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September 24th, 2008

Nanoparticles stick around for longer

Abstract:
Philips Research of the Netherlands is teaming up with the University of Urbino in Italy to develop contrast agents for medical imaging applications. The research alliance will study the encapsulation of magnetic-nanoparticle-based agents inside living blood cells, with a view to prolonging their retention time in blood.

Nanoparticle-based contrast agents show considerable promise for use in diagnostic imaging. However, when injected as free particles, they are quickly excreted from the blood via the patient's liver, limiting their usefulness. By capturing the magnetic nanoparticles inside the patient's own red blood cells, they remain protected from the body's excretion mechanisms for much longer periods - possibly as long as 120 days, the typical lifetime of a healthy red blood cell.

Source:
medicalphysicsweb.org

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