Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Nanostructured Sensors Power Novel Cancer Detection System

Abstract:
Using a sensor made of densely packed carbon nanotubes coated with gold nanoparticles, a researcher team headed by James Rusling of the University of Connecticut has developed a low-cost microfluidic device for detecting oral cancer. According to the researchers, the device is readily adaptable to detecting other cancers.

Nanostructured Sensors Power Novel Cancer Detection System

Bethesda, MD | Posted on July 2nd, 2012

Tests on samples obtained from 78 oral cancer patients and 49 control subjects showed that the device has a clinical sensitivity of 89% and specificity of 98% for detecting oral cancer. Dr. Rusling and his collaborators published their results in the journal Analytical Chemistry. While other groups have also developed analytical methods that produce similar promise for detecting blood-borne biomarkers of oral cancer, these methods are based on time-consuming and expensive technologies.

The microfluidic device that Dr. Rusling's team developed simultaneously detects extraordinarily low levels of four proteins that together provide a diagnostic signature for oral cancer. Magnetic beads, each coated with 120,000 antibody molecules, are used to capture even trace levels of specific biomarker proteins and remove them from a blood sample. The magnetic particles are then injected into the microfluidic device, which flows the beads over the sensor elements. Each sensor's electrical output corresponds to blood levels of a specific protein.

According to the investigators, the entire assay takes 50 minutes to perform. Each disposable carbon nanotube sensor chip costs about $9. The readout device uses available electronic components and pumps that together cost under $26,000, which "makes this approach accessible to virtually any biomedical laboratory at a small cost."

####

About The National Cancer Institute (NCI)
To help meet the goal of reducing the burden of cancer, the National Cancer Institute (NCI), part of the National Institutes of Health, is engaged in efforts to harness the power of nanotechnology to radically change the way we diagnose, treat and prevent cancer.

The NCI Alliance for Nanotechnology in Cancer is a comprehensive, systematized initiative encompassing the public and private sectors, designed to accelerate the application of the best capabilities of nanotechnology to cancer.

Currently, scientists are limited in their ability to turn promising molecular discoveries into benefits for cancer patients. Nanotechnology can provide the technical power and tools that will enable those developing new diagnostics, therapeutics, and preventives to keep pace with today’s explosion in knowledge.

For more information, please click here

Contacts:
National Cancer Institute
Office of Technology & Industrial Relations
ATTN: NCI Alliance for Nanotechnology in Cancer
Building 31, Room 10A49
31 Center Drive , MSC 2580
Bethesda , MD 20892-2580

Copyright © The National Cancer Institute (NCI)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

View abstract - "Ultrasensitive detection of cancer biomarkers in the clinic using a nanostructured microfluidic assay."

Related News Press

News and information

Self-assembling 3D battery would charge in seconds May 22nd, 2018

Supersonic waves may help electronics beat the heat May 18th, 2018

New blood test rapidly detects signs of pancreatic cancer May 17th, 2018

Disability Can Be a Superpower in Space Disabled astronauts offer unique solutions to emergencies in space May 17th, 2018

Microfluidics/Nanofluidics

Leti to Demo New Curving Technology at Photonics West that Improves Performance of Optical Components January 18th, 2018

Nanotubes go with the flow to penetrate brain tissue: Rice University scientists, engineers develop microfluidic devices, microelectrodes for gentle implantation December 19th, 2017

Leti Develops World’s First Micro-Coolers for CERN Particle Detectors: Leti Design, Fabrication and Packaging Expertise Extends to Very Large Scientific Instruments December 11th, 2017

Using light to propel water : With new method, MIT engineers can control and separate fluids on a surface using only visible light April 25th, 2017

Govt.-Legislation/Regulation/Funding/Policy

Self-assembling 3D battery would charge in seconds May 22nd, 2018

Supersonic waves may help electronics beat the heat May 18th, 2018

New blood test rapidly detects signs of pancreatic cancer May 17th, 2018

Deeper understanding of quantum chaos may be the key to quantum computers May 16th, 2018

Nanotubes/Buckyballs/Fullerenes/Nanorods

Making carbon nanotubes as usable as common plastics: Researchers discover that cresols disperse carbon nanotubes at unprecedentedly high concentrations May 15th, 2018

'Exceptional' research points way toward quantum discoveries: Rice University scientists make tunable light-matter couplings in nanotube films April 30th, 2018

The first PE blown films with nanotubes hit the Chinese market April 26th, 2018

Plasmons triggered in nanotube quantum wells: Rice, Tokyo Metropolitan scientists create platform for unique near-infrared devices March 16th, 2018

Nanomedicine

New blood test rapidly detects signs of pancreatic cancer May 17th, 2018

Elastic microspheres expand understanding of embryonic development and cancer cells May 15th, 2018

Nanomedicine -- Targeting cancer cells with sugars May 14th, 2018

NanoBio Announces Corporate Name Change to BlueWillow Biologics and Closes $10M Series A Financing: Move Reflects Focus on Advancing Several Intranasal Vaccines to Human Studies May 9th, 2018

Sensors

Strain improves performance of atomically thin semiconductor material May 11th, 2018

Salt boosts creation of 2-D materials: Rice University scientists show how salt lowers reaction temperatures to make novel materials April 18th, 2018

Doing the nano-shimmy: New device modulates light and amplifies tiny signals April 12th, 2018

Scientists Use Nanotechnology to Detect Molecular Biomarker for Osteoarthritis March 13th, 2018

Discoveries

Self-assembling 3D battery would charge in seconds May 22nd, 2018

Supersonic waves may help electronics beat the heat May 18th, 2018

New blood test rapidly detects signs of pancreatic cancer May 17th, 2018

Deeper understanding of quantum chaos may be the key to quantum computers May 16th, 2018

Announcements

Self-assembling 3D battery would charge in seconds May 22nd, 2018

Supersonic waves may help electronics beat the heat May 18th, 2018

New blood test rapidly detects signs of pancreatic cancer May 17th, 2018

Disability Can Be a Superpower in Space Disabled astronauts offer unique solutions to emergencies in space May 17th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project