Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Researcher Bilgicer using nanotechnology to improve cancer treatment

Basar Bilgicer, assistant professor of chemical and biomolecular engineering
Basar Bilgicer, assistant professor of chemical and biomolecular engineering

Abstract:
Research directed by Basar Bilgicer, assistant professor of chemical and biomolecular engineering and a member of the Advanced Diagnostics and Therapeutics initiative at the University of Notre Dame, could one day enable clinicians to deliver powerful chemotherapy drugs to tumors without deleterious side effects.

Researcher Bilgicer using nanotechnology to improve cancer treatment

Notre Dame, IN | Posted on December 6th, 2010

Although chemotherapeutic agents are poisonous to tumors, they also can kill healthy cells, leading to toxic side effects.

Bilgicer's research involves developing drug-loaded nanoparticles to target the tumor tissue, so that the chemotherapeutic agents can be delivered specifically to the tumors rather than healthy tissue.

His studies are based on the fact that nanoparticles accumulated in the tumor tissue, whose leaky blood vessels allowed the nanoparticles to pass out of the capillaries that feed the tumor. While the nanoparticles are small enough to penetrate the tumor tissue, they are too large to pass into other tissues in vital organs such as the kidneys, lungs, liver or spleen. Once the molecule is firmly lodged in the tumor, the higher acidity of the tumor environment causes the release of the chemotherapeutic load, thereby dumping its toxicity fully on cancerous tissues rather than traveling to healthy cells.

Although Bilgicer's studies have primarily been in blood cancers, he notes that the nanoparticles also have application in lung and breast cancers. The nanoparticles will require further development and clinical trials before they are ready for patient care.

Bilgicer will be collaborating with Rudolph Navari, director of Notre Dame's Walter Cancer Institute and assistant dean of the Indiana University School of Medicine South Bend, to study the compound's possible uses in oncology treatment.

####

For more information, please click here

Contacts:
Basar Bilgicer
574-631-1429

Copyright © University of Notre Dame

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoscale view of energy storage January 16th, 2017

Seeing the quantum future... literally: What if big data could help you see the future and prevent your mobile phone from breaking before it happened? January 16th, 2017

NUS researchers achieve major breakthrough in flexible electronics: New classes of printable electrically conducting polymer materials make better electrodes for plastic electronics and advanced semiconductor devices January 14th, 2017

Manchester scientists tie the tightest knot ever achieved January 13th, 2017

Nanoscale Modifications can be used to Engineer Electrical Contacts for Nanodevices January 13th, 2017

Videos/Movies

Manchester scientists tie the tightest knot ever achieved January 13th, 2017

Captured on video: DNA nanotubes build a bridge between 2 molecular posts: Research may lead to new lines of direct communication with cells January 9th, 2017

Possible Futures

Nanoscale view of energy storage January 16th, 2017

Seeing the quantum future... literally: What if big data could help you see the future and prevent your mobile phone from breaking before it happened? January 16th, 2017

NUS researchers achieve major breakthrough in flexible electronics: New classes of printable electrically conducting polymer materials make better electrodes for plastic electronics and advanced semiconductor devices January 14th, 2017

Nanoscale Modifications can be used to Engineer Electrical Contacts for Nanodevices January 13th, 2017

Academic/Education

Oxford Nanoimaging report on how the Nanoimager, a desktop microscope delivering single molecule, super-resolution performance, is being applied at the MRC Centre for Molecular Bacteriology & Infection November 22nd, 2016

The University of Applied Sciences in Upper Austria uses Deben tensile stages as an integral part of their computed tomography research and testing facility October 18th, 2016

Enterprise In Space Partners with Sketchfab and 3D Hubs for NewSpace Education October 13th, 2016

New Agricultural Research Center Debuts at UCF October 12th, 2016

Nanomedicine

New active filaments mimic biology to transport nano-cargo: A new design for a fully biocompatible motility engine transports colloidal particles faster than diffusion with active filaments January 11th, 2017

Keystone Nano Announces FDA Approval Of Investigational New Drug Application For Ceramide NanoLiposome For The Improved Treatment Of Cancer January 10th, 2017

Captured on video: DNA nanotubes build a bridge between 2 molecular posts: Research may lead to new lines of direct communication with cells January 9th, 2017

Arrowhead Provides Response to New Minority Shareholder Announcement January 7th, 2017

Announcements

Nanoscale view of energy storage January 16th, 2017

Seeing the quantum future... literally: What if big data could help you see the future and prevent your mobile phone from breaking before it happened? January 16th, 2017

NUS researchers achieve major breakthrough in flexible electronics: New classes of printable electrically conducting polymer materials make better electrodes for plastic electronics and advanced semiconductor devices January 14th, 2017

Nanoscale Modifications can be used to Engineer Electrical Contacts for Nanodevices January 13th, 2017

Nanobiotechnology

Nanoscale Modifications can be used to Engineer Electrical Contacts for Nanodevices January 13th, 2017

New active filaments mimic biology to transport nano-cargo: A new design for a fully biocompatible motility engine transports colloidal particles faster than diffusion with active filaments January 11th, 2017

Keystone Nano Announces FDA Approval Of Investigational New Drug Application For Ceramide NanoLiposome For The Improved Treatment Of Cancer January 10th, 2017

Captured on video: DNA nanotubes build a bridge between 2 molecular posts: Research may lead to new lines of direct communication with cells January 9th, 2017

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project