Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Breakthrough in sensing at the nanoscale

Abstract:
Researchers have made a breakthrough discovery in identifying the world's most sensitive nanoparticle and measuring it from a distance using light. These super-bright, photostable and background-free nanocrystals enable a new approach to highly advanced sensing technologies using optical fibres.

Breakthrough in sensing at the nanoscale

Adelaide, Australia | Posted on September 1st, 2013

This discovery, by a team of researchers from Macquarie University, the University of Adelaide, and Peking University, opens the way for rapid localisation and measurement of cells within a living environment at the nanoscale, such as the changes to a single living cell in the human body in response to chemical signals.

Published in Nature Nanotechnology today, the research outlines a new approach to advanced sensing that has been facilitated by bringing together a specific form of nanocrystal, or "SuperDot™" with a special kind of optical fibre that enables light to interact with tiny (nanoscale) volumes of liquid.

"Up until now, measuring a single nanoparticle would have required placing it inside a very bulky and expensive microscope," says Professor Tanya Monro, Director of the University of Adelaide's Institute for Photonics and Advanced Sensing (IPAS) and ARC Australian Laureate Fellow. "For the first time, we've been able to detect a single nanoparticle at one end of an optical fibre from the other end. That opens up all sorts of possibilities in sensing."

"Using optical fibres we can get to many places such as inside the living human brain, next to a developing embryo, or within an artery ‒ locations that are inaccessible to conventional measurement tools.

"This advance ultimately paves the way to breakthroughs in medical treatment. For example, measuring a cell's reaction in real time to a cancer drug means doctors could tell at the time treatment is being delivered whether or not a person is responding to the therapy."

The performance of sensing at single molecular level had previously been limited by both insufficient signal strength and interference from background noise. The special optical fibre engineered at IPAS also proved useful in understanding the properties of nanoparticles. "Material scientists have faced a huge challenge in increasing the brightness of nanocrystals," says Dr. Jin, ARC Fellow at Macquarie University's Advanced Cytometry Laboratories. "Using these optical fibres, however, we have been given unprecedented insight into the light emissions. Now, thousands of emitters can be incorporated into a single SuperDot™ - creating a far brighter, and more easily detectable nanocrystal."

Under infrared illumination, these SuperDots™ selectively produce bright blue, red and infrared light, with a staggering thousand times more sensitivity than existing materials. "Neither the glass of the optical fibre nor other background biological molecules respond to infrared, so that removed the background signal issue. By exciting these SuperDots™ we were able to lower the detection limit to the ultimate level - a single nanoparticle," says Jin.

"The trans-disciplinary research from multiple institutions has paved the way for this innovative discovery," says Jin, "with the interface of experts in nanomaterials, photonics engineering, and biomolecular frontiers."

"These joint efforts will ultimately benefit patients around the world - for example, our industry partners Minomic International Ltd and Patrys Ltd are developing uses for SuperDots™ in cancer diagnostic kits, detecting incredibly low numbers of biomarkers within conditions like prostate and multiple myeloma cancer." Macquarie is now actively seeking other industrial partners with the capacity to jointly develop solutions outside of these fields.

####

For more information, please click here

Contacts:
Dr Dayong Jin (email)
Senior Lecturer, Advanced
Cytometry Laboratories
Macquarie University
Business: +61 9850 4168
Mobile: +61 433 875 470

Professor Tanya Monro (email)
website
Director, Institute for Photonics & Advanced Sensing
School of Chemistry and Physics
The University of Adelaide
Business: +61 8 8303 3955
Mobile: 0400 649 369

Ms Robyn Mills (email)
Media and Communications Officer
The University of Adelaide
Business: +61 8 8313 6341
Mobile: +61 410 689 084

For queries about the SuperDotTM technology:
Joanna Wheatley (email)
Media Manager
Macquarie University
Business: +61 2 9850 1039

Copyright © University of Adelaide

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Feynman Prize Winners Announced! April 26th, 2015

New ASTM Standards Will Help Educate Present and Future Nanotechnology Workforces April 26th, 2015

Heat makes electrons’ spin in magnetic superconductors April 26th, 2015

QD Vision Wins 2015 Bronze Edison Award for Color IQ™ Quantum Dot Technology April 26th, 2015

Nanomedicine

Northwestern scientists develop first liquid nanolaser: Technology could lead to new way of doing 'lab on a chip' medical diagnostics April 25th, 2015

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

A silver lining: UCSB researchers cradle silver nanoclusters inside synthetic DNA to create a programmed, tunable fluorescent array April 23rd, 2015

Sensors

ORNL reports method that takes quantum sensing to new level April 23rd, 2015

New class of 3D-printed aerogels improve energy storage April 22nd, 2015

‘Oxford Instruments Young Nanoscientist India Award 2015’ to Prof. Arindam Ghosh April 20th, 2015

Optical resonance-based biosensors designed for medical applications April 18th, 2015

Discoveries

Heat makes electrons’ spin in magnetic superconductors April 26th, 2015

SEFCU, SUNY Poly CNSE Announce Winning Student-Led Teams in the 6th Annual $500,000 New York Business Plan Competition April 25th, 2015

Northwestern scientists develop first liquid nanolaser: Technology could lead to new way of doing 'lab on a chip' medical diagnostics April 25th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Materials/Metamaterials

Electron spin brings order to high entropy alloys April 23rd, 2015

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

Surface matters: Huge reduction of heat conduction observed in flat silicon channels April 23rd, 2015

Nanoparticles Used to Improve Mechanical, Thermal Properties of Cellulose Fibers April 23rd, 2015

Announcements

Feynman Prize Winners Announced! April 26th, 2015

New ASTM Standards Will Help Educate Present and Future Nanotechnology Workforces April 26th, 2015

Heat makes electrons’ spin in magnetic superconductors April 26th, 2015

QD Vision Wins 2015 Bronze Edison Award for Color IQ™ Quantum Dot Technology April 26th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Heat makes electrons’ spin in magnetic superconductors April 26th, 2015

Northwestern scientists develop first liquid nanolaser: Technology could lead to new way of doing 'lab on a chip' medical diagnostics April 25th, 2015

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Photonics/Optics/Lasers

Northwestern scientists develop first liquid nanolaser: Technology could lead to new way of doing 'lab on a chip' medical diagnostics April 25th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

ORNL reports method that takes quantum sensing to new level April 23rd, 2015

Quantum 'paparazzi' film photons in the act of pairing up April 22nd, 2015

Research partnerships

Heat makes electrons’ spin in magnetic superconductors April 26th, 2015

Pseudoparticles travel through photoactive material: KIT scientists measure important process in the conversion of light energy -- publication in Nature Communications April 24th, 2015

Electron spin brings order to high entropy alloys April 23rd, 2015

Surface matters: Huge reduction of heat conduction observed in flat silicon channels April 23rd, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project