Home > Press > Bacterial outer membrane vesicles: An emerging tool in vaccine development: This article by Kendrick B. Turner and Scott A. Walper is published in Drug Delivery Letters, Volume 7, Issue 2, 2017
Engineered bacterial OMV. CREDIT Kendrick B. Turner and Scott A. Walper, Bentham Science Publishers |
Abstract:
Outer membrane vesicles, biological nanoparticles shed during normal growth by bacteria, have seen significant recent advances in engineering and are thus finding new utility as therapeutic and drug delivery agents.
One specific research focus explored recently in the literature is the use of bacterial vesicles as adjuvants in vaccine formulations. Early success in this area has demonstrated protection against infection by a number of bacterial species in animal models by engineering vesicles to display species-specific antigens as cargo, either within the interior of the vesicles or displayed on the exterior vesicle surface. In an effort to highlight recent advances in this field, this article explores recent and ongoing efforts to develop novel engineering methods aimed at providing new functionalities for bacterial vesicles as they apply to vaccine formulations. Specifically emerging technologies for engineering these structures, including cargo loading and surface modification will be explored. Bacterial vesicles show great promise as biologically-, derived nanoparticles that could function as a platform technology in a variety of fields. With continued development of novel engineering tools, and an increased understanding in their biogenesis and biological fate in living systems there is significant potential to develop bacterial vesicles as tools for not only vaccine development but also for use in the delivery of therapeutic compounds to targeted cells.
####
For more information, please click here
Contacts:
Faizan ul Haq
Copyright © Bentham Science Publishers
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related Links |
Related News Press |
News and information
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Possible Futures
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
With VECSELs towards the quantum internet Fraunhofer: IAF achieves record output power with VECSEL for quantum frequency converters April 5th, 2024
Nanomedicine
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Discoveries
Chemical reactions can scramble quantum information as well as black holes April 5th, 2024
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Utilizing palladium for addressing contact issues of buried oxide thin film transistors April 5th, 2024
Announcements
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Nanobiotechnology
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
The latest news from around the world, FREE | ||
Premium Products | ||
Only the news you want to read!
Learn More |
||
Full-service, expert consulting
Learn More |
||