Nanotechnology Now

• About Us
  
  • Advertising
  • Our Mission
  • Our Team
  • Comments
  • Friends
  • Contact
• Nanotechnology
• News
  
  • Current News
  • Press Releases
  • Submit Press
  • Press kit
  • Interviews
• Columns
• Products
  
  • Our Products
  • Books
  • Featured Books
• Directories
  
  • Companies/Academic
  • Events
  • Glossary
  • Best Of
• Career Center
• Nano-Social Network
• Nano Consulting
• My Account

Home > News > PALM microscopy enables understanding of cell organization's impact on biological function

July 14th, 2009

PALM microscopy enables understanding of cell organization's impact on biological function

Abstract:
Using PALM, Liphardt and his colleagues mapped the cellular locations of three proteins central to the chemotaxis signaling network--Tar, CheY and CheW--with a mean precision of 15 nanometers. They found that cluster sizes were distributed with no one size being "characteristic." For example, a third of the Tar proteins were part of smaller lateral clusters and not of the large polar clusters. Analysis of the relative cellular locations of more than one million individual proteins from 326 cells determined that they are not actively distributed or attached to specific locations in cells, as had been hypothesized.
"Instead," said Liphardt, "random lateral protein diffusion and protein-protein interactions are probably sufficient to generate the observed complex, ordered patterns. This simple stochastic self-assembly mechanism, which can create and maintain periodic structures in biological membranes without direct cytoskeletal involvement or active transport, may prove to be widespread in both prokaryotic and eukaryotic cells."

Source:
bioopticsworld.com

Bookmark:

Related News Press

News and information

Less is More: Novel Cellulose Structure Requires Fewer Enzymes to Process Biomass to Fuel June 19th, 2013

Sound waves precisely position nanowires June 19th, 2013

Scientists Use Nanotechnology to Increase Thermal Stability of Essential Oils June 19th, 2013

Production of Bioactive Material for Quick Treatment of Bone Damages June 19th, 2013

Nanomedicine

Production of Bioactive Material for Quick Treatment of Bone Damages June 19th, 2013

3-D printing could lead to tiny medical implants, electronics, robots, more June 18th, 2013

Pioneering breakthrough of chemical nanoengineering to design drugs controlled by light June 18th, 2013

Study Shows How the Nanog Protein Promotes Growth of Head and Neck Cancer June 18th, 2013

Announcements

Less is More: Novel Cellulose Structure Requires Fewer Enzymes to Process Biomass to Fuel June 19th, 2013

Sound waves precisely position nanowires June 19th, 2013

Scientists Use Nanotechnology to Increase Thermal Stability of Essential Oils June 19th, 2013

Production of Bioactive Material for Quick Treatment of Bone Damages June 19th, 2013

Tools

Beating the Diffraction Limit by 1000X – An introduction to nanoscale IR imaging on Bruker AFMs with applications in graphene June 19th, 2013

Nanometrics Announces Participation in 5th Annual CEO Investor Summit: Accredited Investor and Publishing Research Analyst Event to be Held Concurrently With SEMICON West and Intersolar 2013 in San Francisco June 19th, 2013

Beneq’s comprehensive industrial Thin Film Coating Services shorten time to market June 18th, 2013

Which qubit my dear? New method to distinguish between neighbouring quantum bits June 18th, 2013

Nanobiotechnology

Iranian Scientists Produce Dynamometer for Nanoparticles, Biocells June 15th, 2013

Shape of nanoparticles points the way toward more targeted drugs: A collaboration of scientists at Sanford-Burnham and the University of California, Santa Barbara, finds that rod-shaped particles, rather than spherical particles, appear more effective at adhering to cells June 10th, 2013

Catching individual molecules in a million with optical antennas inside nano-boxes June 10th, 2013

Whispering light hears liquids talk: University of Illinois researchers build first-ever bridge between optomechanics and microfluidics June 7th, 2013