Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Using carbon nanotubes to detect nitric oxide: New sensor could reveal nitric oxide's role in living cells

Abstract:
Source: "The rational design of nitric oxide selectivity in single-walled carbon nanotube near infrared fluorescence sensors for biological detection"
Jong-Ho Kim et al
Nature Chemistry

Using carbon nanotubes to detect nitric oxide: New sensor could reveal nitric oxide's role in living cells

Cambridge, MA | Posted on August 23rd, 2009

Results: A new carbon nanotube sensor developed at MIT is the first sensor that can reversibly detect nitric oxide, a gas that cells commonly use to communicate with each other. Because the nitric oxide-carbon nanotube binding is reversible, the sensor can be used multiple times.

Why it matters: Nitric oxide is notoriously difficult to detect because it is so unstable. Monitoring nitric oxide levels in living cells, in real time, could help researchers figure out its role in cancer and other diseases. It would also allow closer study of nitric-oxide-releasing cancer drugs now in clinical trials. Biologists could also use such sensors to study nitric oxide's effects on the brain, where it acts as a neurotransmitter. Michael Strano, associate professor of chemical engineering and leader of the research team, says the advance will enable scientists to begin to answer some fundamental, long-standing biological questions.

How they did it: The researchers coated carbon nanotubes with a polymer designed to specifically attract nitric oxide. The polymer is wrapped tightly enough that only small molecules can get through to bind the nanotube, and the nitric oxide is strongly attracted to the nanotube by an extra pair of electrons passed from the polymer to the nanotube. The sensor is activated by near-infrared light, which easily penetrates the human body (biological tissues are relatively transparent to this kind of light).

Next steps: The team plans to start testing the sensors in living animals, and is working on similar sensors that can detect molecules other than nitric oxide.

####

About MIT
The mission of MIT is to advance knowledge and educate students in science, technology, and other areas of scholarship that will best serve the nation and the world in the 21st century.

For more information, please click here

Contacts:
news office
room 11-400 77 massachusetts avenue
cambridge, ma 02139-4307 617-253-2700

Copyright © MIT

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Using magnetic fields to understand high-temperature superconductivity: Los Alamos explores experimental path to potential 'next theory of superconductivity' March 27th, 2015

Nanotubes/Buckyballs

Carbon nanotube fibers make superior links to brain: Rice University invention provides two-way communication with neurons March 25th, 2015

Iranian Scientists Eliminate Expensive Materials from Diabetes Diagnosis Sensors March 25th, 2015

Effect of Carbon Nanotubes on Properties of Cement Composites Studied in Iran March 23rd, 2015

First proof of isolated attosecond pulse generation at the carbon K-edge March 20th, 2015

Sensors

UW scientists build a nanolaser using a single atomic sheet March 24th, 2015

Iranian Researchers Present Model to Determine Dynamic Behavior of Nanostructures March 24th, 2015

Nanodevice Invented in Iran to Detect Hydrogen Sulfide in Oil, Gas Industry March 20th, 2015

LamdaGen Corporation Launches Taiwan Diagnostic Subsidiary March 19th, 2015

Discoveries

Chemists make new silicon-based nanomaterials March 27th, 2015

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Announcements

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Using magnetic fields to understand high-temperature superconductivity: Los Alamos explores experimental path to potential 'next theory of superconductivity' March 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE