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Home > News > Medical nanoimaging pinpoints cause of cataracts

October 15th, 2007

Medical nanoimaging pinpoints cause of cataracts

Abstract:
At the Institut Curie, Simon Scheuring, beneficiary of the Inserm Avenir program and coordinator of the CNRS/Inserm "Atomic force microscopy (AFM) of proteins in native membranes" team, has for the first time observed a diseased tissue at very high resolution using atomic force microscopy (AFM). By studying the membranes of cells in a patient's eye cataract, Scheuring has discovered the molecular cause of this disease. This is the first time that high-resolution AFM imaging of a diseased tissue has yielded information on the single molecule level of the disease. AFM has emerged from the state-of-the-art laboratory to bring us medical nanoimaging. These results are now online in the Journal of Molecular Biology ("The supramolecular architecture of junctional microdomains in native lens membranes").

Source:
nanowerk.com

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