Home > Press > Effective Nano-Micelles Designed in Iran to Treat Cancer
Abstract:
Iranian researchers designed highly effective nano-micelles to carry anticancer drugs into the tumor tissues.
The nano-micelles were produced from commercial raw materials through a relatively simple and cost-effective method.
Cisplatin is one of the most common drugs in cancer treatment. The drug is used in the treatment of advanced testicular cancer, advanced ovarian cancer, bladder, head, neck and lungs cancers. However, there are some problems in the application of cisplatin and its derivatives (like oxaliplatin and carboplatin), including very low solubility at biological media, large side effects and non-selective performance when they deal with normal and cancerous cells. The aim of the research was to overcome the problems by using smart nano drug delivery systems.
In this research, a relatively simple synthetic method was used to produce polymeric micelle by application of raw materials that are all commercially available.
The design of the new nanodrug prevents very much the harmful effects of the drug on healthy tissues of the body. In addition, cancer cell exclusive guiding ligand, which is folic acid, has been used on the surface of the nanodrug so that the produced nanodrug can accumulate in the tumor tissue and in cancerous cells as fast as possible.
Very promising results have been obtained for these multi-functional nano-micelles, and it is predicted that the nanodrug can be produced after carrying out further in-vivo studies at various phases. Therefore, the use of new generation of carriers in chemotherapy decreases side effects of anticancer drugs while it increases their effectiveness.
Results of the research have been published in Polymer Chemistry, vol. 6, issue 15, 2015, pp. 1-9.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related News Press |
News and information
Researchers develop artificial building blocks of life March 8th, 2024
Cancer
Super-efficient laser light-induced detection of cancer cell-derived nanoparticles: Skipping ultracentrifugation, detection time reduced from hours to minutes! October 6th, 2023
The medicine of the future could be artificial life forms October 6th, 2023
Nanomedicine
High-tech 'paint' could spare patients repeated surgeries March 8th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Discoveries
What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024
Researchers’ approach may protect quantum computers from attacks March 8th, 2024
High-tech 'paint' could spare patients repeated surgeries March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Announcements
What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Researchers develop artificial building blocks of life March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
The latest news from around the world, FREE | ||
Premium Products | ||
Only the news you want to read!
Learn More |
||
Full-service, expert consulting
Learn More |
||