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Home > Press > Making a common cosmetic and sunblock ingredient safer

Using a particular type of titanium dioxide in sunblock and cosmetics could reduce the potential health risks associated with the widely used compound.
Credit: Hemera/Thinkstock
Using a particular type of titanium dioxide in sunblock and cosmetics could reduce the potential health risks associated with the widely used compound.

Credit: Hemera/Thinkstock

Abstract:
Using a particular type of titanium dioxide — a common ingredient in cosmetics, food products, toothpaste and sunscreen — could reduce the potential health risks associated with the widely used compound. The report on the substance, produced by the millions of tons every year for the global market, appears in the ACS journal Chemical Research in Toxicology.

Making a common cosmetic and sunblock ingredient safer

Washington, DC | Posted on September 25th, 2013

Francesco Turci and colleagues explain that titanium dioxide (TiO2) is generally considered a safe ingredient in commercially available skin products because it doesn't penetrate healthy skin. But there's a catch. Research has shown that TiO2 can cause potentially toxic effects when exposed to ultraviolet light, which is in the sun's rays and is the same kind of light that the compound is supposed to offer protection against. To design a safer TiO2 for human use, the researchers set out to test different forms of the compound, each with its own architecture.

They tested titanium dioxide powders on pig skin (which often substitutes for human skin in these kinds of tests) with indoor lighting, which has very little ultraviolet light in it. They discovered that one of the two most commonly used crystalline forms of TiO2, called rutile, easily washes off and has little effect on skin. Anatase, the other commonly used form, however, was difficult to wash off and damaged the outermost layer of skin — even in low ultraviolet light. It appears to do so via "free radicals," which are associated with skin aging. "The present findings strongly encourage the use of the less reactive, negatively charged rutile to produce safer TiO2-based cosmetic and pharmaceutical products," the researchers conclude.

The authors acknowledge funding from Regione Piemonte.

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About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

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Contacts:
Michael Bernstein

202-872-6042

Francesco Turci, Ph.D.
University of Torino, Chemistry Department
“G. Scansetti” Interdepartmental Center and NIS Excellence Center
via P. Giuria 7
10125 Torino
Italy

Copyright © American Chemical Society

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DOWNLOAD FULL-TEXT ARTICLE - “Crystalline Phase Modulates the Potency of Nanometric TiO2 to Adhere and Perturb the Stratum Corneum of Porcine Skin under Indoor Light”

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