Home > Press > Novel Method to Determine Optical Purity of Drug Components
Abstract:
Iranian researchers presented a novel method to measure and determine the medical formulations and purity of chiral materials in them.
The proposed method is cheap, sensitive and simple in comparison with the existing methods, and it does not need any separation process.
Many chemical compounds used in the formulation of drugs have one or a few chiral centers. Various enantiomers of the chiral compounds show different biological activities in the living systems during the medical and pharmaceutical processes. The difference can be so great that one of the enantiomers shows the desirable medical properties while another enantiomer is known as a highly toxic component for the biological environment.
Strict standards have been devised to deal with chiral compounds and their purity. Therefore, sensitive and precise detection methods are required to determine the purity. As a result, the main objective of the research was to present a sensitive, applied, quick, reliable and cost-efficient method for the analysis of chiral compounds.
In this research, a novel method was presented based on the resonance of light scattering for the measurement of enantiomers of the target components in the presence of one another. The proposed method enables the determination and measurement of enantiomers at the range of nanogram per liter with high sensitivity and selectivity in the presence of various enantiomers. The obtained results can be used in all industries that deal with the synthesis of organic materials for biological purposes.
Results obtained from laboratorial samples show that the method is practically acceptable and it has high reliability.
Results of the research have been published in Sensors and Actuators B: Chemical, vol. 210, issue 1, 2015, pp. 439-455.
####
For more information, please click here
Copyright © Fars News Agency
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Related News Press |
News and information
Researchers develop artificial building blocks of life March 8th, 2024
Nanomedicine
High-tech 'paint' could spare patients repeated surgeries March 8th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Discoveries
What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024
Researchers’ approach may protect quantum computers from attacks March 8th, 2024
High-tech 'paint' could spare patients repeated surgeries March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Announcements
What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters
Researchers develop artificial building blocks of life March 8th, 2024
Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024
Industrial
Boron nitride nanotube fibers get real: Rice lab creates first heat-tolerant, stable fibers from wet-spinning process June 24th, 2022
Nanotubes: a promising solution for advanced rubber cables with 60% less conductive filler June 1st, 2022
Protective equipment with graphene nanotubes meets the strictest ESD safety standards March 25th, 2022
OCSiAl receives the green light for Luxembourg graphene nanotube facility project to power the next generation of electric vehicles in Europe March 4th, 2022
The latest news from around the world, FREE | ||
Premium Products | ||
Only the news you want to read!
Learn More |
||
Full-service, expert consulting
Learn More |
||