Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Popular nanoparticle causes toxicity in fish, study shows

Abstract:
A nanoparticle growing in popularity as a bactericidal agent has been shown to be toxic to fish, according to a Purdue University study.

By Brian Wallheimer

Popular nanoparticle causes toxicity in fish, study shows

West Lafayette, IN | Posted on March 2nd, 2010

Tested on fathead minnows - an organism often used to test the effects of toxicity on aquatic life -- nanosilver suspended in solution proved toxic and even lethal to the minnows. When the nanosilver was allowed to settle, the solution became several times less toxic but still caused malformations in the minnows.

"Silver nitrate is a lot more toxic than nanosilver, but when nanosilver was sonicated, or suspended, its toxicity increased tenfold," said Maria Sepúlveda, an assistant professor of forestry and natural resources whose findings were published in the journal Ecotoxicology. "There is reason to be concerned."

Sepúlveda and doctoral student Geoff Laban exposed fathead minnows to nanosilver at several stages of their development, from embryo to the point where they swim up from the bottom of their habitats to eat for the first time. Even without sonication, nanosilver caused malformations that included head hemorrhages and edema, and ultimately proved lethal.

Using electron microscopy, Sepúlveda was able to detect nanosilver particles measuring 30 nanometers or less inside the minnow embryos. Thirty nanometers is more than 3,000 times smaller than the diameter of a human hair.

"These nanosilver particles are so small they are able to cross the egg membranes and move into the fish embryos in less than a day," Sepúlveda said. "They had a potentially high dose of silver in them."

Nanosilver is growing in popularity as a component of many products. It is used to kill bacteria in goods such as odor-control clothing, countertops, cutting boards and detergents. Currently, there are few regulations for nanosilver's applications in products, but Ron Turco, professor of agronomy and the paper's co-author, said the Environmental Protection Agency is reviewing the situation.

Turco also indicated there has been little work done to estimate the current level of nanosilver being released into the environment.

"Silver has been used in the past as an antimicrobial agent. It's a known toxicant to microorganisms," he said. "Nanosilver is being considered by the EPA for environmental exposure profiling, much like a pesticide."

Turco said it's unclear how nanosilver exposure might affect human health; however, he said that silver solutions have been considered by some to be a probiotic, and low dosages are sometimes consumed for intestinal health.

"The use of nanosilver could provide a number of sanitary benefits if used properly," Turco said. "However, the indiscriminate inclusion of nanosilver into products to simply allow them to say they are antimicrobial is creating a cautionary issue."

Sepúlveda said she plans to develop tests to understand the effect different nanoparticles have on fish and other organisms. She also wants to develop testing to determine nanosilver concentrations in the environment.

"How are we going to know the risk unless we know the concentration of these particles?" Sepúlveda said.

Purdue University's Discovery Park funded the research.


ABSTRACT

The Effects of Silver Nanoparticles on Fathead Minnow (Pimephales Promelas) Embryos

Geoff Laban, Loring F. Niles, Ronald F. Turco, John W. Bickham and Maria S. Sepúlveda

Nanoparticles are being used in many commercial applications. We describe the toxicity of two commercial silver (Ag) nanoparticle (NP) products, NanoAmor and Sigma on Pimephales promelas embryos. Embryos were exposed to varying concentrations of either sonicated or stirred NP solutions for 96 h. LC50 values for NanoAmor and Sigma Ag NPs were 9.4 and 10.6 mg/L for stirred and 1.25 and 1.36 mg/L for sonicated NPs, respectively. Uptake of Ag NPs into the embryos was observed after 24 h using Transmission Electron Microscopy and Ag NPs induced a concentration-dependent increase in larval abnormalities, mostly edema. Dissolved Ag released from Ag NPs was measured using Inductively Coupled-Mass Spectrometry and the effects tested were found to be three times less toxic when compared to Ag nitrate (AgNO3). The percentage of dissolved Ag released was inversely proportional to the concentration of Ag NPs with the lowest (0.625 mg/L) and highest (20 mg/L) concentrations tested releasing 3.7 and 0.45% dissolved Ag, respectively, and percent release was similar regardless if concentrations were stirred or sonicated. Thus increased toxicity after sonication cannot be solely explained by dissolved Ag. We conclude that both dissolved and particulate forms of Ag elicited toxicity to fish embryos.

####

For more information, please click here

Contacts:
Writer:
Brian Wallheimer
765-496-2050


Sources:
Maria Sepúlveda
765-496-3428


Ron Turco
765-494-8077

Copyright © Purdue University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

JPK reports on the use of AFM and the CellHesion module to study plant cells at the University of Queensland November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Preparing for Nano

Durnham University's DEEPEN project comes to a close September 26th, 2012

Technical Seminar at ANFoS 2012 August 22nd, 2012

Nanotechnology shows we can innovate without economic growth April 12th, 2012

Thailand to host NanoThailand 2012 December 18th, 2011

Govt.-Legislation/Regulation/Funding/Policy

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Academic/Education

SUNY Poly Student Awarded Fellowship with the U.S. Department of Energy's Postgraduate Research Program: Ph.D. Candidate Accepts Postmaster's Appointment To Conduct Research At Albany NanoTech Complex November 13th, 2014

SUNY Polytechnic Institute Hosts Massive Crowd of More Than 3,000 People Who Attended Community Day Activities Across New York State: CNSE’s ‘NANOvember’ kickoff event highlights New York State’s growing high-tech sector with open house events in Albany, Utica, and Rochester November 3rd, 2014

SUNY Polytechnic Institute Invites the Public to Attend its Popular Statewide 'NANOvember' Series of Outreach and Educational Events October 23rd, 2014

First Canada Excellence Research Chair gets $10 million from the federal government for oilsands research at the University of Calgary: Federal government announces prestigious research chair to study improving oil production efficiency October 19th, 2014

Materials/Metamaterials

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Aromatic food chemistry to the making of copper nanowires November 24th, 2014

Novel Method Found for Connection of Metallic Alloys to Polymers November 23rd, 2014

Sustainable Nanotechnologies Project November 20th, 2014

Announcements

Renishaw receives Queen's Award for spectroscopy developments November 25th, 2014

JPK reports on the use of AFM and the CellHesion module to study plant cells at the University of Queensland November 25th, 2014

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Environment

Iranian Experts Clean Uranium-Contaminated Water by Nano-Particles November 23rd, 2014

Silver Nanoparticles Produced in Iran from Forest Plants Extract November 20th, 2014

Nano Sorbents Able to Remove Pollutions Caused by Oil Derivatives November 20th, 2014

Application of Nanocomposites in Production of Photocatalysts for Water Treatment November 17th, 2014

Safety-Nanoparticles/Risk management

Sustainable Nanotechnologies Project November 20th, 2014

A gut reaction November 19th, 2014

Nanosafety research – there’s room for improvement October 29th, 2014

Plastic nanoparticles also harm freshwater organisms October 18th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE