Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Bruker Introduces High-Performance Opterra™ Multipoint Scanning Confocal Microscope: Opterra Offers Superior Integration of Confocal Microscopy and Photoactivation for Biology Applications

Abstract:
Today at the 2013 American Society for Cell Biology Annual Meeting, Bruker introduced the Opterra Multipoint Scanning Confocal Microscope, which sets a new standard for integration of confocal imaging with photoactivation. The new Opterra microscope utilizes a number of innovative features to obtain the speed of wide-field imaging and the resolution of traditional confocal systems while minimizing phototoxicity, making it an ideal solution for gentle and fast confocal imaging of live cell preparations. A seven-position pinhole/slit aperture allows the Opterra to be optimized for varying objective lens magnifications that results in the ability to image deeper into tissue versus conventional disk scanning confocal microscopes.

Bruker Introduces High-Performance Opterra™ Multipoint Scanning Confocal Microscope: Opterra Offers Superior Integration of Confocal Microscopy and Photoactivation for Biology Applications

New Orleans, LA | Posted on December 16th, 2013

"The Opterra has proven to be a major advance in terms of rapid, time-based volumetric imaging," said Dr. Mario De Bono, Medical Research Council Group Leader at the Laboratory of Molecular Biology, Cambridge University, UK. "The speed of the system, coupled with its sensitivity and resolution has significantly enhanced our ability to visualize neural activity in 3D in C. elegans at speeds that were previously not possible. The ability to change pinhole size is great, as it allows us to match the imaging setup with the specimen."

"Our new Opterra provides a flexible optical workstation for cell biologists to perform confocal imaging of live cells and small organisms with simultaneous point and area scanning for photoactivation and photoablation," explained Mike Szulczewski, Vice President and General Manager of Bruker's Fluorescence Microscopy business. "The tight integration of optical imaging with optical stimulation techniques enables investigators to take full advantage of today's imaging and photochemical probe technologies."

About Opterra

The Opterra Multipoint Scanning Confocal Microscope is based on Bruker's patented swept-field imaging scanner. This scanner allows high-speed confocal imaging of live cell and small organism preparations at resolutions comparable to conventional point scanners, but with minimal phototoxicty. Opterra includes a second scanner for photo- activation/bleaching/ablation, which can operate simultaneously with imaging. The photoactivation scanner can be coupled to both visible and multiphoton lasers, thus allowing the use of the full range of photo-activatable molecules and photochemical techniques available to life science researchers. In the case of multiphoton lasers, this provides precise three-dimensional control over photoactivation. The applications addressed by Opterra include response to DNA damage, kinetics of photoactivatable fluorescent proteins, fluorescence recovery after photo-bleaching (FRAP), response to local stimulation of channel proteins, and response to cell membrane damage. Bruker's Prairie View 5.0 software provides an intuitive interface with a rich environment for defining image acquisition and photoactivation protocols.

####

About Bruker Corporation
Bruker Corporation is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis.

For more information, please click here

Contacts:
Stephen Hopkins, Marketing Communications
Bruker Nano Surfaces Division
3400 East Britannia Drive, Suite 150, Tucson, AZ 85706
T: +1 (520) 741-1044 x1022

Copyright © Bruker Corporation

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Nanomedicine

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Announcements

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Tools

Exploring phosphorene, a promising new material April 29th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Chemists use DNA to build the world's tiniest thermometer April 27th, 2016

Bruker Introduces Dimension FastScan Pro Industrial AFM: Providing Nanometer-Resolution at High Scan Rates for up to 300-mm Samples April 26th, 2016

Events/Classes

Researchers create a first frequency comb of time-bin entangled qubits: Discovery is a significant step toward multi-channel quantum communication and higher capacity quantum computers April 28th, 2016

Introducing the RE標ORK Bio-inspired Robotics Summit in Berlin April 27th, 2016

ORIG3N Added to Companies Presenting at Harris & Harris Group's Annual Meeting, Tuesday June 7, 2016, the New York Genome Center April 27th, 2016

Team builds first quantum cascade laser on silicon: Eliminates the need for an external light source for mid-infrared silicon photonic devices or photonic circuits April 21st, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic