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Home > Press > Dolomite enables experiments with nanoscale volumes: Mitos Wellplate for small-scale reagent droplets or cells

Abstract:
Dolomite, a world leader in microfluidic design and manufacture, has introduced the Mitos Wellplate for holding small reagent droplets or small groups of cells. With a 40 x 40 array of nano-litre wells, each standard plate has a well volume of 0.26 nl to enable experiments to occur using nanoscale volumes.

Dolomite enables experiments with nanoscale volumes: Mitos Wellplate for small-scale reagent droplets or cells

Royston, UK | Posted on September 17th, 2009

Covering a small area of 10 x 10 mm, the array of wells is designed to fit onto a microscope slide and under a standard coverslip. The wet etching process provides a surface roughness of <5 nm, enabling easy access for microscopy systems. Furthermore, with a depth of 2 mm, the wellplate provides excellent optical transmission for clear observation of each well.

With the ability to be etched to a range of depths or diameters, as required, each well can be customized to offer alternate volumes and two layers can be used to form more complex geometries. The surface of the chip is naturally hydrophilic; however custom coatings are available, which include a hydrophobic, gold or platinum layer that can be applied to the surface of the well.

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About Dolomite
Dolomite is a global leader in the design and manufacture of microfluidics devices. With offices in the UK, US and Japan and distributors throughout the rest of the world, its clients range from universities developing leading-edge analytical equipment, to manufacturers of chemical, life sciences and clinical diagnostics systems.



Excellent microfabrication facilities that include cleanrooms, precision glass processing facilities and applications laboratories were established with £2m in funding from the UK Department of Trade and Industry's Micro and Nano Technology (MNT) Manufacturing Initiative. Dolomite’s expertise includes top quality engineering and scientific staff with strong backgrounds across the broad range of disciplines required for success in bringing microfluidics applications to the market, including chemistry, biotechnology, control system development, electronics, physics and instrument design and supply.

For more information, please click here

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Dolomite
Mike Hawes
+44 1763 242491


Tim Landucci
+44 1763 242491


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Carolyn Butchers
+44 (0)1489 557672

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