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An Iranian researcher presented an appropriate and quick method based on electrochemical methods by synthesizing carbon nanotube modified electrode to measure carbidopa drug in the treatment of Parkinson's disease.
This measurement method can be used in the related medical industries, in the standardization industries for this very medicine, and in the centers and laboratories that need to determine the concentration of the medicine in biological media in order to diagnose the disease.
"Two objectives were being pursued in this research," said Dr. Mohaddesi, one of the researchers of the plan, "The first objective was to extend the applications of carbon nanotubes in the production of modified electrodes and to display the abilities of such nanomaterials in increasing the sensitivity and selectivity of the chemical modified electrodes. The second objective was to present a suitable and rapid method in order to measure carbidopa medicine based on electrochemical methods."
According to the results of the experiments, the use of carbon nanotube in the electrode structure results in completely modified electrochemical responses. Increase in electrolysis signals is another effect of the carbon nanotubes, which is one of the important parameters in increasing the sensitivity of this method.
Dr. Mohaddesi pointed out to another finding in this research, and said, "The use of carbon nanotube showed desirable results in the measurement of carbidopa at very low concentrations. Among the results of this research, mention can be made of the measurement of carbidopa at concentration range of 6.0-100 micromoles, diagnosis range of 0.4 micromoles, and repeatability of less than 3%.
The research has been published in 2012 in International Journal of Electrochemical Science.
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