Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > UTEP researchers help bring biofriendly materials to drug design for neuro disorders

The contributions of researchers from The University of Texas at El Paso have yielded the first indication that carbon quantum dots, a class of nanoparticles, can be utilized to combat neurological disorders.

CREDIT
Mahesh Narayan
The contributions of researchers from The University of Texas at El Paso have yielded the first indication that carbon quantum dots, a class of nanoparticles, can be utilized to combat neurological disorders. CREDIT Mahesh Narayan

Abstract:
The contributions of researchers from The University of Texas at El Paso (UTEP) have yielded the first indication that carbon quantum dots, a class of nanoparticles, can be utilized to combat neurological disorders, according to a paper published in the journal Processes as part its special issue on protein biosynthesis and drug design and delivery.

UTEP researchers help bring biofriendly materials to drug design for neuro disorders

El Paso, TX | Posted on June 5th, 2020

The study, titled "Untangling the Potential of Carbon Quantum Dots in Neurodegenerative Disease," was co-authored by Sreeprasad T. Sreenivasan, Ph.D., and Mahesh Narayan, Ph.D., assistant professor and professor, respectively, in UTEP's Department of Chemistry and Biochemistry. The pair contributed to work by Prakash Narayan, Ph.D., vice president of preclinical research for Angion Biomedica Corp. in Uniondale, New York; and Lindsey Jung, a student at Tenafly High School in New Jersey, who works under Prakash Narayan's supervision.

The study focuses on carbon quantum dots (CQDs), biofriendly materials synthesized from waste materials such as wood, fruit peel, algae and even salmon. A road map laid out by the research team addresses, for the first time, key requirements for the transitioning of their use from environmental-sensing applications into the neurodegenerative domain; a crossing-over that requires their separation and total characterization, including aspects related to safety and their ability to target specific receptors in the brain.

"The carbonaceous quanta are finally making their way from physics into chemistry and now, biology," Prakash Narayan said. "This work lays the foundation for harnessing the enormous potential of carbon quantum dots for therapeutic intervention in neuro disease."

The CQDs are made by "pressure-cooking" waste biomaterials such as fruit peel, amino acids, algae and even fish. As an outcome of the procedure, they are synthesized as a mixture of carbon dots and non-carbon dots. Some of the compounds in the mixture can be toxic. This aspect would negate their use in biomedical applications.

To facilitate the crossing-over of CQDs into preclinical and eventually clinical use, the research team provides a path for their safe use while demonstrating their potential to both prevent and treat neurodegenerative disorders, Mahesh Narayan said.

The research was conducted at Angion Biomedica, and at UTEP's Functional Quantum Materials Laboratory and the Laboratory for Neurodegenerative Research.

The transitioning of CQD applications from electrochemistry, catalysis and environmental sensing to biomedicine represents an important milestone in its 15-year history; a bellwether for its yet-unrealized potential in interventional biology, imaging, diagnostics, prophylaxis and therapy.

"This will allow pharmaceutical companies to tailor carbon quantum dots for specific uses," Mahesh Narayan said. "Individuals with Parkinson's and Alzheimer's could benefit greatly from this kind of therapy."

####

For more information, please click here

Contacts:
Victor H. Arreola

915-747-6437

@UTEP_Research

Copyright © University of Texas at El Paso

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

To read the full paper, visit:

Related News Press

News and information

Phytoplankton disturbed by nanoparticles: Due to its antibacterial properties, nanosilver is used in a wide range of products from textiles to cosmetics; but nanosilver if present at high concentrations also disrupts the metabolism of algae that are essential for the aquatic food November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

One-way street for electrons: Scientists observe directed energy transport between neighbouring molecules in a nanomaterial November 27th, 2020

New insights into memristive devices by combining incipient ferroelectrics and graphene November 27th, 2020

Possible Futures

Russian scientists improve 3D printing technology for aerospace composites using oil waste November 27th, 2020

Phytoplankton disturbed by nanoparticles: Due to its antibacterial properties, nanosilver is used in a wide range of products from textiles to cosmetics; but nanosilver if present at high concentrations also disrupts the metabolism of algae that are essential for the aquatic food November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

One-way street for electrons: Scientists observe directed energy transport between neighbouring molecules in a nanomaterial November 27th, 2020

Nanomedicine

An ionic forcefield for nanoparticles: Tunable coating allows hitch-hiking nanoparticles to slip past the immune system to their target November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

Arrowhead Pharmaceuticals Announces Closing of Agreement with Takeda November 27th, 2020

Arrowhead Pharmaceuticals Reports Fiscal 2020 Year End Results November 23rd, 2020

Discoveries

An ionic forcefield for nanoparticles: Tunable coating allows hitch-hiking nanoparticles to slip past the immune system to their target November 27th, 2020

Russian scientists improve 3D printing technology for aerospace composites using oil waste November 27th, 2020

Phytoplankton disturbed by nanoparticles: Due to its antibacterial properties, nanosilver is used in a wide range of products from textiles to cosmetics; but nanosilver if present at high concentrations also disrupts the metabolism of algae that are essential for the aquatic food November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

Announcements

Phytoplankton disturbed by nanoparticles: Due to its antibacterial properties, nanosilver is used in a wide range of products from textiles to cosmetics; but nanosilver if present at high concentrations also disrupts the metabolism of algae that are essential for the aquatic food November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

One-way street for electrons: Scientists observe directed energy transport between neighbouring molecules in a nanomaterial November 27th, 2020

New insights into memristive devices by combining incipient ferroelectrics and graphene November 27th, 2020

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters

Russian scientists improve 3D printing technology for aerospace composites using oil waste November 27th, 2020

Phytoplankton disturbed by nanoparticles: Due to its antibacterial properties, nanosilver is used in a wide range of products from textiles to cosmetics; but nanosilver if present at high concentrations also disrupts the metabolism of algae that are essential for the aquatic food November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

One-way street for electrons: Scientists observe directed energy transport between neighbouring molecules in a nanomaterial November 27th, 2020

Quantum Dots/Rods

Improving quantum dot interactions, one layer at a time: Scientists have found a way to control an interaction between quantum dots that could lead to more efficient solar cells November 20th, 2020

Breakthrough quantum-dot transistors create a flexible alternative to conventional electronics: Quantum dot logic circuits provide the long-sought building blocks for innovative devices, including printable electronics, flexible displays, and medical diagnostics October 30th, 2020

A quantum material-based diagnostic paint to sense problems before structural failure October 23rd, 2020

Turning a hot spot into a cold spot: Fano-shaped local-field responses probed by a quantum dot October 9th, 2020

Nanobiotechnology

An ionic forcefield for nanoparticles: Tunable coating allows hitch-hiking nanoparticles to slip past the immune system to their target November 27th, 2020

Quantum nanodiamonds may help detect disease earlier: The quantum sensing abilities of nanodiamonds can be used to improve the sensitivity of paper-based diagnostic tests, potentially allowing for earlier detection of diseases such as HIV, according to a study led by UCL research November 27th, 2020

Arrowhead Pharmaceuticals Announces Closing of Agreement with Takeda November 27th, 2020

Arrowhead Pharmaceuticals Reports Fiscal 2020 Year End Results November 23rd, 2020

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project