Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nano-paper filter removes viruses

The illustration shows the nanofibers in white and the virus in green.

Photograph: Björn Syse
The illustration shows the nanofibers in white and the virus in green.

Photograph: Björn Syse

Abstract:
Nanotechnology and Functional Materials, Uppsala University have developed a paper filter, which can remove virus particles with the efficiency matching that of the best industrial virus filters. The paper filter consists of 100 percent high purity cellulose nanofibers, directly derived from nature.

Nano-paper filter removes viruses

Uppsala, Sweden | Posted on March 31st, 2014

The research was carried out in collaboration with virologists from the Swedish University of Agricultural Sciences/Swedish National Veterinary Institute and is published in the Advanced Healthcare Materials journal.

Virus particles are very peculiar objects- tiny (about thousand times thinner than a human hair) yet mighty. Viruses can only replicate in living cells but once the cells become infected the viruses can turn out to be extremely pathogenic. Viruses can actively cause diseases on their own or even transform healthy cells to malignant tumors.

"Viral contamination of biotechnological products is a serious challenge for production of therapeutic proteins and vaccines. Because of the small size, virus removal is a non-trivial task, and, therefore, inexpensive and robust virus removal filters are highly demanded" says Albert Mihranyan, Associate Professor at the Division of Nanotechnology and Functional Materials, Uppsala University, who heads the study.

Cellulose is one of the most common materials to produce various types of filters because it is inexpensive, disposable, inert and non-toxic. It is also mechanically strong, hydrophyllic, stable in a wide range of pH, and can withstand sterilization e.g. by autoclaving. Normal filter paper, used for chemistry, has too large pores to remove viruses.

The undergraduate student Linus Wågberg, Professor Maria Strømme, and Associate Professor Albert Mihranyan at the Division of Nanotechnology and Functional Materials, Uppsala University, in collaboration with virologists Dr. Giorgi Metreveli, Eva Emmoth, and Professor Sándor Belák from the Swedish University of Agricultural Sciences (SLU)/Swedish National Veterinary Institute (SVA), report a design of a paper filter which is capable of removing virus particles with the efficiency matching that of the best industrial virus filters. The reported paper filter, which is manufactured according to the traditional paper making processes, consists of 100 percent high purity cellulose nanofibers directly derived from nature.

The discovery is a result of a decade long research on the properties of high surface area nanocellulose materials, which eventually enabled the scientists to tailor the pore size distribution of their paper precisely in the range desirable for virus filtration.

Previously described virus removal paper filters relied heavily on interception of viruses via electrostatic interactions, which are sensitive to pH and salt concentrations, whereas the virus removal filters made from synthetic polymers and which rely on size-exclusion are produced through tedious multistep phase-inversion processing involving hazardous solvents and rigorous pore annealing processing.

Incidentally, it was the Swedish chemist J.J. Berzelius (1779-1848), one of the most famous alumni of Uppsala University, who was the first one to use the pure wet-laid-all-rag paper for separation of precipitates in chemical analysis. In a way, the virus removal nano-paper filter developed by the Uppsala scientists is the modern day analogue of the widely popular Swedish Filter Paper developed by Berzelius nearly two centuries ago.

####

For more information, please click here

Contacts:
Albert Mihranyan

46-701-679-037

Copyright © Uppsala University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

The article is published in the Advanced Healthcare Materials journal on March 31, 2014:

Related News Press

News and information

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

JPK reports on the use of AFM and the CellHesion module to study plant cells at the University of Queensland November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Nanomedicine

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research reveals how our bodies keep unwelcome visitors out of cell nuclei November 24th, 2014

ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality November 24th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Discoveries

Lawrence Livermore researchers develop efficient method to produce nanoporous metals November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Blu-ray disc can be used to improve solar cell performance: Data storage pattern transferred to solar cell increases light absorption November 25th, 2014

Materials/Metamaterials

Lawrence Livermore researchers develop efficient method to produce nanoporous metals November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Aromatic food chemistry to the making of copper nanowires November 24th, 2014

Novel Method Found for Connection of Metallic Alloys to Polymers November 23rd, 2014

Announcements

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

JPK reports on the use of AFM and the CellHesion module to study plant cells at the University of Queensland November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Lawrence Livermore researchers develop efficient method to produce nanoporous metals November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Blu-ray disc can be used to improve solar cell performance: Data storage pattern transferred to solar cell increases light absorption November 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE