Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Using carbon nanotubes to detect nitric oxide: New sensor could reveal nitric oxide's role in living cells

Abstract:
Source: "The rational design of nitric oxide selectivity in single-walled carbon nanotube near infrared fluorescence sensors for biological detection"
Jong-Ho Kim et al
Nature Chemistry

Using carbon nanotubes to detect nitric oxide: New sensor could reveal nitric oxide's role in living cells

Cambridge, MA | Posted on August 23rd, 2009

Results: A new carbon nanotube sensor developed at MIT is the first sensor that can reversibly detect nitric oxide, a gas that cells commonly use to communicate with each other. Because the nitric oxide-carbon nanotube binding is reversible, the sensor can be used multiple times.

Why it matters: Nitric oxide is notoriously difficult to detect because it is so unstable. Monitoring nitric oxide levels in living cells, in real time, could help researchers figure out its role in cancer and other diseases. It would also allow closer study of nitric-oxide-releasing cancer drugs now in clinical trials. Biologists could also use such sensors to study nitric oxide's effects on the brain, where it acts as a neurotransmitter. Michael Strano, associate professor of chemical engineering and leader of the research team, says the advance will enable scientists to begin to answer some fundamental, long-standing biological questions.

How they did it: The researchers coated carbon nanotubes with a polymer designed to specifically attract nitric oxide. The polymer is wrapped tightly enough that only small molecules can get through to bind the nanotube, and the nitric oxide is strongly attracted to the nanotube by an extra pair of electrons passed from the polymer to the nanotube. The sensor is activated by near-infrared light, which easily penetrates the human body (biological tissues are relatively transparent to this kind of light).

Next steps: The team plans to start testing the sensors in living animals, and is working on similar sensors that can detect molecules other than nitric oxide.

####

About MIT
The mission of MIT is to advance knowledge and educate students in science, technology, and other areas of scholarship that will best serve the nation and the world in the 21st century.

For more information, please click here

Contacts:
news office
room 11-400 77 massachusetts avenue
cambridge, ma 02139-4307 617-253-2700

Copyright © MIT

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

GLOBALFOUNDRIES to Expand Presence in China with 300mm Fab in Chongqing: Company plans new manufacturing facility and additional design capabilities to serve customers in China May 31st, 2016

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

UK NANOSAFETY GROUP publishes 2nd Edition of guidance to support safe working with nanomaterials May 30th, 2016

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Nanotubes/Buckyballs/Fullerenes

Programmable materials find strength in molecular repetition May 23rd, 2016

Nanotubes are beacons in cancer-imaging technique: Rice University researchers use spectral triangulation to pinpoint location of tumors May 21st, 2016

Unveiling the electron's motion in a carbon nanocoil: Development of a precise resistivity measurement system for quasi-one-dimensional nanomaterials using a focused ion beam May 16th, 2016

New research shows how silver could be the key to gold-standard flexible gadgets: Silver nanowires are an ideal material for current and future flexible touch-screen technologies May 13th, 2016

Sensors

The next generation of carbon monoxide nanosensors May 26th, 2016

Dartmouth team creates new method to control quantum systems May 24th, 2016

Electronic device detects molecules linked to cancer, Alzheimer's and Parkinson's: An inexpensive portable biosensor has been developed by researchers at Brazil's National Nanotechnology Laboratory with FAPESP's support May 20th, 2016

Making organs transparent to improve nanomedicine (video) May 13th, 2016

Discoveries

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

Automating DNA origami opens door to many new uses: Like 3-D printing did for larger objects, method makes it easy to build nanoparticles out of DNA May 30th, 2016

Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016

Scientists illuminate a hidden regulator in gene transcription: New super-resolution technique visualizes important role of short-lived enzyme clusters May 27th, 2016

Announcements

GLOBALFOUNDRIES to Expand Presence in China with 300mm Fab in Chongqing: Company plans new manufacturing facility and additional design capabilities to serve customers in China May 31st, 2016

Nanobiotix establishes promising preclinical proof-of-concept in Immuno Oncology May 31st, 2016

UK NANOSAFETY GROUP publishes 2nd Edition of guidance to support safe working with nanomaterials May 30th, 2016

Fast, stretchy circuits could yield new wave of wearable electronics May 30th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic