Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Keio University’s Dr. Suda Selects Fluidigm BioMark™ System for Single Stem Cell Research: Single Cell Study Holds the Key to Hematopoietic Stem Cell Progress

Abstract:
Fluidigm Corporation today announced that Dr. Toshio Suda of Keio University's 21st Century Center of Excellence (COE) Program, Graduate School of Medicine, has selected the BioMark™ System for Genetic Analysis to assist their research of mouse hematopoietic single stem cells.

Keio University’s Dr. Suda Selects Fluidigm BioMark™ System for Single Stem Cell Research: Single Cell Study Holds the Key to Hematopoietic Stem Cell Progress

SOUTH SAN FRANCISCO, CA | Posted on June 23rd, 2009

Keio University's COE is using the unique microfluidic properties of the Fluidigm's integrated fluidic circuits (IFCs) to analyze selected genes in hematopoietic stem cells (HSCs). The interaction of HSCs with their particular microenvironment, known as the stem cell niche, is critical for adult hematopoiesis in bone marrow. The COE plans to use both Fluidigm's Dynamic Array™ and Digital Array™ IFCs in this effort.

Keio University's COE Graduate School of Medicine Program brings together researchers and clinicians from stem cell biology, regenerative medicine, immunology, autoimmune disease and infectious disease areas to form a scientific community that conducts basic medical research, utilizing the elucidation of the pathology of intractable diseases and unique disease model systems to develop new methods of treatment.

"Dr. Suda's work in modeling the differentiation of stem cells and purification methods for hematopoietic stem cells is remarkable. We hope Fluidigm's technology and its ability to provide extreme sensitivity at the single-cell level can help him unlock new vistas of understanding as Dr. Suda explores hematopoietic stem cells and their niches," said Gajus Worthington, president and chief executive officer of Fluidigm.

"Our research in hematopoietic stem cells and how they interact with their niches to maintain a balance between self-renewal and differentiation is key to ultimately establishing techniques for niche-based therapy. The Fluidigm BioMark technology enables us to easily study populations of HSCs on the single cell level allowing us to accurately characterize the cellular and molecular components of ‘Niche complex'," said Dr. Suda.

The ability of Fluidigm's microfluidic devices - called integrated fluidic circuits (IFCs) -- to isolate and control individual molecules provides great insight into the development of biological events that influence stem cell differentiation. Analyzing the stochastic differences between individual cells typically requires studying large numbers of individual cells and genes. Fluidigm's IFC volume requirements are so low that researchers have been able to study as many as 1,000 genes from an individual cell. The technology facilitates thousands of single cell experiments allowing the biological differences to manifest themselves.

A recent Nature Reports Stem Cells article noted: "Stem cells are defined by their remarkable ability to self-renew and differentiate into specialized cells. But even after careful sorting, a single population of stem cells is dynamic: some divide rapidly and others more slowly; some differentiate, others self-renew; some can give rise to more lineages than others. Because of this variation, population studies of stem cells are unable to accurately address essential questions, such as defining discrete steps from a single stem cell to a complex population of cells."

"Each stem cell needs to be treated as an individual because it's not necessarily in the same state at every point in time. You have to look at them as individuals," noted Worthington.

The complete Nature article is available at: www.nature.com/stemcells/2009/0905/090507/full/stemcells.2009.71.html

####

About Fluidigm Corporation
Fluidigm develops, manufactures and markets proprietary Integrated Fluidic Circuit (IFC) systems that significantly improve productivity in life science research. Fluidigm’s IFCs enable the simultaneous performance of thousands of sophisticated biochemical measurements in extremely minute volumes. These “integrated circuits for biology” are made possible by miniaturizing and integrating liquid handling components on a single microfabricated microfluidic device. Fluidigm’s IFC systems, consisting of instrumentation, software and single-use IFCs, increase throughput, decrease costs and enhance sensitivity compared to conventional laboratory systems. Fluidigm products have not been cleared or approved by the Food and Drug Administration for use as a diagnostic and are only available for research use.

Fluidigm, the Fluidigm logo, Topaz, BioMark, Dynamic Array, Digital Array, Access Array and NanoFlex are trademarks of Fluidigm Corporation.

For more information, please click here

Contacts:
Fluidigm Corp.
Howard High
650-266-6081 (office)
510-786-7378 (mobile)

Copyright © Business Wire 2009

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

New, better way to build circuits for world's first useful quantum computers June 28th, 2016

Yale researchers’ technology turns wasted heat into power June 27th, 2016

FEI Launches Helios G4 DualBeam Series for Materials Science: The Helios G4 DualBeam Series features new capabilities to enable scientists and engineers to answer the most demanding and challenging scientific questions June 27th, 2016

Nanomedicine

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Self-assembling icosahedral protein designed: Self-assembling icosahedral protein designed June 22nd, 2016

Announcements

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

New, better way to build circuits for world's first useful quantum computers June 28th, 2016

Yale researchers’ technology turns wasted heat into power June 27th, 2016

FEI Launches Helios G4 DualBeam Series for Materials Science: The Helios G4 DualBeam Series features new capabilities to enable scientists and engineers to answer the most demanding and challenging scientific questions June 27th, 2016

Tools

FEI Launches Helios G4 DualBeam Series for Materials Science: The Helios G4 DualBeam Series features new capabilities to enable scientists and engineers to answer the most demanding and challenging scientific questions June 27th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Researchers discover new chemical sensing technique: Technique allows sharper detail -- and more information -- with near infrared light June 24th, 2016

New-Contracts/Sales/Customers

Nanometrics Selected for Third-Generation 3D-NAND Process Control: Atlas® Systems Extend Advanced Device Manufacturing Capability June 14th, 2016

Industrial Nanotech, Inc. Signs Agreement With and Receives First Purchase Order from Major New Customer in China June 6th, 2016

Deep Space Industries and SFL selected to provide satellites for HawkEye 360’s Pathfinder mission: The privately-funded space-based global wireless signal monitoring system will be developed by Deep Space Industries and UTIAS Space Flight Laboratory May 26th, 2016

Nanometrics Achieves Record 3D-NAND Bookings Quarter: A Record 3D-NAND Bookings Quarter, both in Aggregate and for Each of Three Key Customers March 28th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic