Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Thermochemical Nanolithograpy Now Allows Multiple Chemicals on Chip

Abstract:
Scientists at Georgia Tech have developed a nanolithographic technique that can produce high-resolution patterns of at least three different chemicals on a single chip at writing speeds of up to one millimeter per second.

Thermochemical Nanolithograpy Now Allows Multiple Chemicals on Chip

Atlanta, GA | Posted on December 16th, 2009

The chemical nanopatterns can be tailor-designed with any desired shape and have been shown to be sufficiently stable so that they can be stored for weeks and then used elsewhere. The technique, known as Thermochemical Nanolithography is detailed in the December 2009 edition of the journal Advanced Functional Materials. The research has applications in a number of scientific fields from electronics to medicine.

"The strength of this method is really the possibility to produce low-cost, high-resolution and high-density chemical patterns on a sample that can be delivered in any lab around the world, where even non experts in nanotechnology can dip the sample in the desired solution and, for example, make nano-arrays of proteins, DNA or nanoparticles," said Elisa Riedo, associate professor in the School of Physics at the Georgia Institute of Technology.

Conceptually, the technique is surprisingly simple. Using an atomic force microscope (AFM), researchers heat a silicon tip and run it over a thin polymer film. The heat from the tip induces a local chemical reaction at the surface of the film. This reaction changes the film's chemical reactivity and transforms it from an inert surface to a reactive one that can selectively attach other molecules. The team first developed the technique in 2007. Now they've added some important new twists that should make thermochemical nanolithography (TCNL) an extremely useful tool for scientists working at the nanoscale.

"We've created a way to make independent patterns of multiple chemicals on a chip that can be drawn in whatever shape you want," said Jennifer Curtis, assistant professor in the School of Physics.

Being able to create high-resolution features of different chemicals in arbitrary shapes is important because some nanolithography techniques are limited to just one chemistry, lower resolutions and/or fixed shapes. In addition, TCNL's speed capability of one millimeter per second makes it orders of magnitude faster than the widely used dip-pen nanolithography, which routinely clocks at a speed of 0.0001 millimeters per second per pen.

The research is enabled by heated AFM probe tips that can create a hot spot as small as a few nanometers in diameter. Such tips are designed and fabricated by collaborator Professor William King at the University of Illinois, Urbana-Champaign. "The heated tip allows one to direct nano-scale chemical reactions," said King.

The new technique produces multiple chemical patterns on the same chip by using the AFM to heat a polymer film and change its reactivity. The chip is then dipped into a solution, which allows chemicals (for example, proteins or other chemical linkers) in the solution to bind to the chip on the parts where it has been heated. The AFM then heats the film in another spot. The chip is dipped into another solution and again another chemical can bind to the chip.

In the paper, the scientists show they can pattern amine, thiol, aldehyde and biotin using this technique. But in principle TCNL could be used for almost any chemical. Their work also shows that the chemical patterns can be used to organize functional materials at the surface, such as proteins and DNA.

"The power of this technique is that in principle it can work with almost any chemical or chemically reactive nano-object. It allows scientists to very rapidly draw many things that can then be converted to any number of different things, which themselves can bind selectively to yet any number of other things. So, it doesn't matter if you're interested in biology, electronics, medicine or chemistry, TCNL can create the reactive pattern to bind what you choose," said Seth Marder, professor in Tech's School of Chemistry and Biochemistry and director of the Center for Organic Photonics and Electronics.

In addition, TCNL allows the chemical writing to be done in one location with the nano-object patterning in another, so that scientists who aren't experts in writing chemical patterns on the nanoscale can still attach their objects to it. It's the technique's stability that makes this possible.

"Once you draw the pattern, it's very stable and non-reactive. We've shown that you can have it for more than a month, take it out and dip it and it still will bind," said Riedo.

"I would like to think that several years from now people will have access to a TCNL tool that enables them to do this patterning at a place like Georgia Tech, that's much less expensive than the kind of nanolithography tools we currently use in our clean room," said Marder.

The research was supported by the National Science Foundation, the U.S. Department of Energy, the Georgia Institute of Technology, GT Innovative Award, and ONR Nanoelectronics.

####

About Georgia Tech
The Georgia Institute of Technology is one of the nation's premier research universities. Ranked seventh among U.S. News & World Report's top public universities, Georgia Tech's more than 19,000 students are enrolled in its Colleges of Architecture, Computing, Engineering, Liberal Arts, Management and Sciences. Tech is among the nation's top producers of women and African-American engineers. The Institute offers research opportunities to both undergraduate and graduate students and is home to more than 100 interdisciplinary units plus the Georgia Tech Research Institute.

For more information, please click here

Contacts:
David Terraso
Communications and Marketing
404-385-2966

Copyright © Georgia Tech

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Novel 'converter' heralds breakthrough in ultra-fast data processing at nanoscale: Invention bagged four patents and could potentially make microprocessor chips work 1,000 times faster October 20th, 2017

Strange but true: turning a material upside down can sometimes make it softer October 20th, 2017

Leti Coordinating Project to Develop Innovative Drivetrains for 3rd-generation Electric Vehicles: CEA Techís Contribution Includes Litenís Knowhow in Magnetic Materials and Simulation And Letiís Expertise in Wide-bandgap Semiconductors October 20th, 2017

MIPT scientists revisit optical constants of ultrathin gold films October 20th, 2017

Chemistry

What can be discovered at the junction of physics and chemistry October 6th, 2017

Copper catalyst yields high efficiency CO2-to-fuels conversion: Berkeley Lab scientists discover critical role of nanoparticle transformation September 20th, 2017

Chemical hot spots: Scanning tunneling microscopy measurements identify active sites on catalyst surfaces September 7th, 2017

More durable, less expensive fuel cells: University of Delaware researchers have developed a new technology that could speed up the commercialization of fuel cell vehicles September 5th, 2017

Govt.-Legislation/Regulation/Funding/Policy

Leti Coordinating Project to Develop Innovative Drivetrains for 3rd-generation Electric Vehicles: CEA Techís Contribution Includes Litenís Knowhow in Magnetic Materials and Simulation And Letiís Expertise in Wide-bandgap Semiconductors October 20th, 2017

Bringing the atomic world into full color: Researchers turn atomic force microscope measurements into color images October 19th, 2017

Long nanotubes make strong fibers: Rice University researchers advance characterization, purification of nanotube wires and films October 17th, 2017

Spinning strands hint at folding dynamics: Rice University lab uses magnetic beads to model microscopic proteins, polymers October 17th, 2017

Possible Futures

Novel 'converter' heralds breakthrough in ultra-fast data processing at nanoscale: Invention bagged four patents and could potentially make microprocessor chips work 1,000 times faster October 20th, 2017

Bringing the atomic world into full color: Researchers turn atomic force microscope measurements into color images October 19th, 2017

'Find the Lady' in the quantum world: International team of researchers presents method for quantum-mechanical swapping of positions October 18th, 2017

Long nanotubes make strong fibers: Rice University researchers advance characterization, purification of nanotube wires and films October 17th, 2017

Nanomedicine

Spinning strands hint at folding dynamics: Rice University lab uses magnetic beads to model microscopic proteins, polymers October 17th, 2017

Arrowhead Pharmaceuticals to Present Preclinical Data on ARO-AAT at The Liver Meeting(R) October 10th, 2017

Arrowhead to Present at Chardan Gene Therapy Conference October 3rd, 2017

'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice October 3rd, 2017

Nanoelectronics

Nanometrics Announces Preliminary Results for the Third Quarter of 2017: Quarterly Results Impacted by Delays in Revenue Recognition on Multiple Systems into Japan October 12th, 2017

Seeing the next dimension of computer chips: Researchers image perfectly smooth side-surfaces of 3-D silicon crystals with a scanning tunneling microscope, paving the way for smaller and faster computing devices October 11th, 2017

Columbia engineers invent breakthrough millimeter-wave circulator IC October 6th, 2017

Tungsten offers nano-interconnects a path of least resistance: Crystalline tungsten shows insight and promise in addressing the challenges of electrical interconnects that have high resistivity at the nanoscale October 4th, 2017

Announcements

Novel 'converter' heralds breakthrough in ultra-fast data processing at nanoscale: Invention bagged four patents and could potentially make microprocessor chips work 1,000 times faster October 20th, 2017

Strange but true: turning a material upside down can sometimes make it softer October 20th, 2017

Leti Coordinating Project to Develop Innovative Drivetrains for 3rd-generation Electric Vehicles: CEA Techís Contribution Includes Litenís Knowhow in Magnetic Materials and Simulation And Letiís Expertise in Wide-bandgap Semiconductors October 20th, 2017

MIPT scientists revisit optical constants of ultrathin gold films October 20th, 2017

Nanobiotechnology

Spinning strands hint at folding dynamics: Rice University lab uses magnetic beads to model microscopic proteins, polymers October 17th, 2017

Arrowhead Pharmaceuticals to Present Preclinical Data on ARO-AAT at The Liver Meeting(R) October 10th, 2017

Arrowhead to Present at Chardan Gene Therapy Conference October 3rd, 2017

'CRISPR-Gold' fixes Duchenne muscular dystrophy mutation in mice October 3rd, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project