Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Nanocopoeia Licenses New Polymer-Based Biomaterials Platform From the University of Western Ontario

Abstract:
Following the launch at BIO International in San Diego last week of NanoInterventions, their cardiovascular joint venture partnership, Nanocopoeia and WORLDiscoveries(TM) are pleased to announce their broader agreement to co-develop the biomedical uses of arborescent polyisobutylene-based block copolymers. Nanocopoeia, a drug delivery company specializing in therapeutic coatings for medical devices, will lead the development effort and WORLDiscoveries(TM) will participate as a partner in the market-targeted applications. The agreement includes an exclusive world-wide license, for all biomedical fields of use, for the polymer system that is the subject of US Patent No. 6,747,098 (2004) and nine other international issued patents.

Nanocopoeia Licenses New Polymer-Based Biomaterials Platform From the University of Western Ontario

ST. PAUL, MN and LONDON, ON, Canada | Posted on June 26th, 2008

Arborescent polyisobutylene-based block copolymers are branched polymers with unique properties for biomedical use. A major market opportunity is their use as a drug-eluting coating for medical devices such as coronary stents. When applied using Nanocopoeia's proprietary ElectroNanospray(TM) process, the polymer provides a highly controllable matrix for drug delivery and has excellent physical properties. For other applications, such as tissue implants, this family of polymers has many attributes in common with silicone materials but without the need of the additional chemicals that are required to formulate silicone-based devices.

Judit E. Puskas, PhD, P.Eng, led the team at Western that invented the family of polymers based on arborescent polyisobutylene. She held the Bayer/NSERC (Natural Science and Engineering Research Council of Canada) Industrial Research Chair at Western between 1998 and 2003, and is now Professor of Polymer Science at The University of Akron in Ohio. Dr. Puskas commented, "This polymer system has enormous flexibility in the way it can be applied, while remaining totally stable. That, together with the favorable biocompatibility profile of its building blocks, makes it an ideal interface with body tissues." Dr. Puskas will participate in the joint development program.

Nanocopoeia's drug delivery and coating technology uses the proprietary ElectroNanospray(TM) process to apply nanoparticle-based coatings. The unique process, which originated at the University of Minnesota, generates nanoparticles made of drugs and polymers and assembles them into films with controllable delivery.

The National Science Foundation's research funding has played an important role in launching the collaboration. The commercial development of Nanocopoeia's ElectroNanospray(TM) technology for biomedical applications has been supported through multiple SBIR Phase II and supplemental awards from the NSF Division of Industrial Innovation and Partnerships. In the course of that research, the Company's search for novel coating polymer systems led them to Dr. Puskas, resulting in the ongoing productive collaboration. Dr. Puskas' research is supported by the NSF Division of Materials Research.

Nanocopoeia's CEO, Robert A. Hoerr, MD, PhD, said, "Based on our success in working with this polymer system, we believe it will have applicability for a broad range of biomedical uses." He further commented that a first use of the polymer has been as a prototype drug-eluting stent coating based on arborescent polyisobutylene-block-polystyrene (abbreviated arbIBS) used by the joint venture NanoInterventions for its Mouse Stent Model. He continued, "Given the strong interest that NanoInterventions' Mouse Stent Model generated at BIO, we believe the polymer will be a key element in helping us to define next generation of stent-delivered therapies."

NanoInterventions is a joint venture partnership that is launching the first rapid screening model for new coronary stent coatings, using a genetically modified mouse strain with human-like atherosclerosis, a mini- stent, and experimental coatings on the stent. Joint venture partners other than Nanocopoeia and Western include Stentome, LLC, an interventional cardiology company based in Palo Alto, CA, Oxford, UK, and Galway, Ireland, and The Integra Group, a medical research organization based in Brooklyn Park, MN, that provides a full range of preclinical and clinical development services. NanoInterventions was a featured company in the Positively Minnesota pavilion in the BIO International exhibition hall, from June 17-20, 2008.

With annual research expenditures of more than $223 million and an international reputation for success, The University of Western Ontario ranks as one of the top ten research-intensive universities in Canada. Offering Canada's best student experience among its peers, Western and its affiliated research institutes provide a culture that encourages entrepreneurial research and innovation.

WORLDiscoveries(TM) is a joint venture between Lawson Health Research Institute and The University of Western Ontario, including Robarts Research Institute, that capitalizes on the institutions' combined research strengths related to medical and health-related sciences, energy and the environment and new materials. The London region is recognized as a national leader in these key areas, and the city has identified them as opportunities for further growth.

Rob Herold, Associate Director of Western's Industrial Liaison Office, commented, "The innovative structure of our licensing partnership with Nanocopoeia lets us participate in the evolving healthcare applications of this polymer platform. WORLDiscoveries(TM) was structured to enable us work with highly entrepreneurial companies like Nanocopoeia and share in their upside potential, in addition to the standard licensing process that we have traditionally used. We have great confidence both in the technology and in our new partner."

####

For more information, please click here

Copyright © PR Newswire Association LLC.

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Harris & Harris Group Portfolio Company, HZO, Announces Partnerships with Dell and Motorola August 1st, 2015

Advances and Applications in Biosensing, Sensor Power, and Sensor R&D to be Covered at Sensors Global Summit August 1st, 2015

Kalam: versatility personified August 1st, 2015

Academic/Education

Pakistani Students Who Survived Terror Attack to Attend Weeklong “NanoDiscovery Institute” at SUNY Poly CNSE in Albany July 29th, 2015

Deben reports on the use of their CT500 in the X-ray microtomography laboratory at La Trobe University, Melbourne, Australia July 22nd, 2015

JPK reports on the use of SPM in the Messersmith Group at UC Berkeley looking at biologically inspired polymer adhesives. July 21st, 2015

Renishaw adds Raman analysis to Scanning Electron Microscopy at the University of Sydney, Australia July 9th, 2015

Nanomedicine

Gold-diamond nanodevice for hyperlocalised cancer therapy: Gold nanorods can be used as remote controlled nanoheaters delivering the right amount of thermal treatment to cancer cells, thanks to diamond nanocrystals used as temperature sensors August 1st, 2015

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

Take a trip through the brain July 30th, 2015

Sol-gel capacitor dielectric offers record-high energy storage July 30th, 2015

Materials/Metamaterials

Shaping the hilly landscapes of a semi-conductor nanoworld August 1st, 2015

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Harris & Harris Group Portfolio Company, HZO, Announces Partnerships with Dell and Motorola August 1st, 2015

Announcements

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Harris & Harris Group Portfolio Company, HZO, Announces Partnerships with Dell and Motorola August 1st, 2015

Advances and Applications in Biosensing, Sensor Power, and Sensor R&D to be Covered at Sensors Global Summit August 1st, 2015

Patents/IP/Tech Transfer/Licensing

Quantum networks: Back and forth are not equal distances! July 28th, 2015

Reshaping the solar spectrum to turn light to electricity: UC Riverside researchers find a way to use the infrared region of the sun's spectrum to make solar cells more efficient July 27th, 2015

Smarter window materials can control light and energy July 22nd, 2015

Magnetic nanoparticles could be key to effective immunotherapy: New method moves promising strategy closer to clinical use July 15th, 2015

Nanobiotechnology

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

European Technology Platform for Nanomedicine and ENATRANS European Consortium Launch the 2nd edition of the Nanomedicine Award: The Award to be presented at BIO-Europe conference in Munich, November 2015 July 30th, 2015

New computer model could explain how simple molecules took first step toward life: Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules July 28th, 2015

Spintronics: Molecules stabilizing magnetism: Organic molecules fixing the magnetic orientation of a cobalt surface/ building block for a compact and low-cost storage technology/ publication in Nature Materials July 25th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project