dopamine concentration, for instance in sweat, that could help in non-invasive monitoring of an individual's health," said Aida Ebrahimi, assistant professor of electrical engineering, Penn State, and a corresponding author on a paper published Aug. 7 in Science Advances.

Their work shows that by adding a small amount of manganese to a two-dimensional layered material called molybdenum disulfide, they can improve the sensitivity by many orders of magnitude compared to other reported results, while also achieving high specificity. Importantly, their detector is low-cost and flexible, and can detect dopamine in background media including buffer, serum and sweat, and in real-time.

"Regarding our method, electrochemical deposition is a new way of depositing these chemicals that is very simple and scalable," said Mauricio Terrones, Verne M. Willaman Professor of Physics, Materials Science and Chemistry and the second corresponding author. "The air force is interested in these neurotransmitters that are makers of stress. I envision this as a wearable sensor."

Humberto Terrones and his group, at RPI, performed the computational investigation that allowed them to explain how addition of manganese results in an improved response to dopamine. The experimental work was performed within the Center for Atomically Thin Multifunctional Coatings (ATOMIC) at Penn State.

"Combining the experimental results with computational studies proved to be very insightful, and I think we all learned much more throughout this project because of that," said Derrick Butler, a co-lead author on the paper and doctoral student at Penn State. "Developing these materials and applying them in a way that could improve the health and well-being of others makes the work especially enjoyable and rewarding."

His co-lead author, doctoral candidate Yu Lei, added, "One challenge is to develop a scalable method to bridge fundamental studies and practical applications. Our method is based on electrodeposition, which has been widely used in industry, thus providing a scalable route to functionalize MoS2 in a scalable way. Also, I believe this multidisciplinary team is the key to find the right way to functionalize MoS2 for ultrasensitive dopamine detection."

In further work, the group hopes to find other material combinations to detect a variety of other biomarkers with the specificity of their current sensor. Creating such a "toolkit" combining experimental investigations with computational methods will lead to new materials with multifunctional capabilities. This might be useful beyond human health, for example, for detecting noxious gases, water contamination or biodefense agents.

"In future, we can envision a combined sensor/actuator that can detect the dopamine and provide therapy at the same time. The sensors can be integrated with miniaturized chips for integration of sensing, actuating, control and data processing," Ebrahimi said.

###

In addition to Ebrahimi, Lei, Butler and the Terrones brothers, authors include Fu Zhang and Tomotaroh Granzier-Nakajiwa, former or current doctoral students at Penn State, and Kazinora Fujisawa, currently a post-doctoral scholar, Penn State. Their paper is titled "Single-Atom Doping of MoS2 with Manganese Enables Ultrasensitive Detection of Dopamine: Experimental and Computational Approach."

National Science Foundation, IUCRC-ATOMIC Center and Ebrahimi's Start-up fund provided support for this project.

####

For more information, please click here

Contacts:
A'ndrea Elyse Messer

814-865-5689

@penn_state

Terrones can be contacted at
Ebrahimi can be contacted at

Copyright © Penn State

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New technology helps reveal inner workings of human genome June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

2 Dimensional Materials

Controlled synthesis of crystal flakes paves path for advanced future electronics June 17th, 2022

Solving the puzzle of 2D disorder: An interdisciplinary team developed a new method to characterize disorder in 2D materials June 17th, 2022

UBCO researchers change the game when it comes to activity tracking: Flexible, highly sensitive motion device created by extrusion printing June 17th, 2022

Bumps could smooth quantum investigations: Rice University models show unique properties of 2D materials stressed by contoured substrates June 10th, 2022

UCI scientists turn a hydrogen molecule into a quantum sensor: New technique enables precise measurement of electrostatic properties of materials April 22nd, 2022

Wearable electronics

‘Fruitcake’ structure observed in organic polymers June 3rd, 2022

Graphene crystals grow better under copper cover April 1st, 2022

A molecule like a nanobattery: Chemical scientists decipher complex electronic structure of a three-nuclear metallorganic compound with the capacity of donating and receiving multiple electrons June 9th, 2021

Govt.-Legislation/Regulation/Funding/Policy

Solving the solar energy storage problem with rechargeable batteries that can convert and store energy at once June 24th, 2022

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

UBCO researchers change the game when it comes to activity tracking: Flexible, highly sensitive motion device created by extrusion printing June 17th, 2022

University of Illinois Chicago joins Brookhaven Lab's Quantum Center June 10th, 2022

Possible Futures

New technology helps reveal inner workings of human genome June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

Sensors

Photonic integrated erbium doped amplifiers reach commercial performance: Boosting light power revolutionizes communications and autopilots June 17th, 2022

A one-stop shop for quantum sensing materials May 27th, 2022

Going gentle on mechanical quantum systems: New experimental work establishes how quantum properties of mechanical quantum systems can be measured without destroying the quantum state May 13th, 2022

New nanomechanical oscillators with record-low loss May 13th, 2022

Discoveries

New technology helps reveal inner workings of human genome June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

Announcements

New technology helps reveal inner workings of human genome June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters

Quantum network nodes with warm atoms June 24th, 2022

New technology helps reveal inner workings of human genome June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Homeland Security

Sensors developed at URI can identify threats at the molecular level: More sensitive than a dog's nose and the sensors don't get tired May 21st, 2021

UCF researchers generate attosecond light from industrial laser: The ultrafast measurement of the motion of electrons inside atoms, molecules and solids at their natural time scale is known as attosecond science and could have important implications in power generation, chemical- August 25th, 2020

RIT researchers build micro-device to detect bacteria, viruses: New process improves lab-on-chip devices to isolate drug-resistant strains of bacterial infection, viruses April 17th, 2020

Nanomaterial fabric destroys nerve agents in battlefield-relevant conditions: Metal-organic framework-based composites don’t need liquid water to work January 14th, 2020

Military

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

Bumps could smooth quantum investigations: Rice University models show unique properties of 2D materials stressed by contoured substrates June 10th, 2022

Nanostructured fibers can impersonate human muscles June 3rd, 2022

Lightening up the nanoscale long-wavelength optoelectronics May 13th, 2022

Environment

University of Strathclyde and National University of Singapore to co-ordinate satellite quantum communications May 13th, 2022

Lightening up the nanoscale long-wavelength optoelectronics May 13th, 2022

Water processing: light helps degrade hormones: KIT researchers use polymer membranes coated with titanium dioxide for photocatalytic cleaning – results are reported in Nature Nanotechnology April 22nd, 2022

National Cheng Kung University researchers present new solution for wastewater remediation: The new eco-friendly nanocomposite hydrogels can be reused many times to adsorb ionic pollutants from wastewater April 15th, 2022

Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records

Solving the solar energy storage problem with rechargeable batteries that can convert and store energy at once June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Advances in lithium niobate photonics: High performance integrated LN-based photonic devices have developed rapidly in recent years, and many different structures have been demonstrated for various application scenarios—are we about to enter a new era of LN photonics? June 24th, 2022

Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project