Home > Press > Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors
Abstract:
Iranian researchers produced a biosensor with high sensitivity and selectivity, in a laboratorial study, which can successfully detect a type of bacterium that causes salmonella poisoning in food samples.
This research focuses on electrochemical biosensors based on DNA stabilization on the surface of modified electrodes. The reason is the important characteristics of these sensors, including high sensitivity, high selectivity, ease of production, repeatability and reasonable price.
One of the electrodes used in the production of these sensors is the electrode modified with carbon nanomaterials. Glass carbon porous nanomaterial is one of the useful carbon nanomaterials used in the production of these electrodes. DNA sequence of salmonella bacterium was stabilized on glass carbon nanoporous electrode, and the final biosensors were used to measure the bacteria in the food sample.
Results showed that the changes in DNA can be measured at very high sensitivity and selectivity by using the produced biosensor. Ease of production, low cost, good accuracy and reliability, appropriate response range, and very low detection limit are among the other important properties of the biosensor. This sensor can be used in clinical medical fields and laboratorial sciences to quickly detect the type of bacteria in patients, and in foodstuff industry to control the quality of food products and to detect contaminated products.
Results of the research have been published in Biosensors and Bioelectronics, vol. 69, issue 1, 2015, pp. 100-105.
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