Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Using carbon nanotubes to detect nitric oxide: New sensor could reveal nitric oxide's role in living cells

Abstract:
Source: "The rational design of nitric oxide selectivity in single-walled carbon nanotube near infrared fluorescence sensors for biological detection"
Jong-Ho Kim et al
Nature Chemistry

Using carbon nanotubes to detect nitric oxide: New sensor could reveal nitric oxide's role in living cells

Cambridge, MA | Posted on August 23rd, 2009

Results: A new carbon nanotube sensor developed at MIT is the first sensor that can reversibly detect nitric oxide, a gas that cells commonly use to communicate with each other. Because the nitric oxide-carbon nanotube binding is reversible, the sensor can be used multiple times.

Why it matters: Nitric oxide is notoriously difficult to detect because it is so unstable. Monitoring nitric oxide levels in living cells, in real time, could help researchers figure out its role in cancer and other diseases. It would also allow closer study of nitric-oxide-releasing cancer drugs now in clinical trials. Biologists could also use such sensors to study nitric oxide's effects on the brain, where it acts as a neurotransmitter. Michael Strano, associate professor of chemical engineering and leader of the research team, says the advance will enable scientists to begin to answer some fundamental, long-standing biological questions.

How they did it: The researchers coated carbon nanotubes with a polymer designed to specifically attract nitric oxide. The polymer is wrapped tightly enough that only small molecules can get through to bind the nanotube, and the nitric oxide is strongly attracted to the nanotube by an extra pair of electrons passed from the polymer to the nanotube. The sensor is activated by near-infrared light, which easily penetrates the human body (biological tissues are relatively transparent to this kind of light).

Next steps: The team plans to start testing the sensors in living animals, and is working on similar sensors that can detect molecules other than nitric oxide.

####

About MIT
The mission of MIT is to advance knowledge and educate students in science, technology, and other areas of scholarship that will best serve the nation and the world in the 21st century.

For more information, please click here

Contacts:
news office
room 11-400 77 massachusetts avenue
cambridge, ma 02139-4307 617-253-2700

Copyright © MIT

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Atom-thick CCD could capture images: Rice University scientists develop two-dimensional, light-sensitive material December 20th, 2014

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Aculon Hires New Business Development Director December 19th, 2014

Nanotubes/Buckyballs

A sponge-like molecular cage for purification of fullerenes December 15th, 2014

'Trojan horse' proteins used to target hard-to-reach cancers: Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without causing the damaging side effects the treatment normally brings December 11th, 2014

Detecting gases wirelessly and cheaply: New sensor can transmit information on hazardous chemicals or food spoilage to a smartphone December 8th, 2014

Green meets nano: Scientists at TU Darmstadt create multifunctional nanotubes using nontoxic materials December 3rd, 2014

Sensors

Promising new method for rapidly screening cancer drugs: UMass Amherst researchers invent fast, accurate new nanoparticle-based sensor system December 15th, 2014

Graphene Applied in Production of Recyclable Electrodes December 13th, 2014

Detecting gases wirelessly and cheaply: New sensor can transmit information on hazardous chemicals or food spoilage to a smartphone December 8th, 2014

Nanosensor to Detect Naproxen Drug Produced in Iran December 6th, 2014

Discoveries

Atom-thick CCD could capture images: Rice University scientists develop two-dimensional, light-sensitive material December 20th, 2014

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Iranian Scientists Use Nanotechnology to Increase Power, Energy of Supercapacitors December 18th, 2014

Announcements

Atom-thick CCD could capture images: Rice University scientists develop two-dimensional, light-sensitive material December 20th, 2014

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Aculon Hires New Business Development Director December 19th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE