Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Researchers Link DNA to Nanostructures

Jin-Woo Kim, University of Arkansas
Jin-Woo Kim, University of Arkansas

Abstract:
Assembly of nanostructures using DNA may lead to the production of new materials with a wide range of applications from electronics to tissue engineering. Researchers in the Institute for Nanoscience and Engineering at the University of Arkansas have produced building blocks for such material by controlling the number, placement and orientation of DNA linkers on the surface of colloidal nanoparticles.

Researchers Link DNA to Nanostructures

Fayetteville, AR | Posted on September 20th, 2011

Their work is featured as the "hot paper" in the current issue of Angewandte Chemie International Edition, the weekly scientific journal of the German Chemical Society.

"We have demonstrated a strategy to place ‘DNA linkers' on a nanoparticle at specific angles relative to each other so that we may produce building blocks with well-defined arrangements of DNA in all dimensions," said Jin-Woo Kim, professor of biological engineering. "The specific number and orientation of DNA strands on the nanoparticles allow greater control over the ultimate shape of nanostructures."

DNA linkers are areas on the nanoparticles that functionally allow connection with other nanoparticles. In this case, connection is achieved through a type of DNA hybridization reaction.

The simple and sustainable strategy involves attaching strands of DNA to functionalized nanoparticles one strand after the other rather than all at the same time. The nanoparticle with the first strand serves as the starting material for the second strand. The nanoparticle with these two strands together serves as the starting material for the third, and so on. In addition to facilitating greater control over the shape of the structure, assembling in this sequential manner renders the process more reproducible and scalable, which helps with the assembly of complex, hybrid nanoscale architectures at all scales and in all dimensions.

The building blocks, which the researchers call "nBLOCKs," remained stable under volatile conditions. They exhibited chemical stability and water solubility during ligand replacement reactions. There were no apparent changes in physical and chemical properties when the building blocks were stored at 4 degrees Celsius for at least a month. Such promising stability shows high potential for their practical application. The researchers continue working on further optimizing their physical and chemical stability.

Kim said the building strategy can be generalized for other types of nanoparticles, meaning that construction of other types of building blocks with specific, desired functions may be achieved. The technology has the potential to transform many fields of research, including biology, medicine, chemistry, physics, materials science and engineering.

The research was supported by the National Science Foundation, the University of Arkansas Division of Agriculture and the Arkansas Biosciences Institute.

The work was a multidisciplinary, collaborative effort with Russell Deaton, professor of computer science and computer engineering. Jeong-Hwan Kim, postdoctoral associate at the Bio/Nano Technology Laboratory, also made a significant contribution to the project.

Jin-Woo Kim is a professor in the Dale Bumpers College of Agricultural, Food and Life Sciences and the College of Engineering. He works in the Institute for Nanoscience and Engineering at the University of Arkansas and directs the Bio/Nano Technology Laboratory.

####

For more information, please click here

Contacts:
Jin-Woo Kim
professor
Biological and Agricultural Engineering
479-575-3402


Matt McGowan
science and research
communications officer
University Relations
479-575-4246

Copyright © Newswise

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

SUNY Polytechnic Institute Invites the Public to Attend its Popular Statewide 'NANOvember' Series of Outreach and Educational Events October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Chemistry

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Could I squeeze by you? Ames Laboratory scientists model molecular movement within narrow channels of mesoporous nanoparticles October 21st, 2014

Physics

Solid nanoparticles can deform like a liquid: Unexpected finding shows tiny particles keep their internal crystal structure while flexing like droplets October 12th, 2014

Unconventional photoconduction in an atomically thin semiconductor: New mechanism of photoconduction could lead to next-generation excitonic devices October 9th, 2014

Nanoparticles Break the Symmetry of Light October 6th, 2014

Quantum environmentalism: Putting a qubit's surroundings to good use October 2nd, 2014

Govt.-Legislation/Regulation/Funding/Policy

Novel Rocket Design Flight Tested: New Rocket Propellant and Motor Design Offers High Performance and Safety October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Brookhaven Lab Launches Computational Science Initiative:Leveraging computational science expertise and investments across the Laboratory to tackle "big data" challenges October 22nd, 2014

Bipolar Disorder Discovery at the Nano Level: Tiny structures found in brain synapses help scientists better understand disorder October 22nd, 2014

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Materials/Metamaterials

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Researchers patent a nanofluid that improves heat conductivity October 22nd, 2014

Materials for the next generation of electronics and photovoltaics: MacArthur Fellow develops new uses for carbon nanotubes October 21st, 2014

Super stable garnet ceramics may be ideal for high-energy lithium batteries October 21st, 2014

Announcements

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Nanobiotechnology

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Mechanism behind nature's sparkles revealed October 22nd, 2014

‘Designer’ nanodevice could improve treatment options for cancer sufferers October 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE