Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > JPK reports on the research activities of the Nanophysics Group at the Istituto Italiano di Tecnologia based in Genova

Dr Claudio Canale, Professor Alberto Diaspro, Jenu Chacko-Varghese and Dr Benjamin Harke - the group to have coupled STED and AFM at the Department of Nanophyiscs, IIT, Genova.
Dr Claudio Canale, Professor Alberto Diaspro, Jenu Chacko-Varghese and Dr Benjamin Harke - the group to have coupled STED and AFM at the Department of Nanophyiscs, IIT, Genova.

Abstract:
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the research studies of the nanophysics group to couple the chemical information of STED microscopy with the high resolution spatial and force measurements provided by AFM to study biological samples in liquid.

JPK reports on the research activities of the Nanophysics Group at the Istituto Italiano di Tecnologia based in Genova

Berlin, Germany | Posted on April 16th, 2013

The Istituto Italiano di Tecnologia (IIT) was founded in 2003 in the city of Genova to promote Italy's technological development and advanced education. Professor Alberto Diaspro is the Director of the Department of Nanophysics. His research includes the design, realization and utilization of optical and biophysical instrumentation such as far-field super resolution optical microscopy and nanoscopy, conventional and confocal microscopy, two-photon fluorescence microscopy and spectroscopy architecture, and scanning probe microscopy (STM, SNOM, AFM). This last area has led to collaborations with JPK Instruments.

Dr Claudio Canale is a team leader in the group focusing on the application of scanning probe techniques in the study of bio-materials and bio-mechanisms. One of his main projects has been to couple STED (stimulated emission depletion microscopy) and atomic force microscopy (AFM). Describing this work, Dr Canale said "in our department, an entire group works on the development of optical super-resolution techniques and this has led to a STED microscope based on a conventional multi-photon platform from Nikon Instruments. Together with Dr Benjamin Harke, we had the idea to couple the capability of this instrument with those offered by an AFM. For the AFM, we chose the NanoWizard® from JPK."

There have been several iterations of the new combined set-up. This work has been reported in a paper published by the group in the journal, Optical Nanoscopy1. Now, the main goal is to characterize biological processes having simultaneous access to morphological and mechanical properties and coupling both of them with chemical recognition capability directly provided by STED with a resolution in the order of tens of nanometers. Working on model membranes, Dr Canale says "we can recognize target molecules or particular membrane components by STED and we can look at the fine structural and mechanical changes by AFM."

The choice of JPK's AFM came after experience using many different commercial AFM systems. Settling on the NanoWizard, Dr Canale comments "I found the JPK system extraordinarily comfortable for this application. I think that JPK have produced a system with a special aptitude towards biology. This approach to the development of stable systems that provide state of the art performance applications in liquid with a user-friendly approach that makes the system easily accessible not only to users with a physical background but also to biologists and biochemists. In particular, I have been impressed by the unique capability of this instrument to work in a liquid environment with both nanometric spatial and piconewton force resolution."

For more details about JPK's specialist products and applications for the bio and nano sciences, please contact JPK on +49 30533112070, visit the web site: www.jpk.com or see more on Facebook: www.jpk.com/facebook and YouTube: www.youtube.com/jpkinstruments.

Reference: 1) Harke et al., Optical Nanoscopy 1:3 (2012)

####

About JPK Instruments (JPK)
JPK Instruments AG is a world-leading manufacturer of nanoanalytic instruments - particularly atomic force microscope (AFM) systems and optical tweezers - for a broad range of applications reaching from soft matter physics to nano-optics, from surface chemistry to cell and molecular biology. From its earliest days applying atomic force microscope (AFM) technology, JPK has recognized the opportunities provided by nanotechnology for transforming life sciences and soft matter research. This focus has driven JPK's success in uniting the worlds of nanotechnology tools and life science applications by offering cutting-edge technology and unique applications expertise. Headquartered in Berlin and with direct operations in Dresden, Cambridge (UK),

Singapore, Tokyo and Paris (France), JPK maintains a global network of distributors and support centers and provides on the spot applications and service support to an ever-growing community of researchers.

For more information, please click here

Contacts:
JPK Instruments AG
Bouchéstrasse 12
Haus 2, Aufgang C
Berlin 12435
Germany
T +49 30533112070
F +49 30 5331 22555
www.jpk.com



Bouchéstrasse 12
Haus 2, Aufgang C
Berlin 12435
Germany
T +49 30533112070
F +49 30 5331 22555
www.jpk.com
Talking Science Limited
39 de Bohun Court
Saffron Walden
Essex CB10 2BA
United Kingdom
T +44(0)1799 521881
M +44(0)7843 012997
www.talking-science.com

Copyright © JPK Instruments (JPK)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Hybrid nanoantennas -- next-generation platform for ultradense data recording April 28th, 2016

Superfast light source made from artificial atom April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Physics

Superfast light source made from artificial atom April 28th, 2016

Imaging

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Academic/Education

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

The Ottawa Hospital Research Institute uses the ZetaView from Particle Metrix to study membrane microparticles as potential biomarkers for underlying diseases April 12th, 2016

FEI Partners with Five Pharmaceutical Companies, the Medical Research Council and the University of Cambridge to form Cryo-EM Research Consortium April 5th, 2016

SUNY Poly, in Collaboration with the George Washington School of Medicine and Health Sciences and Stony Brook University, Demonstrates Pioneering Method to Visualize and Identify Engineered Nanoparticles in Tissue March 25th, 2016

Announcements

Hybrid nanoantennas -- next-generation platform for ultradense data recording April 28th, 2016

Superfast light source made from artificial atom April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Tools

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

Chemists use DNA to build the world's tiniest thermometer April 27th, 2016

Bruker Introduces First of Its Kind Dimensional Analysis System: The Novel Contour CMM™ System Fully Integrates 3D Coordinate Measurements with Nanoscale Surface Height, Texture, Waviness and Form Characterization April 26th, 2016

Bruker Introduces Dimension FastScan Pro Industrial AFM: Providing Nanometer-Resolution at High Scan Rates for up to 300-mm Samples April 26th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic