Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Researchers Link DNA to Nanostructures

Jin-Woo Kim, University of Arkansas
Jin-Woo Kim, University of Arkansas

Abstract:
Assembly of nanostructures using DNA may lead to the production of new materials with a wide range of applications from electronics to tissue engineering. Researchers in the Institute for Nanoscience and Engineering at the University of Arkansas have produced building blocks for such material by controlling the number, placement and orientation of DNA linkers on the surface of colloidal nanoparticles.

Researchers Link DNA to Nanostructures

Fayetteville, AR | Posted on September 20th, 2011

Their work is featured as the "hot paper" in the current issue of Angewandte Chemie International Edition, the weekly scientific journal of the German Chemical Society.

"We have demonstrated a strategy to place ‘DNA linkers' on a nanoparticle at specific angles relative to each other so that we may produce building blocks with well-defined arrangements of DNA in all dimensions," said Jin-Woo Kim, professor of biological engineering. "The specific number and orientation of DNA strands on the nanoparticles allow greater control over the ultimate shape of nanostructures."

DNA linkers are areas on the nanoparticles that functionally allow connection with other nanoparticles. In this case, connection is achieved through a type of DNA hybridization reaction.

The simple and sustainable strategy involves attaching strands of DNA to functionalized nanoparticles one strand after the other rather than all at the same time. The nanoparticle with the first strand serves as the starting material for the second strand. The nanoparticle with these two strands together serves as the starting material for the third, and so on. In addition to facilitating greater control over the shape of the structure, assembling in this sequential manner renders the process more reproducible and scalable, which helps with the assembly of complex, hybrid nanoscale architectures at all scales and in all dimensions.

The building blocks, which the researchers call "nBLOCKs," remained stable under volatile conditions. They exhibited chemical stability and water solubility during ligand replacement reactions. There were no apparent changes in physical and chemical properties when the building blocks were stored at 4 degrees Celsius for at least a month. Such promising stability shows high potential for their practical application. The researchers continue working on further optimizing their physical and chemical stability.

Kim said the building strategy can be generalized for other types of nanoparticles, meaning that construction of other types of building blocks with specific, desired functions may be achieved. The technology has the potential to transform many fields of research, including biology, medicine, chemistry, physics, materials science and engineering.

The research was supported by the National Science Foundation, the University of Arkansas Division of Agriculture and the Arkansas Biosciences Institute.

The work was a multidisciplinary, collaborative effort with Russell Deaton, professor of computer science and computer engineering. Jeong-Hwan Kim, postdoctoral associate at the Bio/Nano Technology Laboratory, also made a significant contribution to the project.

Jin-Woo Kim is a professor in the Dale Bumpers College of Agricultural, Food and Life Sciences and the College of Engineering. He works in the Institute for Nanoscience and Engineering at the University of Arkansas and directs the Bio/Nano Technology Laboratory.

####

For more information, please click here

Contacts:
Jin-Woo Kim
professor
Biological and Agricultural Engineering
479-575-3402


Matt McGowan
science and research
communications officer
University Relations
479-575-4246

Copyright © Newswise

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Chemical interactions between silver nanoparticles and thiols: A comparison of mercaptohexanol again September 30th, 2014

A Heartbeat Away? Hybrid "Patch" Could Replace Transplants: TAU researcher harnesses gold nanoparticles to engineer novel biocompatible cardiac patch September 30th, 2014

Iranian Scientists Determine Grain Size, Minimize Time of Nanocomposite Synthesis September 29th, 2014

Nanoparticles Used to Improve Quality of Bone Cement September 29th, 2014

Chemistry

Chemical interactions between silver nanoparticles and thiols: A comparison of mercaptohexanol again September 30th, 2014

Production of Organometallic Frameworks in Least Possible Time September 23rd, 2014

Physics

Brookhaven Lab's National Synchrotron Light Source II Approved to Start Routine Operations: Milestone marks transition to exciting new chapter September 23rd, 2014

Toward optical chips: A promising light source for optoelectronic chips can be tuned to different frequencies September 19th, 2014

Elusive Quantum Transformations Found Near Absolute Zero: Brookhaven Lab and Stony Brook University researchers measured the quantum fluctuations behind a novel magnetic material's ultra-cold ferromagnetic phase transition September 15th, 2014

Govt.-Legislation/Regulation/Funding/Policy

A Heartbeat Away? Hybrid "Patch" Could Replace Transplants: TAU researcher harnesses gold nanoparticles to engineer novel biocompatible cardiac patch September 30th, 2014

How things coil: Researchers discover that simulation technology designed for Hollywood can be used as a predictive tool for understanding fundamental engineering problems September 29th, 2014

UT Arlington researchers develop transparent nanoscintillators for radiation detection for medical safety and homeland security September 29th, 2014

'Pixel' engineered electronics have growth potential: Rice, Oak Ridge, Vanderbilt, Penn scientists lead creation of atom-scale semiconducting composites September 29th, 2014

Nanomedicine

A Heartbeat Away? Hybrid "Patch" Could Replace Transplants: TAU researcher harnesses gold nanoparticles to engineer novel biocompatible cardiac patch September 30th, 2014

How things coil: Researchers discover that simulation technology designed for Hollywood can be used as a predictive tool for understanding fundamental engineering problems September 29th, 2014

Nanoparticles Used to Improve Quality of Bone Cement September 29th, 2014

Teijin Aramid’s carbon nanotube fibers awarded with Paul Schlack prize: New generation super fibers bring wave of innovations to fiber market September 25th, 2014

Discoveries

Chemical interactions between silver nanoparticles and thiols: A comparison of mercaptohexanol again September 30th, 2014

A Heartbeat Away? Hybrid "Patch" Could Replace Transplants: TAU researcher harnesses gold nanoparticles to engineer novel biocompatible cardiac patch September 30th, 2014

Iranian Scientists Determine Grain Size, Minimize Time of Nanocomposite Synthesis September 29th, 2014

Nanoparticles Used to Improve Quality of Bone Cement September 29th, 2014

Materials/Metamaterials

How things coil: Researchers discover that simulation technology designed for Hollywood can be used as a predictive tool for understanding fundamental engineering problems September 29th, 2014

Iranian Scientists Determine Grain Size, Minimize Time of Nanocomposite Synthesis September 29th, 2014

Nanoparticles Used to Improve Quality of Bone Cement September 29th, 2014

Production of Anticorrosive Chromate Nanocoatings in Iran September 27th, 2014

Announcements

Chemical interactions between silver nanoparticles and thiols: A comparison of mercaptohexanol again September 30th, 2014

A Heartbeat Away? Hybrid "Patch" Could Replace Transplants: TAU researcher harnesses gold nanoparticles to engineer novel biocompatible cardiac patch September 30th, 2014

Iranian Scientists Determine Grain Size, Minimize Time of Nanocomposite Synthesis September 29th, 2014

Nanoparticles Used to Improve Quality of Bone Cement September 29th, 2014

Nanobiotechnology

How things coil: Researchers discover that simulation technology designed for Hollywood can be used as a predictive tool for understanding fundamental engineering problems September 29th, 2014

Penn Team Studies Nanocrystals by Passing Them Through Tiny Pores September 26th, 2014

Graphene and Amaranthus Superparamagnets: Breakthrough nanoparticles discovery of Indian researcher September 23rd, 2014

New NIH/DOE Grant for Life Science Studies at NSLS-II: Funding will support operation of three powerful experimental stations designed to reveal detailed structures of proteins, viruses, and more September 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE