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Quantum Dot Corporation Announces Scientific Publication Demonstrating the Detection of Breast Cancer Markers

Hayward, CA. December 2nd, 2002

Quantum Dot Corporation (QDC), the leader in Qdot(tm) biotechnology applications and products, announced today the publication of a seminal scientific paper in the prestigious journal Nature Biotechnology. The paper, entitled "Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots", was published in the on-line version of Nature Biotechnology, following collaborative work performed by scientists at Genentech and QDC. The print version will be published in January 2003.

"The promise of Qdot conjugates to revolutionize biological detection has now become a reality. Our work with Genentech is the first practical application of the Qdot technology in an important biological system - specific detection of breast cancer markers. These results demonstrate the dramatic sensitivity and stability benefits enabled using Qdot detection," said Xingyong Wu, Ph.D., senior staff scientist at QDC, and the lead author of the paper. "We have also demonstrated cancer marker detection in live cancer cells, an extremely difficult task using conventional methods," continued Dr. Wu.

"This work demonstrates how Qdot technology allows the detection of many biological analytes simultaneously, using a range of different colored Qdot nanocrystals," stated Charlie Hotz, Ph.D., director of chemistry at QDC. "This range of colors is achieved using different sized nanocrystals. Our unique ability to precisely tune the size of these nanoscale structures, at tolerances below one nanometer, is critical," continued Dr. Hotz.

"Coming so rapidly on the heels of our first product launch last month, this work is a strong validation of the commercial value of the Qdot technology," said Carol C. Lou, QDC's President and Chief Operations Officer. "We highly value the relationship with our colleagues at Genentech, and we look forward to working with them on further innovative applications of our products."

Qdot(tm) nanocrystals, or quantum dots, are nanometer sized semiconductor crystals that brightly light up specific biological events. These nano-scale molecular light emitting diodes (LEDs) allow rapid, parallel, and ultra-sensitive detection of biomolecular interactions.

Founded in 1998, Quantum Dot Corporation is located in Hayward, CA. The company and its advisors are the world's leading experts in semiconductor nanocrystal (Qdot(tm)) technology and its applications. QDC sells and markets products to life science researchers worldwide, and is seeking marketing partners for its diagnostic applications. Additional information about QDC can be found at

For further information, please contact Andy Watson at or 510-887-8775 x4106.

Reprinted with premission. Copyright Quantum Dot Corporation.

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