Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nanotechnology for Stent Coating Promises Improved Post-op Performance

Abstract:
A nanomatrix for stent coating designed at the University of Alabama at Birmingham (UAB) mimics natural endothelium, the substance that lines blood vessels, and promises the potential to prevent post-operative tissue scaring along the blood vessel wall, greatly reducing the possibility of future thrombosis, or blockage at the stent site. This next generation nanotechnology could prove vital to reducing coronary artery disease, the number one cause of death in the United States, said Ho-Wook Jun, Ph.D., a UAB assistant professor of Biomedical Engineering and principal investigator on the discovery.

Nanotechnology for Stent Coating Promises Improved Post-op Performance

Birmingham, AL | Posted on November 11th, 2008

Jun presented his findings Nov. 10 at the news conference on "Hi-Tech for the Heart" at the American Heart Association (AHA) Scientific Sessions 2008. He was one of three researchers selected to present at the news conference, a part of the annual AHA event this week in New Orleans that was expected to draw 20,000 attendees.

Jun and his team spent the past 18 months developing the coating technology, a biomimetic nanomatrix, or a synthetic system on a nanoscopic level, that can be applied to the drug-eluting stents implanted in 6 million patients worldwide over the last three years to open clogged blood vessels and prevent heart attack. The research was funded by a two-year, $240,000 Early Career Award grant from the Wallace H. Coulter Foundation.

"Blood vessels cannot recover full function with existing stents, but our coating could allow for a full recovery of the blood vessel," Jun said. "This will increase the long-term success of stents, especially for the elderly who are more at risk for a secondary episode at the stent insertion point."

Jun and his team's work is part of UAB's interdisciplinary approach to research, he said. Jun's co-principal investigator, Brigitta Brott, M.D., along with collaborators Jack Lancaster, Ph.D., and Peter Anderson, Ph.D., all from the School of Medicine, have contributed valuable medical and health-based knowledge to the nanomatrix's research and design.

Jun has submitted a patent for this revolutionary biomedical technology, and animal testing of the stent coating could begin by the first of the year. Jun believes the coating could be applied to a range of cardiovascular devices beyond stents, including vascular grafts or prosthetic heart valves, to improve overall cardio health.

"This technology has great potential for the future, and to be featured as a new frontier at the national AHA conference is a great honor," Jun said.

PLEASE NOTE: Dr. Jun is a faculty member at the University of Alabama at Birmingham. UAB is ranked 27th nationally in federal research funding, attracting more than $400 million annually. The November issue of the Scientist magazine ranked UAB fifth in its Best Place to Work in Academia survey. UAB is often confused with the University of Alabama, which is a completely separate university. Please use our full name on first reference and UAB thereafter. - Thank you.

####

About University of Alabama at Birmingham
Since opening its doors in 1969, The University of Alabama at Birmingham (UAB) has used its entrepreneurial spirit to rapidly evolve from a small extension center into a comprehensive research university that encompasses 82 city blocks. What once was a commuter school for just over 5,000 students is now home to more than 17,000 students, of whom nearly 11,000 are undergraduates.

UAB’s incoming student body reflects steadily increasing preparedness. The average ACT score of entering freshmen has risen to 24. At the same time, UAB maintains its legacy as a university of opportunity. More than 30 percent of undergraduates are African-American and more than 35 percent are minorities; nearly 61 percent are females. The Princeton University Review described UAB as “a mecca of multiculturism. Here you will find students of all ages, from all walks of life, all religion and all ethnic backgrounds.” These students come from every region of the country and more than 110 nations throughout the world.

For more information, please click here

Contacts:
Andrew Hayenga
(205) 934-1676

Copyright © Newswise

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

Videos/Movies

Tiny particles could help verify goods: Chemical engineers hope smartphone-readable microparticles could crack down on counterfeiting April 15th, 2014

Biologists Develop Nanosensors to Visualize Movements and Distribution of Plant Stress Hormone April 15th, 2014

Director Wally Pfister joins UC Berkeley neuroengineers to discuss the science behind ‘Transcendence’ April 7th, 2014

KEEP CALM and PUBLISH PAPERS – a new video blog with graphic tutorials to scientific publishing April 7th, 2014

Nanomedicine

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

High-temperature plasmonics eyed for solar, computer innovation April 17th, 2014

Discoveries

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

'Exotic' material is like a switch when super thin April 18th, 2014

Announcements

MRI, on a molecular scale: Researchers develop system that could one day peer into the atomic structure of individual molecules April 20th, 2014

Iranian Researchers Present New Model to Strengthen Superconductivity at Higher Temperatures April 19th, 2014

Iranian Researchers Produce New Anti-Cancer Drug from Turmeric April 19th, 2014

Innovative strategy to facilitate organ repair April 18th, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE