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Home > Press > Iranian Scientists Eliminate Expensive Materials from Diabetes Diagnosis Sensors

Abstract:
Iranian researchers designed and produced a non-enzyme biosensor at the laboratorial scale to detect diabetes.

Iranian Scientists Eliminate Expensive Materials from Diabetes Diagnosis Sensors

Tehran, Iran | Posted on March 25th, 2015

Reducing the production cost, increasing the rate of glucose detection and increasing the stability are among the achievements of the research. Medical and clinical sciences, biology and food stuff can use the advantages of the sensor.

The aim of the research was not only the production of a non-enzyme biosensor to detect glucose, but also to eliminate the expensive nafion and glucose oxidase enzyme in the design and production of the sensor. Therefore, a sensor has been designed in this research that has good sensitivity, appropriate detection limit, high stability and selectivity against disturbing agents such as dopamine, uric acid, and so on.

Nafion polymer is used in enzyme or non-enzyme sensors to help the stabilization of the desirable compound on the electrode. This material also increases the selectivity of the sensor to the desired electrolyte. However, it is very expensive and it is not easily available. Therefore, efforts have been made in this research to stabilize the desired oxide on the electrode by using cheap multi-walled carbon nanotubes and ethylene glycol. Results showed that the selectivity of the produced sensor to glucose is very good despite the absence of nafion.

The sensor is able to detect glucose very well at blood standardized media in the presence of various disturbing agents. The important point is that the majority of non-enzyme sensors detect glucose at alkaline media. However, the detection of glucose is possible in this research at pH value and chemical environment of blood.

Results of the research have been published in Biosensors and Bioelectronics, vol. 67, issue 1, 2015, pp. 601-607.

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