- About Us
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
Source: "The rational design of nitric oxide selectivity in single-walled carbon nanotube near infrared fluorescence sensors for biological detection"
Jong-Ho Kim et al
Results: A new carbon nanotube sensor developed at MIT is the first sensor that can reversibly detect nitric oxide, a gas that cells commonly use to communicate with each other. Because the nitric oxide-carbon nanotube binding is reversible, the sensor can be used multiple times.
Why it matters: Nitric oxide is notoriously difficult to detect because it is so unstable. Monitoring nitric oxide levels in living cells, in real time, could help researchers figure out its role in cancer and other diseases. It would also allow closer study of nitric-oxide-releasing cancer drugs now in clinical trials. Biologists could also use such sensors to study nitric oxide's effects on the brain, where it acts as a neurotransmitter. Michael Strano, associate professor of chemical engineering and leader of the research team, says the advance will enable scientists to begin to answer some fundamental, long-standing biological questions.
How they did it: The researchers coated carbon nanotubes with a polymer designed to specifically attract nitric oxide. The polymer is wrapped tightly enough that only small molecules can get through to bind the nanotube, and the nitric oxide is strongly attracted to the nanotube by an extra pair of electrons passed from the polymer to the nanotube. The sensor is activated by near-infrared light, which easily penetrates the human body (biological tissues are relatively transparent to this kind of light).
Next steps: The team plans to start testing the sensors in living animals, and is working on similar sensors that can detect molecules other than nitric oxide.
The mission of MIT is to advance knowledge and educate students in science, technology, and other areas of scholarship that will best serve the nation and the world in the 21st century.
For more information, please click here
room 11-400 77 massachusetts avenue
cambridge, ma 02139-4307 617-253-2700
Copyright © MITIf you have a comment, please Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
|Related News Press|
News and information
Programmable materials find strength in molecular repetition May 23rd, 2016
The next generation of carbon monoxide nanosensors May 26th, 2016
Dartmouth team creates new method to control quantum systems May 24th, 2016
Electronic device detects molecules linked to cancer, Alzheimer's and Parkinson's: An inexpensive portable biosensor has been developed by researchers at Brazil's National Nanotechnology Laboratory with FAPESP's support May 20th, 2016
Making organs transparent to improve nanomedicine (video) May 13th, 2016
Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016