Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Leonardo Biosystems and NanoMedical Systems Sign Collaboration Deal for Manufacturing Scale Up of Leonardo's Drug Delivery Nanoparticles

Abstract:
Leonardo Biosystems, Inc. and NanoMedical Systems, Inc. (NMS), two emerging drug delivery companies, today announced that they have signed a development contract in which NMS will develop and establish a commercial process to manufacture nanoporous silicon particles for Leonardo's multi-stage drug delivery system.
"The expertise in the fabrication of massively-parallel nanofluidic structures in silicon gained in the development of our own drug delivery products enables us to support Leonardo in bringing their manufacturing process to a commercial performance level," said Randy Goodall, President and CEO of NanoMedical Systems. "Our medical device engineering quality system is designed to produce an FDA-compliant process that will bring Leonardo to the doorstep of clinical testing of their innovative drug delivery products."

Leonardo Biosystems and NanoMedical Systems Sign Collaboration Deal for Manufacturing Scale Up of Leonardo's Drug Delivery Nanoparticles

Houston and Austin, TX | Posted on November 28th, 2011

With the support of university researchers and NMS, Leonardo has formed prototype particles, demonstrating all the necessary unit processes to make the particles. Under the collaboration, NMS will engineer, refine, and integrate these steps in a manner that prepares Leonardo for manufacturing particles suitable for clinical trials.

"NMS's familiarity with silicon materials and their capability to do the work under an FDA-compliant quality system makes them an ideal partner," said Bruce D. Given, M.D., CEO of Leonardo Biosystems. "Creation of a commercial-scale manufacturing process compliant with regulatory requirements is on the critical path for Leonardo to translate its exciting animal proof of concept data into clinical reality. With NMS as a partner, we look forward to moving ahead aggressively with our development program."

####

About Arrowhead Research Corporation
About Leonardo's multi-stage system
Leonardo's lead technology consists of fully biodegradable, porous silicon particles smaller than a red blood cell, which can be loaded with a diverse array of secondary nanoparticles such as liposomes, micelles, carbon nanotubes, dendrimers and metallic nanoparticles. In addition to bypassing many of the body's natural defenses that lead to rapid clearance of nanoparticles administered alone, Leonardo's particles can be designed to seek out tumor vasculature and can be tuned to create an intravascular depot, providing sustained release following a single intravenous injection.


About Leonardo Biosystems, Inc.
Leonardo Biosystems is a drug delivery company built around technology developed by Dr. Mauro Ferrari, one of the world's best-known nano-science innovators. Leonardo has a multi-stage delivery platform that has been shown in animal models to be highly effective in targeting delivery of siRNA and small molecule drugs. Leonardo is a portfolio company of Arrowhead Research Corporation (NASDAQ: ARWR, NASDAQ: ARWRD). For more information, please visit www.leonardobiosystems.com.

About NanoMedical Systems, Inc.

NanoMedical Systems is a privately held, drug delivery company developing implantable devices that use silicon nanochannel technology invented by Dr. Mauro Ferrari, an original innovator in the field of Bio-MEMS. NanoMedical Systems implant platform, the Personalized Molecular Drug-delivery System includes a first generation device (PMDS-1) customizable for months of constant release of a wide range of drug and biologic molecules with a second generation device (PMDS-2) that will provide variable controlled release via programming, remote control, and sensors. The PMDS-1 has demonstrated the sustained delivery of therapeutics from small molecules to peptides and proteins in both in vitro and in vivo studies. For more information, please visit www.NanoMedSys.com.

For more information, please click here

Contacts:
Investor Relations Contact:
Brandi Floberg or Kathy Price
The Piacente Group, Inc.
212-481-2050

Copyright © Arrowhead Research Corporation

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Microfluidics/Nanofluidics

Toward a new way to keep electronics from overheating July 2nd, 2014

New particle-sorting method breaks speed records: Discovery could lead to new ways of detecting cancer cells or purifying contaminated water July 1st, 2014

Micro-manufacturing breakthrough is wired for sound June 24th, 2014

Fully automated DNA lab-on-a-chip microfluidic system wins Dolomite’s Productizing Science® competition 2013 June 10th, 2014

Nanotubes/Buckyballs

SouthWest NanoTechnologies Names NanoSperse as A SWeNT Certified Compounder July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

UCF Nanotech Spinout Developing Revolutionary Battery Technology: Power the Next Generation of Electronics with Carbon July 23rd, 2014

University of Houston researchers create new method to draw molecules from live cells: Technique using magnetic nanomaterials offers promise for diagnosis, gene therapy July 17th, 2014

Nanomedicine

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

FEI adds Phase Plate Technology and Titan Halo TEM to its Structural Biology Product Portfolio: New solutions provide the high-quality imaging and contrast necessary to analyze the 3D structure of molecules and molecular complexes July 28th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Announcements

Tough foam from tiny sheets: Rice University lab uses atom-thick materials to make ultralight foam July 29th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

A new way to make microstructured surfaces: Method can produce strong, lightweight materials with specific surface properties July 29th, 2014

Alliances/Partnerships/Distributorships

SouthWest NanoTechnologies Names NanoSperse as A SWeNT Certified Compounder July 29th, 2014

ACS Biomaterials Science & Engineering™: Brand-new journal names editor July 29th, 2014

A*STAR and industry form S$200M semiconductor R&D July 25th, 2014

Organometallics welcomes new editor-in-chief: Paul Chirik, Ph.D. July 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE