Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > On the frontiers of cyborg science

Abstract:
Title

Nanoelectronics meets biology: From new tools to electronic therapeutics

Abstract

Nanoscale materials enable unique opportunities at the interface between the physical and life sciences, and the interfaces between nanoelectronic devices and cells, cell networks, and tissue makes possible communication between these systems at the length scale relevant to biological function. In this presentation, the development of nanowire nanoelectronic devices and their application as powerful tools for the recording and stimulation from the level of single cells to tissue will be discussed. First, a brief introduction to nanowire nanoelectronic devices as well as comparisons to other tools will be presented to illuminate the unique strengths and opportunities enabled by active electronic devices. Second, opportunities for the creation of powerful new probes capable of intracellular recording and stimulation at scales heretofore not possible with existing electrophysiology techniques will be discussed. Third, we will take an 'out-of-the-box' look and consider merging nanoelectronics with cell networks in three-dimensions (3D). We will introduce general methods and provide examples of synthetic 'cyborg' tissues innervated with nanoelectronic sensor elements that enabling recording and modulating activity in 3D for these engineered tissues. In addition, we will discuss extension of these nanoelectronic scaffold concepts for the development of revolutionary probes for acute and chronic brain mapping as well as their potential as future electronic therapeutics. The prospects for broad-ranging applications in the life sciences as the distinction between electronic and living systems is blurred in the future will be discussed.

Selected References

1. B. Tian et al., Nature Mater. 11, 986-994 (2012)

2. X. Duan et al., Nano Today 8, 351-373 (2013)

3. Q. Qing et al., Nature Nanotechnol. 9, 142-147 (2014)

On the frontiers of cyborg science

San Francisco, CA | Posted on August 10th, 2014

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits. Now taking this human-machine concept to an unprecedented level, pioneering scientists are working on the seamless marriage between electronics and brain signaling with the potential to transform our understanding of how the brain works — and how to treat its most devastating diseases.

Their presentation is taking place at the 248th National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society. The meeting features nearly 12,000 presentations on a wide range of science topics and is being held here through Thursday.

"By focusing on the nanoelectronic connections between cells, we can do things no one has done before," says Charles M. Lieber, Ph.D. "We're really going into a new size regime for not only the device that records or stimulates cellular activity, but also for the whole circuit. We can make it really look and behave like smart, soft biological material, and integrate it with cells and cellular networks at the whole-tissue level. This could get around a lot of serious health problems in neurodegenerative diseases in the future."

These disorders, such as Parkinson's, that involve malfunctioning nerve cells can lead to difficulty with the most mundane and essential movements that most of us take for granted: walking, talking, eating and swallowing.

Scientists are working furiously to get to the bottom of neurological disorders. But they involve the body's most complex organ — the brain — which is largely inaccessible to detailed, real-time scrutiny. This inability to see what's happening in the body's command center hinders the development of effective treatments for diseases that stem from it.

By using nanoelectronics, it could become possible for scientists to peer for the first time inside cells, see what's going wrong in real time and ideally set them on a functional path again.

For the past several years, Lieber has been working to dramatically shrink cyborg science to a level that's thousands of times smaller and more flexible than other bioelectronic research efforts. His team has made ultrathin nanowires that can monitor and influence what goes on inside cells. Using these wires, they have built ultraflexible, 3-D mesh scaffolding with hundreds of addressable electronic units, and they have grown living tissue on it. They have also developed the tiniest electronic probe ever that can record even the fastest signaling between cells.

Rapid-fire cell signaling controls all of the body's movements, including breathing and swallowing, which are affected in some neurodegenerative diseases. And it's at this level where the promise of Lieber's most recent work enters the picture.

In one of the lab's latest directions, Lieber's team is figuring out how to inject their tiny, ultraflexible electronics into the brain and allow them to become fully integrated with the existing biological web of neurons. They're currently in the early stages of the project and are working with rat models.

"It's hard to say where this work will take us," he says. "But in the end, I believe our unique approach will take us on a path to do something really revolutionary."

###

Lieber acknowledges funding from the U.S. Department of Defense, the National Institutes of Health and the U.S. Air Force.

####

About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 161,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

For more information, please click here

Contacts:
Michael Bernstein
415-978-3506 (S.F. Press Center, Aug. 9-13)
202-872-6042


Katie Cottingham, Ph.D.
415-978-3506 (S.F. Press Center, Aug. 9-13)
301-775-8455

Copyright © American Chemical Society

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

Brain-Computer Interfaces

Nano memory cell can mimic the brain’s long-term memory May 14th, 2015

Carbon nanotube fibers make superior links to brain: Rice University invention provides two-way communication with neurons March 25th, 2015

IBM Announces $3 Billion Research Initiative to Tackle Chip Grand Challenges for Cloud and Big Data Systems: Scientists and engineers to push limits of silicon technology to 7 nanometers and below and create post-silicon future July 10th, 2014

Noninvasive brain control: New light-sensitive protein enables simpler, more powerful optogenetics June 30th, 2014

Govt.-Legislation/Regulation/Funding/Policy

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Physicists precisely measure interaction between atoms and carbon surfaces May 28th, 2015

Linking superconductivity and structure May 28th, 2015

Chemists discover key reaction mechanism behind the highly touted sodium-oxygen battery May 28th, 2015

Nanomedicine

New chip makes testing for antibiotic-resistant bacteria faster, easier: Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time May 28th, 2015

Arrowhead to Present at Jefferies 2015 Healthcare Conference May 27th, 2015

Seeing the action: UCSB researchers develop a novel device to image the minute forces and actions involved in cell membrane hemifusion May 27th, 2015

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015

Announcements

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Global Carbon Nanotubes (CNT) Market Expected To Reach USD 3.42 Billion By 2022 May 29th, 2015

Military

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Linking superconductivity and structure May 28th, 2015

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

New Antibacterial Wound Dressing in Iran Can Display Replacement Time May 22nd, 2015

Events/Classes

SouthWest NanoTechnologies Introduces AgeNT™ Transparent Conductor System at SID Display Week, Booth #543 May 28th, 2015

Technology for Tomorrow’s Market Opportunities and Challenges: LetiDays Grenoble Presents the Possibilities: June 24-25 Event Includes Focus on IoT-Augmented Mobility and Leti’s Latest Results on Silicon Technologies, Sensors, Health Applications and Smart Cities May 27th, 2015

Arrowhead to Present at Jefferies 2015 Healthcare Conference May 27th, 2015

Haydale Named Lead Sponsor for Cambridge Graphene Festival May 22nd, 2015

Alliances/Partnerships/Distributorships

Samtec, Global Provider of Interconnect Systems, Joins IRT Nanoelec Silicon Photonics Program May 21st, 2015

SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium: May 20th, 2015

Industrial Nanotech, Inc. Announces Official Launch of the Eagle Platinum Tile™ May 19th, 2015

DiATOME enables surface preparation for AFM and FIB May 19th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project