Home > Press > Toward a new oral delivery system for insulin using nanoshell shields
Abstract:
Scientists in Taiwan are reporting development of a nanoparticle drug delivery system that shows promise as a potential way to administer insulin and perhaps other protein-based drugs by mouth rather than injection or nasal sprays.
Toward a new oral delivery system for insulin using nanoshell shields
Hsinchu, China | Posted on January 3rd, 2007Hsing-Wen Sung and colleagues at the National Tsing Hua University, the Chinese Naval Academy and the National Health Research Institute point out that stomach acid destroys protein-based drugs, making them ineffective. That problem has led to broadly based efforts to find ways of encapsulating or otherwise protecting insulin from damage in the stomach so it could be given in a convenient oral form. Once the drug passes through the stomach, it can be absorbed in the small intestine.
In their new research, scheduled for the Jan. 8 issue of ACS' Biomacromolecules, a monthly journal, researchers describe loading insulin into nanospheres made from chitosan, a natural carbohydrate polymer material obtained commercially from shells of shrimp that is nontoxic and biocompatible. When given to diabetic laboratory rats, the insulin-loaded nanoparticles successfully reduced blood sugar levels in the animals.
####
About Biomacromolecules
JACS, founded in 1879, is the flagship journal of the American Chemical Society and the preeminent journal in the field. This periodical is devoted to the publication of research papers in all fields of chemistry and publishes approximately 17,000 pages of new chemistry a year. Published weekly, JACS provides research essential to the field of chemistry.
For more information, please click here
Contacts:
Hsing-Wen Sung, Ph.D.
National Tsing Hua University
Hsinchu, China
Phone: 886-574-2504
Fax: 886-3-572-6832
Email:
Copyright © Biomacromolecules
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related News Press |
Nanomedicine
Researchers developed nanoparticle based contrast agent for dual modal imaging of cancer June 21st, 2017
Learning with light: New system allows optical “deep learning”: Neural networks could be implemented more quickly using new photonic technology June 12th, 2017
Mussels add muscle to biocompatible fibers: Rice University chemists develop hydrogel strings using compound found in sea creatures June 9th, 2017
Discoveries
Rice U. chemists create 3-D printed graphene foam June 22nd, 2017
Tiny bubbles provide tremendous propulsion in new microparticles research-Ben-Gurion U. June 21st, 2017
Enhanced photocatalytic activity by Cu2O nanoparticles integrated H2Ti3O7 nanotubes June 21st, 2017
Researchers developed nanoparticle based contrast agent for dual modal imaging of cancer June 21st, 2017
Announcements
Rice U. chemists create 3-D printed graphene foam June 22nd, 2017
Tiny bubbles provide tremendous propulsion in new microparticles research-Ben-Gurion U. June 21st, 2017
Enhanced photocatalytic activity by Cu2O nanoparticles integrated H2Ti3O7 nanotubes June 21st, 2017
Researchers developed nanoparticle based contrast agent for dual modal imaging of cancer June 21st, 2017
Human Interest/Art
Weizmann Institute of Science Presents: Weizmann Wonder Wander - 4G - is Online June 21st, 2016
Call for NanoArt and Art-Science-Technology Papers June 9th, 2016
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
University Technology Transfer & Patents
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||