Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Researcher Bilgicer using nanotechnology to improve cancer treatment

Basar Bilgicer, assistant professor of chemical and biomolecular engineering
Basar Bilgicer, assistant professor of chemical and biomolecular engineering

Abstract:
Research directed by Basar Bilgicer, assistant professor of chemical and biomolecular engineering and a member of the Advanced Diagnostics and Therapeutics initiative at the University of Notre Dame, could one day enable clinicians to deliver powerful chemotherapy drugs to tumors without deleterious side effects.

Researcher Bilgicer using nanotechnology to improve cancer treatment

Notre Dame, IN | Posted on December 6th, 2010

Although chemotherapeutic agents are poisonous to tumors, they also can kill healthy cells, leading to toxic side effects.

Bilgicer's research involves developing drug-loaded nanoparticles to target the tumor tissue, so that the chemotherapeutic agents can be delivered specifically to the tumors rather than healthy tissue.

His studies are based on the fact that nanoparticles accumulated in the tumor tissue, whose leaky blood vessels allowed the nanoparticles to pass out of the capillaries that feed the tumor. While the nanoparticles are small enough to penetrate the tumor tissue, they are too large to pass into other tissues in vital organs such as the kidneys, lungs, liver or spleen. Once the molecule is firmly lodged in the tumor, the higher acidity of the tumor environment causes the release of the chemotherapeutic load, thereby dumping its toxicity fully on cancerous tissues rather than traveling to healthy cells.

Although Bilgicer's studies have primarily been in blood cancers, he notes that the nanoparticles also have application in lung and breast cancers. The nanoparticles will require further development and clinical trials before they are ready for patient care.

Bilgicer will be collaborating with Rudolph Navari, director of Notre Dame's Walter Cancer Institute and assistant dean of the Indiana University School of Medicine South Bend, to study the compound's possible uses in oncology treatment.

####

For more information, please click here

Contacts:
Basar Bilgicer
574-631-1429

Copyright © University of Notre Dame

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoparticles present sustainable way to grow food crops May 1st, 2016

Searching for a nanotech self-organizing principle May 1st, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Videos/Movies

WiFi capacity doubled at less than half the size: Columbia Engineers develop the first on-chip RF circulator that doubles WiFi speeds with a single antenna -- could transform telecommunications April 18th, 2016

First-ever videos show how heat moves through materials at the nanoscale and speed of sound: Groundbreaking observations could help develop better, more efficient materials for electronics and alternative energy April 16th, 2016

Nanotubes assemble! Rice introduces 'Teslaphoresis' Reconfigured Tesla coil aligns, electrifies materials from a distance April 15th, 2016

Record-breaking steel could be used for body armor, shields for satellites April 7th, 2016

Possible Futures

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Exploring phosphorene, a promising new material April 29th, 2016

Academic/Education

JPK reports on the use of a NanoWizard AFM system at the University of Kaiserslautern to study the interaction of bacteria with microstructured surfaces April 28th, 2016

The Ottawa Hospital Research Institute uses the ZetaView from Particle Metrix to study membrane microparticles as potential biomarkers for underlying diseases April 12th, 2016

FEI Partners with Five Pharmaceutical Companies, the Medical Research Council and the University of Cambridge to form Cryo-EM Research Consortium April 5th, 2016

SUNY Poly, in Collaboration with the George Washington School of Medicine and Health Sciences and Stony Brook University, Demonstrates Pioneering Method to Visualize and Identify Engineered Nanoparticles in Tissue March 25th, 2016

Nanomedicine

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

Announcements

Nanoparticles present sustainable way to grow food crops May 1st, 2016

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Cooling graphene-based film close to pilot-scale production April 30th, 2016

Personal cooling units on the horizon April 29th, 2016

Nanobiotechnology

Clay nanotube-biopolymer composite scaffolds for tissue engineering May 1st, 2016

Nanoparticles hold promise as double-edged sword against genital herpes April 28th, 2016

Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016

The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic