- About Us
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
Scientists in Taiwan are reporting development of a nanoparticle drug delivery system that shows promise as a potential way to administer insulin and perhaps other protein-based drugs by mouth rather than injection or nasal sprays.
Hsing-Wen Sung and colleagues at the National Tsing Hua University, the Chinese Naval Academy and the National Health Research Institute point out that stomach acid destroys protein-based drugs, making them ineffective. That problem has led to broadly based efforts to find ways of encapsulating or otherwise protecting insulin from damage in the stomach so it could be given in a convenient oral form. Once the drug passes through the stomach, it can be absorbed in the small intestine.
In their new research, scheduled for the Jan. 8 issue of ACS' Biomacromolecules, a monthly journal, researchers describe loading insulin into nanospheres made from chitosan, a natural carbohydrate polymer material obtained commercially from shells of shrimp that is nontoxic and biocompatible. When given to diabetic laboratory rats, the insulin-loaded nanoparticles successfully reduced blood sugar levels in the animals.
JACS, founded in 1879, is the flagship journal of the American Chemical Society and the preeminent journal in the field. This periodical is devoted to the publication of research papers in all fields of chemistry and publishes approximately 17,000 pages of new chemistry a year. Published weekly, JACS provides research essential to the field of chemistry.
For more information, please click here
Hsing-Wen Sung, Ph.D.
National Tsing Hua University
Copyright © BiomacromoleculesIf you have a comment, please Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
|Related News Press|
Simple attraction: Researchers control protein release from nanoparticles without encapsulation: U of T Engineering discovery stands to improve reliability and fabrication process for treatments to conditions such as spinal cord damage and stroke May 28th, 2016
Are humans the new supercomputer?Today, people of all backgrounds can contribute to solving serious scientific problems by playing computer games. A Danish research group has extended the limits of quantum physics calculations and simultaneously blurred the boundaries between mac April 14th, 2016
UCLA nanoscientists engage shoppers in fun conversations March 8th, 2016
Risk Analysis Publishes Non-Animal Strategy to Assess Nanomaterials February 24th, 2016