Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > 2D sandwich sees molecules with clarity: Rice University engineers adapt 2D ‘sandwich’ for surface-enhanced Raman spectroscopy

Monolayer Janus MoSSe, a compound of molybdenum, sulfur and selenium developed at Rice University, is adept at detecting biomolecules via surface-enhanced Raman spectroscopy. Its nonmetallic nature helps by curtailing background noise in the signal. (Credit: Lou Group/Rice University)
Monolayer Janus MoSSe, a compound of molybdenum, sulfur and selenium developed at Rice University, is adept at detecting biomolecules via surface-enhanced Raman spectroscopy. Its nonmetallic nature helps by curtailing background noise in the signal. (Credit: Lou Group/Rice University)

Abstract:
A sandwich of molybdenum, sulfur and selenium turns out to be deliciously useful for detecting biomolecules.

2D sandwich sees molecules with clarity: Rice University engineers adapt 2D ‘sandwich’ for surface-enhanced Raman spectroscopy

Houston, TX | Posted on May 15th, 2020

platform for improving the detection of biomolecules via surface-enhanced Raman spectroscopy (SERS).

Using glucose to test the material proved its ability to boost its Raman enhancement factor by more than 100,000 times, which the researchers say is comparable to the highest-reported enhancement factor for 2D substrates.

SERS is an established technique that enables the detection and identification of small concentrations of molecules — or even single molecules — that get close to or adsorbed by metallic surfaces, including nanoparticles. It’s often used to detect nanoscale proteins in bodily fluids, helping to detect diseases and determine treatments, and in environmental analysis.

But metallic SERS media often prompt side reactions that create background noise. Janus MoSSe synthesized at Rice is nonmetallic. “This work mainly addresses whether we can enhance the target molecules' signal strength,” said materials scientist and principal investigator Jun Lou. “We wanted to know if we could make it stand out from the background noise.”

The answer was clearly yes, as Lou and his team reported in Nanoscale.

MoSSe introduced by the Lou lab in 2017 was produced by chemical vapor deposition. Molybdenum sits in the middle with a layer of sulfur on one side and another of selenium on the other; hence the two-faced Janus characterization.

The different electronegativities of each layer make it a SERS superstar, said lead author and Rice alumnus Shuai Jia, a former graduate student in Lou’s lab.

“The dipole created between the top sulfur and the bottom selenium lands out-of-plane, and this creates an electrical field a few nanometers beyond the MoSSe,” Jia said. That field interacts with molecules that come close, enhancing their vibrational intensity enough to be detected.

The researchers noted tests with MoSSe also detected molecules of the neurotransmitter dopamine and that the substrate should be adaptable to sense other molecules.

Lou said there’s room for improvement. “We’re looking at hybrids of MoSSe with some metallic nanoparticles, and also trying to enhance the dipole strength,” he said.

Co-authors of the paper are postdoctoral researchers Jing Zhang and Weipeng Wang and graduate student Tianshu Zhai of Rice, and postdoctoral researchers Arkamita Bandyopadhyay and Hemant Kumar and Vivek Shenoy, the Eduardo D. Glandt President's Distinguished Professor of materials science and engineering, mechanical engineering and applied mechanics and of bioengineering, at the University of Pennsylvania. Lou is a professor of materials science and nanoengineering and of chemistry.

The Welch Foundation and the National Science Foundation supported the research.

####

About Rice University
Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,962 undergraduates and 3,027 graduate students, Rice’s undergraduate student-to-faculty ratio is just under 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for lots of race/class interaction and No. 4 for quality of life by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance.

Follow Rice News and Media Relations via Twitter @RiceUNews.

For more information, please click here

Contacts:
Jeff Falk
713-348-6775


Mike Williams
713-348-6728

Copyright © Rice University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Read the abstract at:

2-faced 2D material is a first at Rice:

Lou Group:

Department of Materials Science and NanoEngineering:

George R. Brown School of Engineering:

Related News Press

News and information

Controlling chemical catalysts with sculpted light January 15th, 2021

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Quantum computers to study the functioning of the molecules of life: A team of theoretical physicists from the University of Trento has shown that it is possible to use quantum computers to simulate processes of great biological importance, such as changes in the shape of protein January 15th, 2021

Keeping the costs of superconducting magnets down using ultrasound: Scientists show ultrasonication is a cost-effective approach to enhance the properties of magnesium diboride superconductors January 15th, 2021

2 Dimensional Materials

New way to control electrical charge in 2D materials: Put a flake on it January 15th, 2021

Ultra-fast gas flows through tiniest holes in 2D membranes: Researchers from the National Graphene Institute at the University of Manchester and the University of Pennsylvania identify ultra-fast gas flows through atomic-scale apertures in 2D membrane and validate a century-old e December 18th, 2020

Faraday fabrics? MXene-coated fabric could contain electronic interference in wearable devices December 11th, 2020

Staying ahead of the curve with 3D curved graphene November 20th, 2020

Govt.-Legislation/Regulation/Funding/Policy

Controlling chemical catalysts with sculpted light January 15th, 2021

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Researchers realize efficient generation of high-dimensional quantum teleportation January 14th, 2021

Chemists invent shape-shifting nanomaterial with biomedical potential It converts from sheets to tubes and back in a controllable fashion January 13th, 2021

Possible Futures

Scientists' discovery is paving the way for novel ultrafast quantum computers January 15th, 2021

Physicists propose a new theory to explain one dimensional quantum liquids formation January 15th, 2021

Controlling chemical catalysts with sculpted light January 15th, 2021

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Nanomedicine

Chemists invent shape-shifting nanomaterial with biomedical potential It converts from sheets to tubes and back in a controllable fashion January 13th, 2021

Single-dose COVID-19 vaccine triggers antibody response in mice January 8th, 2021

Nanocrystals that eradicate bacteria biofilm January 8th, 2021

Detecting COVID-19 antibodies in 10-12 seconds January 8th, 2021

Discoveries

Physicists propose a new theory to explain one dimensional quantum liquids formation January 15th, 2021

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Quantum computers to study the functioning of the molecules of life: A team of theoretical physicists from the University of Trento has shown that it is possible to use quantum computers to simulate processes of great biological importance, such as changes in the shape of protein January 15th, 2021

Keeping the costs of superconducting magnets down using ultrasound: Scientists show ultrasonication is a cost-effective approach to enhance the properties of magnesium diboride superconductors January 15th, 2021

Announcements

Controlling chemical catalysts with sculpted light January 15th, 2021

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Quantum computers to study the functioning of the molecules of life: A team of theoretical physicists from the University of Trento has shown that it is possible to use quantum computers to simulate processes of great biological importance, such as changes in the shape of protein January 15th, 2021

Keeping the costs of superconducting magnets down using ultrasound: Scientists show ultrasonication is a cost-effective approach to enhance the properties of magnesium diboride superconductors January 15th, 2021

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters

Controlling chemical catalysts with sculpted light January 15th, 2021

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Quantum computers to study the functioning of the molecules of life: A team of theoretical physicists from the University of Trento has shown that it is possible to use quantum computers to simulate processes of great biological importance, such as changes in the shape of protein January 15th, 2021

Keeping the costs of superconducting magnets down using ultrasound: Scientists show ultrasonication is a cost-effective approach to enhance the properties of magnesium diboride superconductors January 15th, 2021

Environment

Phytoplankton disturbed by nanoparticles: Due to its antibacterial properties, nanosilver is used in a wide range of products from textiles to cosmetics; but nanosilver if present at high concentrations also disrupts the metabolism of algae that are essential for the aquatic food November 27th, 2020

Flash graphene rocks strategy for plastic waste: Rice University lab detours potential environmental hazard into useful material October 30th, 2020

New design principles for spin-based quantum materials: Criteria for designing targeted quantum materials could support Internet of Things devices and other resource-intensive technologies September 20th, 2020

Nano-diamond self-charging batteries could disrupt energy as we know it August 25th, 2020

Grants/Sponsored Research/Awards/Scholarships/Gifts/Contests/Honors/Records

Conductive nature in crystal structures revealed at magnification of 10 million times: University of Minnesota study opens up possibilities for new transparent materials that conduct electricity January 15th, 2021

Chemists invent shape-shifting nanomaterial with biomedical potential It converts from sheets to tubes and back in a controllable fashion January 13th, 2021

Nanoparticle vaccine for COVID-19 January 8th, 2021

Transition metal 'cocktail' helps make brand new superconductors: Concept of high entropy alloys provides a discovery platform for new superconductors January 8th, 2021

Nanobiotechnology

Chemists invent shape-shifting nanomaterial with biomedical potential It converts from sheets to tubes and back in a controllable fashion January 13th, 2021

Nanoparticle vaccine for COVID-19 January 8th, 2021

Single-dose COVID-19 vaccine triggers antibody response in mice January 8th, 2021

Nanocrystals that eradicate bacteria biofilm January 8th, 2021

Research partnerships

Chemists invent shape-shifting nanomaterial with biomedical potential It converts from sheets to tubes and back in a controllable fashion January 13th, 2021

Nanocrystals that eradicate bacteria biofilm January 8th, 2021

Quantum wave in helium dimer filmed for the first time: Collaboration between Goethe University and the University of Oklahoma December 30th, 2020

Researchers develop new way to break reciprocity law: The breakthrough makes a significant step forward in photonics and microwave technology by eliminating the need for bulky magnets December 29th, 2020

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project