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Home > Press > European Commission opens the gate towards the implementation of Nanomedicine Translation Hub

Abstract:
A major step in implementing the ETPN Translation Hub has been reached, with three European projects entering the finalisation stage of their EU Grant Agreements. The project ENATRANS is for networking of SMEs in the nano-biomedical sector and supporting the SMEs with getting their products from the laboratory phase to the clinical applications. The projects 'NANOFACTURING' and 'NANOPILOT' will establish pilot lines to scale-up the production of novel nanopharmaceuticals from the lab-scale to the quantities needed for clinical testing. This announcement took place during the ETPN Annual Event 2014 in San Sebastian, Spain.

European Commission opens the gate towards the implementation of Nanomedicine Translation Hub

Berlin, Germany | Posted on October 16th, 2014

The ENATRANS project (Enabling NAnomedicine TRANSlation) will ensure the global coherence of the Translation Hub and build a functioning supply chain of nanomedicine projects mainly ran by SMEs and ready to meet industrial and clinical needs. A Translational Advisory Board (TAB) will serve as the cornerstone to provide specific advice, guidance and recommendations to all nanomedicine actors dealing with translation issues and in need of assistance in specific areas of expertise.

Coordinator: ETPN Secretariat c/o VDI/VDE-IT (DE)
Consortium: Nanobiotix (FR), CEA-Leti (FR), Bioanalytik Muenster e.V. (DE), Tel-Aviv University (IL), Fondazione Don Carlo Gnocchi ONLUS (IT), and TecMinho (PT).
Duration: 3 years - Budget: € 2 Mio.

The NanoFacturing project has two principal objectives. Firstly to scale up an existing Good Manufacturing Practice (GMP) pilot line to a medium scale sustainable manufacturing process for solid core nanopharmaceuticals with a primary focus on glycan-coated gold nanoparticles. The process will also support consortium partners' clinical programs such as IFOM's antiviral Dengue fever NP and other EU-wide nanomedicine programs. Secondly to create a large scale process platform that would serve as the basis for GMP compliant industrial manufacture and that will be available as a model for other European companies wishing to develop their own products.

Coordinator: Midatech Biogune (ES)
Consortium: Centre for Process Innovation Limited (UK), Prochimia Surfaces SP.Z.O.O (PL), Galchimia S.A (ES), the University College Dublin and the National University of Ireland (IE), Applus S.A. LGAI Technological Center, S.A (ES), IFOM, Fondazione Istituto FIRC di Oncologia Molecolare (IT), and Ecole Polytechnique Federale de Lausanne (CH).
Duration: 4 years - Budget: € 8 Mio.

The NanoPilot project will build a pilot line for the production of polymer based nanopharmaceuticals in compliance with GMP. The size of the plant aims to be very small, with three systems to be produced at the end of the project. Continuous flow microreactors will be employed for two of the nanopharmaceuticals to be manufactured.

Coordinator: the Research Centre IK4-CIDETEC (ES)
Consortium : A Research Institute - UT2A-ADERA (FR); two Universities - National University of Ireland, Galway (IE) and Universidad de Santiago de Compostela (ES) ; two industries - Sylentis (ES) and Chemtrix (NL) ; and three SMEs - iX-Factory (DE), Mejoran (ES) and Spinverse (FI).
Duration: 4 years - Budget: € 6, 28 Mio.

Patrick Boisseau, chairman of the ETPN, added:
"We are very proud to announce such important news during the ETPN Annual Event 2014. The success of the EU calls - 18 proposals have been received for pilot lines for upscaling the manufacturing of nanopharmaceuticals - shows the adequacy of ETPN recommendations with real SMEs needs. We also look forward for the perspectives on a nano-characterisation infrastructure, another major pillar of the Translation Hub asked by European nanomedicine actors. The ETPN is excited to work hand in hand with the different coordinators for a global coherence of actions and a more efficient European value chain in nanomedicine."

The ETPN Annual Event 2014 is taking place in San Sebastian (Spain) from October 15th to 16th, kindly co-organised by the nanoBasque Agency (SPRI) and hosted by CIC nanoGUNE, the Basque nanoscience cooperative research centre.

####

About VDI/VDE-Innovation + Technik GmbH
For High Tech to become a success story, VDI/VDE Innovation + Technik GmbH (VDI/VDE-IT) has been working hard for more than 25 years to be a reliable partner of industry and research and of the political community. With our fields of activity - Research Funding, Technology Politics and Innovation Management – we are covering the entire spectrum of the innovation process, from research through application all the way to the introduction and use of new technologies.

Our customers at home and abroad wish to implement innovations in the high-tech sector. Bringing our knowledge and experience to bear in important key technologies such as microsystems engineering, bio and nano technology and the multimedia, we assist our clients in translating their ideas into action, helping them to make their high-tech projects a success. With this objective in mind, our multidisciplinary team of over 100 experts in the natural and social sciences, engineers, and economists are continuously developing new ideas and methods, tailor-made to the personal needs of our customers.

VDI/VDE Innovation + Technik GmbH is a society of VDI GmbH and of VDE (Association for Electrical, Electronic & Information Technologies).

About ETPN ‐ www.etp‐nanomedicine.eu

The European Technology Platform Nanomedicine was established in 2005 as a joint initiative of the European Commission and CEOs of large industrial companies, SMEs and academic research institutions to investigate and advance joint activities in the area of nanotechnology in medicine. Since 2005 the ETPN published a number of strategic documents, roadmaps and structural requirements for an efficient translation of R&D results into innovative nanomedicine. The ETPN supports its members in coordinating their joint research efforts and improving communication amongst the members as well as towards the European Commission and the European Member States.

About Midatech - http://midatechgroup.com/

Midatech is a world leader in the design, synthesis and manufacture of biocompatible gold nanoparticles (GNPs) with a core focus on therapeutics for diabetes and cancer. The Company is also exploring the use of GNPs in other healthcare applications including vaccines, diagnostics and medical imaging.

About IK4 CIDETEC - www.cidetec.es

IK4-CIDETEC is a Research Institute of 125 professionals member of the Research Alliance IK4 in the Basque Country, a private and independent alliance of R&D centres. IK4 CIDETEC is specialised in generating and transferring knowledge and technology in the areas of materials, surfaces and energy. NanoPilot will be coordinated by the CIDETEC Biomaterials Unit specialised in the synthesis and characterisation of biomaterials (polymer nanoparticles, colloids, hydrogels and bioactive surfaces).

DISCLAIMER:

The above mentioned CSA and GMP Pilot Lines proposals have been positively evaluated by the European Commission‘s services and are under finalisation. Changes in the projects’ duration, consortium, budget or activities may thus occur within the next months.

For more information, please click here

Contacts:
Wiebke Ehret
+49 30 310078-125


ETPN Secretariat - ENATRANS Coordinator
Nicolas Gouze
Head of Secretariat


Midatech – NanoFacturing Coordinator
Justin Barry
CEO Midatech Biogune S.L.


IK4 CIDETEC – NanoPilot Coordinator
Dr. Iraida Loinaz
Head of Biomaterials Unit

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