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Home > News > Des affections pulmonaires chez des souris

November 27th, 2009

Des affections pulmonaires chez des souris

Abstract:
Les nanotubes de carbone sont, de toutes les nanoparticules, celles qui ont fait l'objet du plus grand nombre de publications scientifiques. Même si les données toxicologiques restent très parcellaires, elles invitent à la prudence.

Certaines études ont été menées in vitro. Elles mettent en évidence "le caractère insoluble des nanotubes de carbone" et leur capacité "à pénétrer à l'intérieur des cellules et provoquer une cytotoxicité", c'est-à-dire à altérer ces cellules, résume l'Institut national de recherche et de sécurité (INRS). D'autres expériences ont été réalisées in vivo, sur des souris ou des rats auxquels ont été administrées de fortes doses de nanotubes. Conclusion : "Plusieurs études démontrent clairement la biopersistance de ces nano-objets et leur capacité à engendrer une inflammation pulmonaire ainsi qu'une fibrose." Ces premiers résultats, souligne l'INRS, "suggèrent que les nanotubes de carbone seraient potentiellement toxiques pour l'homme".

Source:
lemonde.fr

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