Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > Turning the heat on: A flexible device for localized heat treatment of living tissues

Figure 1 Induction Heating-based Flexible Device to Revolutionize Targeted Thermotherapy.

CREDIT
Tokyo Tech
Figure 1 Induction Heating-based Flexible Device to Revolutionize Targeted Thermotherapy. CREDIT Tokyo Tech

Abstract:
Thermotherapy or heat treatment can help in treating lesions and other tissue injuries. For example, chemotherapy or radiotherapy, when combined with thermotherapy, kills tumorous cells more effectively. Thermotherapy is considered a promising approach for treating internal lesions, but the advancement in the field depends on the availability of patient-friendly heat-inducing devices capable of rapidly increasing the temperature of target tissues.

Turning the heat on: A flexible device for localized heat treatment of living tissues

Tokyo, Japan | Posted on June 11th, 2021

Current clinical practices around thermotherapy majorly employ heat-generating devices that are probed inside the human body or are in contact with the skin. Receiving energy from external power sources and often operating through converging magnetic fields, these devices are usually large in size and static, limiting the movement of patients and also prolonging operational time.

An alternative option is small and flexible devices that can be implanted in the patient's body; however, such implantable devices must be flexible, body-compatible, heat resistant, and be powered wirelessly for heat generation--some of the criteria that are essential for their clinical use.

Recently, researchers at Tokyo Tech have innovated a heat-generating device that can revolutionize the field of thermotherapy by meeting all of the above criteria. Their innovation was reported in an article published in Advanced Functional Materials. Discussing their motivation, Associate Professor Toshinori Fujie, who led the study, explains ''One of the major obstacles in developing an implantable heating device is the requirement of incorporating electronic elements such capacitors in the circuit of the device itself. Such insertion takes away the flexibility required for internal implantation. To overcome this, we took the help of induction-heating, the same technology that is used in cooking heaters''. The working of such a device is based on the premise that the magnetic field generated by a coil with a high-frequency current induces current flow in a closely placed metal. Owing to its internal resistance, the metal then heats up automatically.

Developing such an induction heating device required ingenious design. First, the researchers printed the electronic wiring on a polyimide film with an 'ink' made of gold-nanoparticles. Next, a layer of poly (D, L-lactic acid) or PDLLA was coated above the printed film. In addition to heat-durability, the PDLLA layer is biodegradable and biocompatible, making it an excellent candidate for the base material of the device. Then, using tweezers, the researchers peeled off the PDLLA layer, causing it to come off the polyimide film. The result was a flexible device, conformably attaching to human skin, with electronic wirings printed on it.

Once the device showed satisfactory electrical performance, mechanical strength, and heat generation capacity, the researchers assessed its clinical functionality by planting it on living tissue--the hepatic lobe of a beagle dog. The results were extremely promising. When a transmitter coil was placed directly on the device for one minute, the temperature of the liver tissue increased up to 7C without any indication of tissue burning.

Assoc. Prof. Fujie highlights the feat of their research ''The flexibility, biocompatibility, and wireless-powered heating capacity of our device opens up the possibility of using thermotherapy in wide clinical scenarios including minimally invasive endoscopic surgery. Moreover, by adjusting the number and size of these devices, lesions of different sizes can be treated''.

What an incredible localized solution to revolutionize the medical field globally!

####

For more information, please click here

Contacts:
Kazuhide Hasegawa

81-357-342-975

Copyright © Tokyo Institute of Technology

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

RELATED JOURNAL ARTICL

Related News Press

News and information

Getting to the root of tooth replantation challenges: Researchers from Tokyo Medical and Dental University (TMDU) report a delivery system that promotes healing in tooth replantation in rats September 17th, 2021

Researchers reveal multi-path mechanism in electrochemical CO2 reduction September 17th, 2021

Scientists demonstrate pathway to forerunner of nanotubes that could lead to widespread industrial fabrication September 17th, 2021

Silver nanoparticles boost performance of microbial fuel cells September 17th, 2021

Cancer

NYUAD study maps nanobody structure, leading to new ways to potentially fight diseases July 4th, 2021

Researchers turned transparent calcite into artificial gold June 11th, 2021

Targeting Cancer Detection & Identification of Microorganisms, CEA-Leti Develops Mid-Infrared, Spectral-Imaging Technique: Presentations at Photonics West 2021 Show How Early-Stage Imaging Systems Flexibility Can Be Applied Broadly in Medical Field March 18th, 2021

Nanothermometry to improve anticancer strategies February 10th, 2021

Possible Futures

New nano particles suppress resistance to cancer immunotherapy September 17th, 2021

New physics research reveals fresh complexities about electron behavior in materials September 17th, 2021

Scientists demonstrate pathway to forerunner of nanotubes that could lead to widespread industrial fabrication September 17th, 2021

Silver nanoparticles boost performance of microbial fuel cells September 17th, 2021

Nanomedicine

New nano particles suppress resistance to cancer immunotherapy September 17th, 2021

Getting to the root of tooth replantation challenges: Researchers from Tokyo Medical and Dental University (TMDU) report a delivery system that promotes healing in tooth replantation in rats September 17th, 2021

Engineering various sources of loss provides new features for perfect light absorption: "Loss is ubiquitous in nature, and by better understanding it, we make it more useful" September 10th, 2021

Leibniz Prize winner Professor Dr. Oliver G. Schmidt moves to Chemnitz University of Technology: President Professor Dr. Gerd Strohmeier refers to an 'absolute top transfer' September 10th, 2021

Discoveries

Ultrasound at the nanometre scale reveals the nature of force September 17th, 2021

A simple way to get complex semiconductors to assemble themselves: Much like crystallizing rock candy from sugar syrup, the new method grows 2D perovskites precisely layered with other 2D materials to produce crystals with a wide range of electronic properties September 17th, 2021

Getting to the root of tooth replantation challenges: Researchers from Tokyo Medical and Dental University (TMDU) report a delivery system that promotes healing in tooth replantation in rats September 17th, 2021

Researchers reveal multi-path mechanism in electrochemical CO2 reduction September 17th, 2021

Announcements

Getting to the root of tooth replantation challenges: Researchers from Tokyo Medical and Dental University (TMDU) report a delivery system that promotes healing in tooth replantation in rats September 17th, 2021

Researchers reveal multi-path mechanism in electrochemical CO2 reduction September 17th, 2021

Scientists demonstrate pathway to forerunner of nanotubes that could lead to widespread industrial fabrication September 17th, 2021

Silver nanoparticles boost performance of microbial fuel cells September 17th, 2021

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters

New nano particles suppress resistance to cancer immunotherapy September 17th, 2021

New physics research reveals fresh complexities about electron behavior in materials September 17th, 2021

Good for groundwater bad for crops? Plastic particles release pollutants in upper soil layers: The environmental geoscientists at the Centre for Microbiology and Environmental Systems Science (CMESS) focused on a variety of parameters that contribute to plastic pollution in far September 17th, 2021

Ultrasound at the nanometre scale reveals the nature of force September 17th, 2021

Nanobiotechnology

New nano particles suppress resistance to cancer immunotherapy September 17th, 2021

Getting to the root of tooth replantation challenges: Researchers from Tokyo Medical and Dental University (TMDU) report a delivery system that promotes healing in tooth replantation in rats September 17th, 2021

Leibniz Prize winner Professor Dr. Oliver G. Schmidt moves to Chemnitz University of Technology: President Professor Dr. Gerd Strohmeier refers to an 'absolute top transfer' September 10th, 2021

Imaging single spine structural plasticity at the nanoscale level: Researchers at the Max Planck Florida Institute for Neuroscience (MPFI) have developed a new imaging technique capable of visualizing the dynamically changing structure of dendritic spines with unprecedented resol September 3rd, 2021

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project